ALLMedicine™ Ventricular Septal Defects Center

May 3rd, 2022 - Ventricular septal defect is one of the commonest heart defect in children and closure of this defect with devices has seen a rapid progression over a period of time. The availability of new and safer devices has made the transcatheter closure of ...

Apr 23rd, 2022 - The nucleosome remodeling and deacetylase (NuRD) complex is one of the central chromatin remodeling complexes that mediates gene repression. NuRD is essential for numerous developmental events, including heart development. Clinical and genetic stu...

Apr 6th, 2022 - Left ventricular outflow tract obstruction complicates hypertrophic cardiomyopathy and transcatheter mitral valve replacement. Septal reduction therapies including surgical myectomy and alcohol septal ablation are limited by surgical morbidity or ...

Apr 6th, 2022 - Transcatheter ruptured sinus of valsalva aneurysm (RSOVA) closure is an alternative to surgery. When a restrictive ventricular septal defect (rVSD) coexists, there are doubts about support for an occluder and persistent left ventricular (LV) dilat...

Apr 3rd, 2022 - Retrograde device closure of perimembranous ventricular septal defects (pmVSDs) is an interesting procedure with several technical advantages and encouraging follow-up results. Nevertheless, aortic valve injuries may occur and require sufficient a...

Dec 15th, 2021 - This is a multi-center, observational study to evaluate the safety and probable benefit of the AMPLATZER™ PIVSD Occluder for use in transcatheter closure of muscular ventricular septal defects following a myocardial infarction in the post approval...

May 10th, 2021 - The project provides detailed information on the impact of congenital heart disease on neurodevelopmental outcome in adulthood. The study investigates if brain maturation and development, and the neurocognitive outcome is compromised in patients w...

Nov 20th, 2020 - The objective of this registry is to gain more insight on the clinical use of the Occlutech perimembranous VSD occluder.

Jun 28th, 2019 - The objective of this feasibility study is to investigate the safety of the AMPLATZER Muscular VSD Occluder for the treatment of muscular ventricular septal defects, which are hemodynamically significant and are either isolated or in conjunction w...

Jan 17th, 2019 - Transcatheter closure of PVL has emerged as a new treatment strategy that can be offered to patients with isolated PVL or to those with a very high risk of repeat surgery. The transcatheter approach involves deployment of occlude devices or coils ...

Sep 8th, 2021 - (Reuters Health) - Women with high lipid levels during early pregnancy are at increased risk for having offspring with congenital heart disease, a new study suggests. Researchers examined data on blood lipid levels during pregnancy for 230 women w...

Sep 23rd, 2020 - Repairing ventricular septal defects (VSDs) in childhood did not always prevent impairments in functional capacity decades later, researchers from one center reported. Adults over age 40 had differences in exercise capacity on cardiopulmonary exer...

Dec 19th, 2018 - Mothers who took ondansetron (Zofran) in the first trimester of pregnancy were generally not more likely to have children with congenital malformations, although a small increased risk of oral clefts was observed, according to a retrospective coho...

Sep 13th, 2018 - A patient presented soon after having chest pain. The electrocardiogram (ECG) showed an ST-elevation myocardial infarction (STEMI). The day after acute percutaneous coronary intervention (PCI), cardiac enzymes met the definition of myocardial infa...

Apr 16th, 2018 - CHICAGO — In a retrospective analysis of registry data on more than 10 million live births, the risk for childhood cancers was 2.6-fold higher in children born with nonchromosomal abnormalities than in children born without any defects. In additio...