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About 215 results

ALLMedicine™ Ichthyosiform Erythroderma Center

Research & Reviews  77 results

An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With Ichthyoses
https://clinicaltrials.gov/ct2/show/NCT04549792

Apr 20th, 2022 - The ichthyoses are a group of lifelong genetic disorders that share characteristics of generalized skin thickening, scaling and underlying cutaneous inflammation. The vast majority are orphan disorders and are associated with extremely poor qualit...

Genotype of autosomal recessive congenital ichthyosis from a tertiary care center in In...
https://doi.org/10.1111/pde.14944
Pediatric Dermatology; Chiramel MJ, Mathew L et. al.

Apr 13th, 2022 - Autosomal recessive congenital ichthyosis (ARCI) refers to non-syndromic ichthyosis caused by mutations in one of the 13 identified genes. There are limited data on the genotype of ARCI and its phenotypic correlation from India. The aim of this st...

Lamellar Ichthyosis
https://emedicine.medscape.com/article/1111300-print

Apr 1st, 2022 - Practice Essentials Lamellar ichthyosis (LI) is an autosomal recessive disorder that is apparent at birth and is present throughout life. The newborn is born encased in a collodion membrane that sheds within 10-14 days. The shedding of the membran...

Secukinumab responses vary across the spectrum of congenital ichthyosis in adults.
https://doi.org/10.1007/s00403-022-02325-3 10.1016/j.jaci.2018.03.021 10.1016/j.jid.2018.03.1523 10.1016/j.jaad.2015.05.013 10.1016/j.jid.2017.04.037 10.1111/j.1365-2133.2011.10510 10.1111/pde.14221 10.1111/j.1365-2133.2009.09586 10.1111/j.1365-2133.2008.08832 10.1016/j.jaad.2013.01.022 10.1016/j.jaci.2019.04.029 10.1016/j.jdcr.2020.04.025
Archives of Dermatological Research; Lefferdink R, Rangel SM et. al.

Feb 27th, 2022 - Treatment of congenital ichthyoses primarily focuses on reversing skin scaling and is not pathogenesis based. Recent studies showed Th17 immune skewing, as in psoriasis, across the spectrum of ichthyosis, suggesting that targeting this pathway mig...

A novel pathogenic variant in the corneodesmosin gene causing generalized inflammatory ...
https://doi.org/10.1111/pde.14939
Pediatric Dermatology; Gordon H, Yap P et. al.

Feb 19th, 2022 - Generalized inflammatory peeling skin syndrome (PSS) is a rare autosomal recessive genodermatosis caused by loss-of-function disease-causing variants of the corneodesmosin gene (CDSN), resulting in excessive shedding of the superficial layers of t...

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Clinicaltrials.gov  1 results

An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With Ichthyoses
https://clinicaltrials.gov/ct2/show/NCT04549792

Apr 20th, 2022 - The ichthyoses are a group of lifelong genetic disorders that share characteristics of generalized skin thickening, scaling and underlying cutaneous inflammation. The vast majority are orphan disorders and are associated with extremely poor qualit...

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News  8 results

Despite New Ichthyosis Treatment Recommendations, 'Many Questions Still Exist'
https://www.medscape.com/viewarticle/949188

Apr 13th, 2021 - For as many disorders of cornification and types of ichthyosis that have been shown to benefit from retinoids, a seemingly equal number have no data or show no improvement. According to a consensus statement published in the February issue of Pedi...

Despite new ichthyosis treatment recommendations, ‘many questions still exist’
https://www.mdedge.com/dermatology/article/238473/pediatrics/despite-new-ichthyosis-treatment-recommendations-many
Doug Brunk

Apr 12th, 2021 - For as many disorders of cornification and types of ichthyosis that have been shown to benefit from retinoids, a seemingly equal number have no data or show no improvement. Dr.

Consensus Statement Issued on Retinoids for Ichthyosis, Disorders of Cornification
https://www.medscape.com/viewarticle/945212

Feb 3rd, 2021 - Clinicians using systemic retinoids for treating ichthyosis and other disorders of cornification (DOC) in children and adolescents should aim for the lowest dose possible to balance therapeutic goals with acceptable toxicity levels, advised the au...

Consensus statement issued on retinoids for ichthyosis, disorders of cornification
https://www.mdedge.com/dermatology/article/235419/pediatrics/consensus-statement-issued-retinoids-ichthyosis-disorders
Jennifer Lubell

Feb 2nd, 2021 - Clinicians using systemic retinoids for treating ichthyosis and other disorders of cornification (DOC) in children and adolescents should aim for the lowest dose possible to balance therapeutic goals with acceptable toxicity levels, advised the au.

Tune in to hearing problems in ichthyosis
https://www.mdedge.com/pediatrics/article/76721/pediatrics/tune-hearing-problems-ichthyosis
Patrice Wendling

Jul 30th, 2013 - MILWAUKEE – More than two-thirds of patients with ichthyosis reported hearing problems, based on data from a survey of 135 patients ranging in age from 5 months to 80 years. Overall, 80% of the survey respondents had ear pruritus, 66% had trouble.

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