ALLMedicine™ Adenosine Deaminase 2 Deficiency Center

Jul 21st, 2021 - Deficiency of human adenosine deaminase 2 (DADA2) is an auto-inflammatory inborn error of immunity caused by biallelic deleterious mutations in the gene encoding ADA2. The purpose of this article is to raise awareness among ophthalmologists and pe...

Mar 28th, 2021 - Adenosine Deaminase 2 deficiency (ADA2 deficiency) causes swelling of the blood vessels (vasculitis), leading to decreased blood flow affecting the organs and skin. Though the severity and age of onset can vary, most people with ADA2 deficiency be...

Mar 24th, 2021 - Deficiency of adenosine deaminase 2 (DADA2) is a rare autoinflammatory disease caused by mutations in the ADA2 gene. Few Chinese cases have been reported. We describe and compare the clinical features, genotypes, and treatments of Chinese DADA2 pa...

Feb 26th, 2021 - Adenosine deaminase 2 deficiency (OMIM #615688) is an autosomal recessive disorder characterized by a wide clinical spectrum, including small- and medium-sized vessel vasculopathies, but data focusing on the associated neuroimaging features are st...

Feb 2nd, 2021 - Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive inflammatory disease caused by loss-of-function mutations in both alleles of the ADA2 gene. Most patients with DADA2 exhibit systemic vasculopathy consistent with polyarteritis ...