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About 14,383 results

ALLMedicine™ Amyotrophic Lateral Sclerosis Center

Research & Reviews  5,460 results

Role of genetics in amyotrophic lateral sclerosis: a large cohort study in Chinese main...
https://doi.org/10.1136/jmedgenet-2021-107965
Journal of Medical Genetics; Chen YP, Yu SH et. al.

Sep 22nd, 2021 - A large number of new causative and risk genes for amyotrophic lateral sclerosis (ALS) have been identified mostly in patients of European ancestry. In contrast, we know relatively little regarding the genetics of ALS in other ethnic populations. ...

Gold Coast diagnostic criteria increase sensitivity in amyotrophic lateral sclerosis.
https://doi.org/10.1016/j.clinph.2021.08.014
Clinical Neurophysiology : Official Journal of the Intern... Pugdahl K, Camdessanché JP et. al.

Sep 22nd, 2021 - This study evaluates diagnostic accuracy of the proposed 'Gold Coast' (GC) diagnostic criteria for amyotrophic lateral sclerosis (ALS). Five European centres retrospectively sampled consecutive patients referred for electromyography on suspicion o...

Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis.
https://doi.org/10.3791/62699
Journal of Visualized Experiments : JoVE; Currey HN, Liachko NF

Sep 21st, 2021 - The neurodegenerative disease amyotrophic lateral sclerosis (ALS) features progressive loss of motor neurons accompanied by muscle weakness and motor impairment that worsens with time. While considerable advances have been made in determining gene...

Investigating RFC1 expansions in sporadic amyotrophic lateral sclerosis.
https://doi.org/10.1016/j.jns.2021.118061
Journal of the Neurological Sciences; Abramzon Y, Dewan R et. al.

Sep 20th, 2021 - A homozygous AAGGG repeat expansion within the RFC1 gene was recently described as a common cause of CANVAS syndrome. We examined 1069 sporadic ALS patients for the presence of this repeat expansion. We did not discover any carriers of the homozyg...

Impaired recognition of disgust in amyotrophic lateral sclerosis is related to basal ga...
https://doi.org/10.1016/j.nicl.2021.102803
NeuroImage. Clinical; Castelnovo V, Canu E et. al.

Sep 20th, 2021 - In the present study we investigated emotion recognition in pure motor amyotrophic lateral sclerosis (ALS) patients and its relationship with the integrity of basal ganglia, hippocampus and amygdala. Twenty ALS patients without either cognitive or...

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Guidelines  3 results

Provisional best practices guidelines for the evaluation of bulbar dysfunction in amyot...
https://doi.org/10.1002/mus.26408
Muscle & Nerve; Pattee GL, Plowman EK et. al.

Jan 9th, 2019 - Universally established comprehensive clinical bulbar scales objectively assessing disease progression in amyotrophic lateral sclerosis (ALS) are currently lacking. The goal of this working group project is to design a best practice set of provisi...

ESPEN guideline clinical nutrition in neurology.
https://doi.org/10.1016/j.clnu.2017.09.003
Clinical Nutrition (Edinburgh, Scotland); Burgos R, Bretón I et. al.

Dec 25th, 2017 - Neurological diseases are frequently associated with swallowing disorders and malnutrition. Moreover, patients with neurological diseases are at increased risk of micronutrient deficiency and dehydration. On the other hand, nutritional factors may...

Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764728
Neurology Miller RG, Jackson CE et. al.

Oct 14th, 2009 - To systematically review evidence bearing on the management of patients with amyotrophic lateral sclerosis (ALS). The authors analyzed studies from 1998 to 2007 to update the 1999 practice parameter. Topics covered in this section include breaking...

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Drugs  17 results see all →

News  272 results

A Quick Tour of the New Lyme Disease Guideline
https://www.medscape.com/viewarticle/951589

Jun 14th, 2021 - This transcript has been edited for clarity. Hello. This is Paul Auwaerter for Medscape Infectious Diseases, speaking from Johns Hopkins University School of Medicine. Spring is in full swing and tick season has certainly returned. I thought I wou...

Scientists Discover New Genetic Form of ALS in 11 Children
https://www.medscape.com/viewarticle/952489

Jun 7th, 2021 - (Reuters Health) - Scientists have identified four specific, dominant variants of the SPTLC1 gene in 11 children from seven different families who appear to have a new and unique form of amyotrophic lateral sclerosis (ALS). The findings suggest th...

Twofold Increased ALS Risk in Manual Laborers
https://www.medscape.com/viewarticle/949580

Apr 20th, 2021 - Blue-collar workers, particularly carpenters and construction workers, have a significantly increased risk for amyotrophic lateral sclerosis (ALS) compared with white-collar workers, new research shows. Investigators found manual laborers had a tw...

Theatrics, Hypnosis, and the Roots of Modern Neurology
https://www.medscape.com/viewarticle/947504

Mar 15th, 2021 - "Symptoms, then, are in reality nothing but a cry from suffering organs" – Jean-Martin Charcot Nearly 130 years after his death, Jean-Martin Charcot's name still resonates with modern neurologists. The famed 19th century French physician made myri...

New Compound Promising for ALS, Other Upper Motor Neuron Diseases
https://www.medscape.com/viewarticle/947056

Mar 11th, 2021 - NEW YORK (Reuters Health) - A new compound, NU-9, improved diseased upper motor neurons (UMN) in mice and shows promise for treating amyotrophic lateral sclerosis (ALS) in humans, though more work is needed before a clinical trial can be started, ...

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Patient Education  1 results see all →