ALLMedicine™ Amyloid Neuropathy Center
Research & Reviews 36 results
https://clinicaltrials.gov/ct2/show/NCT03588468
Oct 4th, 2022 - Familial amyloid neuropathies (FAP) are hereditary disease due to a mutation of the tranthyretin gene (TTR). These neuropathies are severe and life frightening. Treatment is based on tafamidis and liver transplantation. Clinical trials of RNAI the...
https://doi.org/10.1016/j.jns.2022.120341
Journal of the Neurological Sciences; Thimm A, Carpinteiro A et. al.
Jul 26th, 2022 - Immunoglobulin light chain (AL) amyloidosis is a life-threatening systemic disease due to plasma cell dyscrasias, which is characterized by amyloid deposition in various tissues. Neurological manifestations, in particular peripheral nervous system...
https://clinicaltrials.gov/ct2/show/NCT03190577
Jul 14th, 2022 - Familial amyloid neuropathy due to transthyretin gene mutations (TTR-FAP) is a rare autosomal dominant inherited disease resulting in the abnormal multi-system deposition of amyloid proteins. These deposits produce a multi-organ disease. AP is usu...
https://clinicaltrials.gov/ct2/show/NCT04828928
Jul 6th, 2022 - Transthyretin (TTR) amyloidosis belongs to a group of severe and multi-systemic diseases caused by an extracellular accumulation of fibrillar proteins arranged in beta-pleated sheets. This pathology can be hereditary (mutations in the TTR gene) or...
https://doi.org/10.1016/j.jns.2022.120329
Journal of the Neurological Sciences; Murakami T, Watanabe H et. al.
Jul 2nd, 2022 - We recently reported evidence of transthyretin (TTR) familial amyloid polyneuropathy (TTR FAP) associated with TTR E61K, which is characterized by late-onset sensory dominant polyneuropathy, autonomic disturbances, and cardiomyopathy. In those TTR...
Clinicaltrials.gov 3 results
https://clinicaltrials.gov/ct2/show/NCT03588468
Oct 4th, 2022 - Familial amyloid neuropathies (FAP) are hereditary disease due to a mutation of the tranthyretin gene (TTR). These neuropathies are severe and life frightening. Treatment is based on tafamidis and liver transplantation. Clinical trials of RNAI the...
https://clinicaltrials.gov/ct2/show/NCT03190577
Jul 14th, 2022 - Familial amyloid neuropathy due to transthyretin gene mutations (TTR-FAP) is a rare autosomal dominant inherited disease resulting in the abnormal multi-system deposition of amyloid proteins. These deposits produce a multi-organ disease. AP is usu...
https://clinicaltrials.gov/ct2/show/NCT04828928
Jul 6th, 2022 - Transthyretin (TTR) amyloidosis belongs to a group of severe and multi-systemic diseases caused by an extracellular accumulation of fibrillar proteins arranged in beta-pleated sheets. This pathology can be hereditary (mutations in the TTR gene) or...
Patient Education 1 results
https://my.clevelandclinic.org/health/diseases/15891-anhidrosis-lack-of-sweat
Apr 19th, 2021 - Overview What is anhidrosis? Anhidrosis is a condition in which you can’t sweat (perspire) normally in one or more areas of your body. Sweating helps remove heat from your body so you can cool down. If you can’t sweat, your body overheats, which c...
