About 418 results

ALLMedicine™ Antisynthetase Syndrome Center

Research & Reviews  148 results

Autoantibodies: Pathogenic or epiphenomenon.
Best Practice & Research. Clinical Rheumatology; Galindo-Feria AS, Wang G et. al.

Jul 10th, 2022 - Idiopathic inflammatory myopathies (IIM) are heterogeneous autoimmune diseases. There are distinct subgroups, including antisynthetase syndrome, dermatomyositis, polymyositis, immune-mediated necrotizing myopathy, and sporadic inclusion body myosi...

A 25-Year-Old Saudi Woman with a 2-Year History of Antisynthetase Syndrome with Interst...
The American Journal of Case Reports; Alshwairikh LA, Babay Z

Jul 8th, 2022 - BACKGROUND Antisynthetase syndrome (ASS) is a rare systemic autoimmune disease. The clinical features of ASS include interstitial lung disease (ILD), myositis, arthritis, Raynaud's phenomenon, mechanic's hands, and unexplained fever. There is a pa...

Interstitial lung disease progression in patients with anti-aminoacyl transfer-RNA-synt...
Immunology Letters; Ramos-Martínez E, Falfán-Valencia R et. al.

Jun 22nd, 2022 - Patients with anti-tRNA autoantibodies are characterized by arthritis, mechanic´s hands, fever, Raynaud´s phenomenon, and interstitial lung disease (ILD), in at least two clinical scenarios: the antisynthetase syndrome (ASSD) and interstitial pneu...

Identification and Prognosis of Patients With Interstitial Pneumonia With Autoimmune Fe...
Journal of Clinical Rheumatology : Practical Reports on R... Jiwrajka N, Loizidis G et. al.

Jun 14th, 2022 - Patients classified as interstitial pneumonia with autoimmune features (IPAF) have interstitial lung disease (ILD) and features of autoimmunity but do not fulfill criteria for connective tissue diseases (CTDs). Our goal was to identify patients cl...

Thigh MRI in antisynthetase syndrome, and comparisons with dermatomyositis and immune-m...
Rheumatology (Oxford, England); Zhang W, Zheng Y et. al.

May 6th, 2022 - To evaluate MRI changes to define muscle-lesion specific patterns in patients with antisynthetase syndrome (ASS), and compare them with those in other common idiopathic inflammatory myopathy (IIM) subtypes. Qualitative and semi-quantitative thigh ...

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Clinicaltrials.gov  3 results

Association Between Cancer and Anti-synthetase Syndrome

Jun 28th, 2021 - Idiopathic inflammatory myopathies area heterogeneous group of disease involving mainly muscles, which paraneoplastic feature has been well characterized, specifically in some subgroups such as dermatomyositis. In contrast, antisynthetase syndrome...

Evaluation of Interstitial Lung Disease Severity in Patients With Antisynthetase Syndrome According to Specific Autoantibodies Profile

Jun 14th, 2021 - Antisynthetase syndrome (ASS) is an overlap connective tissue disease characterized by the presence of myositis-specific autoantibodies directed against tRNA-synthetases. Clinical manifestations are myositis, interstitial lung disease (ILD), Rayna...

Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease

Feb 9th, 2021 - "During the study period, according to randomization into two groups (n=38 patients, respectively), patients will receive either: - Group 1 & 2 : 3 IV pulses of Methylprednisolone (7.5 mg/kg/day followed by tapering doses of oral Prednisone, start...

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News  16 results

Predicting Treatment Response in Inflammatory Muscle Disorders

Feb 16th, 2022 - Rheumatologists looking for clues to whether their patients with certain inflammatory myopathies will improve on immunosuppressive drugs may find them in a new study appearing in Arthritis Care & Research. Presence of dermatomyositis-specific auto...

Darkening and Eruptive Nevi During Treatment With Erlotinib
Stephen Hemperly, DO, Tanya Ermolovich, DO et. al.

Jul 30th, 2019 - To the Editor: Erlotinib is a small-molecule selective tyrosine kinase inhibitor that functions by blocking the intracellular portion of the epidermal growth factor receptor (EGFR)1,2; EGFR normally is expressed in the basal layer of the epidermis.

Dr. Lisa Christopher-Stine: Polymyositis? It’s more likely something else

Feb 20th, 2019 - Overlap Sometimes patients with polymyositis also have other rheumatologic conditions that shouldn’t be overlooked, therefore “overlap is its own category,” she said. “In our experience, the most common overlap is scleroderma,” she noted, adding t.

Dr. Lisa Christopher-Stine: Polymyositis? It’s more likely something else
Sharon Worcester

Feb 20th, 2019 - True polymyositis is rare, so it’s important to carefully consider other likely diagnoses, according to Lisa Christopher-Stine, MD. Dr.

Anti-TIF1-Ab-Positive Dermatomyositis Linked to Higher Cancer Risk

Dec 13th, 2018 - Action Points Anti-TNF1-Ab positive dermatomyositis (DM) is linked to an elevated risk of cancer, especially ovarian cancer. This risk is present approximately 3 years on either side of DM onset. The link between DM and cancer is present for patie...

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