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About 435 results

ALLMedicine™ Meningocele Center

Research & Reviews  170 results

Natural history of posterior fetal cephaloceles and incidence of progressive cephalocel...
https://doi.org/10.3171/2022.6.PEDS22102
Journal of Neurosurgery. Pediatrics; Gadgil N, McClugage SG et. al.

Jul 29th, 2022 - In utero repair of fetal posterior cephaloceles (meningocele and encephalocele) is being performed based on the premise that fetal surgery prevents progressive herniation of neural tissue and brain damage during pregnancy. However, the extent to w...

Comparison of two surgical approaches in the management of cerebrospinal fluid rhinorrh...
https://doi.org/10.1177/01455613221112760
Ear, Nose, & Throat Journal; Xu M, Wang J et. al.

Jul 8th, 2022 - Cerebrospinal fluid (CSF) leakage from the lateral recess of the sphenoid sinus (LRSS) is usually repaired using endoscopic endonasal approaches, which can be challenging. Various surgical techniques have been developed for the disease. To report ...

Induction of a NOTCH3 Lehman syndrome mutation in osteocytes causes osteopenia in male ...
https://doi.org/10.1016/j.bone.2022.116476
Bone Canalis E, Yee SP et. al.

Jun 28th, 2022 - Lateral Meningocele or Lehman Syndrome (LMS) is associated with NOTCH3 mutations causing deletions of the PEST domain and a gain-of-NOTCH3 function. We demonstrated that Notch3em1Ecan mice harboring Notch3 mutations analogous to those found in LMS...

Progressive-Tension Sutures in Reconstruction of Posterior Trunk Defects in Pediatric P...
https://doi.org/10.1097/PRS.0000000000009331
Plastic and Reconstructive Surgery; Crowe CS, Hauptman JS et. al.

Jun 9th, 2022 - Following neurosurgical repair of spinal dysraphism defects, soft-tissue reconstruction is often required to obtain robust coverage of the dura. Layered closure utilizing local muscle and muscle fascia has proven reliable for this purpose, but it ...

Use of antisense oligonucleotides to target Notch3 in skeletal cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089911
PloS One; Canalis E, Carrer M et. al.

May 11th, 2022 - Notch receptors are determinants of cell fate and function, and play an important role in the regulation of bone development and skeletal remodeling. Lateral Meningocele Syndrome (LMS) is a monogenic disorder associated with NOTCH3 pathogenic vari...

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Clinicaltrials.gov  1 results

Fetoscopic Repair of Isolated Fetal Spina Bifida
https://clinicaltrials.gov/ct2/show/NCT03090633

Oct 7th, 2021 - Spina bifida is a congenital anomaly that results from incomplete closure of the neural tube between 22 and 28 embryological days. Its incidence is approximately 2-4 cases per 10,000 births, and it is considered the most common congenital central ...

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News  2 results

First Report of CSF Leak After COVID-19 Nasal Swab Testing
https://www.medscape.com/viewarticle/938382

Oct 1st, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. A rare case of cerebrospinal fluid (CSF) leak occurred after a healthcare worker inadvertently swabbed a previously unidentified encephalocele dur...

A Newborn Male With a Saclike Lesion: Osmosis USMLE Study Question of the Week
https://www.medscape.com/viewarticle/891225_2

Feb 2nd, 2018 - Answer: D. Surgical intervention within the first few days of life This is a classic presentation of spina bifida, an incomplete closure of the neural tube during the first month of embryonic development. Spina bifida occulta is a mild form in whi...

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Patient Education  1 results see all →