ALLMedicine™ Spina Bifida Center

Mar 15th, 2023 - Understanding the molecular mechanisms that lead to birth defects is an important step towards improved primary prevention. Mouse embryos homozygous for the Kumba (Ku) mutant allele of Zic2 develop severe spina bifida with complete lack of dorsola...

Mar 14th, 2023 - Ondansetron is a widely administered medication for nausea and vomiting of pregnancy. Further examination of its teratogenic capacity is necessary. This study examines the association between ondansetron treatment during pregnancy and birth defect...

Mar 10th, 2023 - Suggested management flowchart in presence of a prenatal diagnosis of open spina bifida.

Mar 7th, 2023 - Objective The purpose of this protocol is to evaluate several configurations of a prototype Extension Assist Knee-Ankle-Foot Orthosis (EA-KAFO) in patients with cerebral palsy (CP), muscular dystrophy (MD), spina bifida (SB), or incomplete spinal ...

Mar 3rd, 2023 - The primary aim of this study was to estimate the prevalence of NTDs at ultrasound examination in communities of Addis Ababa and secondarily to provide a description of the dysmorphology of the NTD cases. We enrolled 958 pregnant women from 20 ran...

Nov 20th, 2020 - La présente directive clinique révisée vise à fournir une mise à jour sur les aspects génétiques, la prévention, le dépistage, le diagnostic et la prise en charge des anomalies du tube neural. Les femmes enceintes ou qui pourraient le devenir. Il ...

Nov 20th, 2020 - This revised guideline is intended to provide an update on the genetic aspects, prevention, screening, diagnosis, and management of fetal neural tube defects. Women who are pregnant or may become pregnant. Neural tube defect screening should be of...

Nov 15th, 2019 - In childhood, the most common reason for a neurogenic bladder is related to spinal dysraphism, mostly myelodysplasia. Herein, we present the EAU/ESPU guidelines in respect to the diagnostics, timetable for investigations and conservative managemen...

Aug 17th, 2019 - The incidence of spina bifida (SB) is higher in the developing world as compared to the United States because of folic acid deficiency during pregnancy. Advances in technology have made prenatal repair of myelomeningocele (MM) possible. The object...

Aug 17th, 2019 - The incidence of spina bifida (SB) in the developing world is higher than in the United States because of malnutrition and folic acid deficiency during pregnancy. Advances in technology have made prenatal repair of myelomeningocele (MM) possible. ...

Mar 7th, 2023 - Objective The purpose of this protocol is to evaluate several configurations of a prototype Extension Assist Knee-Ankle-Foot Orthosis (EA-KAFO) in patients with cerebral palsy (CP), muscular dystrophy (MD), spina bifida (SB), or incomplete spinal ...

Feb 22nd, 2023 - Youth with physical disabilities experience restrictions to participation in community-based activities, leading to poor health outcomes. Personalized participation-based treatment approaches, implemented in the individual's natural environment, a...

Feb 9th, 2023 - In this research the effects of progressive resistance exercise training on endurance and functional mobility in children with spina bifida are assessed.

Feb 6th, 2023 - The care and management of pediatric patients with congenital genitourinary anomalies transitioning to adolescents and later adults is undergoing a period of profound transformation. Due to improvements in surgical and nonsurgical interventions, c...

Feb 3rd, 2023 - Introduction Meningomyelocele (MMC), a form of spina bifida, is the most common congenital anomaly of the central nervous system. It occurs in the first four weeks of pregnancy when the neural tube of the embryo fails to close. Neural tube defects...

I’ve been at CDC for 10 years. I work for the National Center on Birth Defects and Developmental Disabilities, leading a project that works to identify the best ways to care for people with spina bifida across the lifespan. I work for the National...

Mar 9th, 2023 - A very rare intraventricular fetus-in-fetu was surgically removed from a 1-year-old girl with motor delay and an enlarged head circumference, a report from China showed. The fetiform mass was a malformed monochorionic diamniotic twin, reported Chu...

Oct 10th, 2022 - A new stem cell treatment appears to be effective at reversing paralysis and other problems caused by spina bifida in newborns, according to a clinical trial underway at UC Davis Health. So far, three babies have received the unique treatment, whi...

Oct 4th, 2022 - Black and Hispanic adults with spina bifida or cerebral palsy are less likely to attend wellness visits than are White adults with the same pediatric-onset disabilities, a new study finds. Black adults also had lower odds of having a bone density ...

Sep 30th, 2022 - Black and Hispanic adults with spina bifida or cerebral palsy are less likely to attend wellness visits than are White adults with the same pediatric-onset disabilities, a new study finds. Black adults also had lower odds of having a bone density.