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About 285 results

ALLMedicine™ Alternating Hemiplegia Of Childhood Center

Research & Reviews  109 results

Observe Alternating Hemiplegia of Childhood (OBSERV-AHC) Study
https://clinicaltrials.gov/ct2/show/NCT04020848

Jan 12th, 2023 - Alternating Hemiplegia of Childhood (AHC) is a rare and serious disease that is in need of effective, and hopefully even curative, therapies. Afflicted patients suffer from severe paralyzing crises, often excruciatingly painful muscle spasms, seve...

ATP1A3-related phenotypes in Chinese children: AHC, CAPOS, and RECA.
https://doi.org/10.1007/s00431-022-04744-w
European Journal of Pediatrics; Huang D, Song X et. al.

Dec 10th, 2022 - The aim of this research is to study the phenotype, genotype, treatment strategies, and short-term prognosis of Chinese children with ATP1A3 (Na+/K+-ATPase alpha 3 gene)-related disorders in Southwest China. Patients with pathogenic ATP1A3 variant...

The Phenotypic Continuum of ATP1A3-Related Disorders.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576304
Neurology Vezyroglou A, Akilapa R et. al.

Oct 4th, 2022 - ATP1A3 is associated with a broad spectrum of predominantly neurologic disorders, which continues to expand beyond the initially defined phenotypes of alternating hemiplegia of childhood, rapid-onset dystonia parkinsonism, and cerebellar ataxia, a...

Alternating hemiplegia of childhood: An electroclinical study of sleep and hemiplegia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524638
PloS One; Poole J, Zagaglia S et. al.

Oct 1st, 2022 - Alternating Hemiplegia of Childhood (AHC) is characterised by paroxysmal hemiplegic episodes and seizures. Remission of hemiplegia upon sleep is a clinical diagnostic feature of AHC. We investigated whether: 1) Hemiplegic events are associated wit...

ATP1A3-related early childhood onset developmental and epileptic encephalopathy respond...
https://doi.org/10.1016/j.braindev.2022.08.009
Brain & Development; Moriyama K, Mizuno T et. al.

Sep 17th, 2022 - VariousATP1A3variant-related diseases have been reported, including alternating hemiplegia of childhood; rapid-onset dystonia-parkinsonism; and cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss syndrome. Moreov...

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Clinicaltrials.gov  5 results

Observe Alternating Hemiplegia of Childhood (OBSERV-AHC) Study
https://clinicaltrials.gov/ct2/show/NCT04020848

Jan 12th, 2023 - Alternating Hemiplegia of Childhood (AHC) is a rare and serious disease that is in need of effective, and hopefully even curative, therapies. Afflicted patients suffer from severe paralyzing crises, often excruciatingly painful muscle spasms, seve...

Natural History Study of ATP1A3-related Disease
https://clinicaltrials.gov/ct2/show/NCT03857607

Jun 6th, 2022 - Alternating hemiplegia of childhood (AHC) is a rare very disabling neurodevelopmental syndrome caused by mutations in the gene ATP1A3. AHC is characterized by paroxysmal events including attacks of hemiplegia (weakness), dystonia (painful stiffeni...

HEmiplegia Arrhythmia Retrospective Trial
https://clinicaltrials.gov/ct2/show/NCT04944927

Jun 30th, 2021 - Alternating Hemiplegia of Childhood (AHC) is a rare and severe disease that is in need of effective, and hopefully even curative, therapies. Afflicted patients suffer from severe paralyzing crises, often excruciatingly painful muscle spasms, sever...

Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood
https://clinicaltrials.gov/ct2/show/NCT02408354

Feb 12th, 2020 - The clinical spectrum of Alternating Hemiplegia of Childhood (AHC) is wide and characterized by the association of permanent and paroxysmal (palsy, dystonia, ocular, epileptic, dysautonomic events) neurological events, with onset in childhood. Mos...

Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO)
https://clinicaltrials.gov/ct2/show/NCT00931164

Mar 31st, 2014 - WHO: The investigators are recruiting children and young adults to participate in a research study who: Have been diagnosed with Alternating Hemiplegia of Childhood (AHC) Are between the ages of 6 months - 25 years old Have at least three 10-minut...

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