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About 465 results

ALLMedicine™ Antisynthetase Syndrome Center

Research & Reviews  165 results

Assessment of idiopathic inflammatory myopathy using a deep learning method for muscle ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672653
European Radiology; Wang F, Zhou S et. al.

Nov 18th, 2022 - To investigate the utility of an automatic deep learning (DL) method for segmentation of T2 maps in patients with idiopathic inflammatory myopathy (IIM) against healthy controls, and also the association of quantitative T2 values in patients with ...

Mechanic Hands/Hiker Feet in a Patient With Amyopathic Dermatomyositis and Interstitial...
https://doi.org/10.1097/DAD.0000000000002240
The American Journal of Dermatopathology; Regmi A, Saab-Chalhoub MW et. al.

Nov 18th, 2022 - A 30-year-old African American woman with a history of interstitial lung disease presented with bilaterally symmetrical, nonpruritic, scaling and fissuring, hyperpigmented, lichenified plaques on her hands and feet. She reported occasional erythem...

An observational study of clinical recurrence in patients with interstitial lung diseas...
https://doi.org/10.1007/s10067-022-06424-4
Clinical Rheumatology; Chen H, Liu H et. al.

Nov 6th, 2022 - To describe the clinical characteristics and risk factors of clinical recurrence in interstitial lung disease related to antisynthetase syndrome (ARS-ILD). Patients diagnosed as ARS-ILD in Nanjing Drum Tower Hospital between January 2015 and Novem...

Analysis of the clinical features of antisynthetase syndrome: a retrospective cohort st...
https://doi.org/10.1007/s10067-022-06404-8
Clinical Rheumatology; Wang R, Zhao Y et. al.

Oct 30th, 2022 - To summarize the clinical, serological, and radiological characteristics of anti-synthetase syndrome (ASS) patients with different anti-aminoacyl-tRNA synthase antibody. Retrospective analysis was performed based on the clinical data of 88 patient...

High prevalence of necrotising myopathy pattern in muscle biopsies of patients with ant...
https://doi.org/10.55563/clinexprheumatol/zq7x68
Clinical and Experimental Rheumatology; Silva LMB, Borges IBP et. al.

Oct 14th, 2022 - Until now, researchers have not provided a well-defined muscle histological pattern for antisynthetase syndrome (ASSD). Therefore, we aimed to analyse the muscle biopsies of patients with anti-Jo-1 ASSD. This study included 26 patients with anti-J...

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Clinicaltrials.gov  4 results

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.
https://clinicaltrials.gov/ct2/show/NCT05523167

Oct 10th, 2022 - This study's purpose is to measure the treatment response from efgartigimod PH20 SC compared with placebo in participants with Idiopathic Inflammatory Myopathy (IIM). Participants with the IIM subtypes of dermatomyositis (DM), immune-mediated necr...

Association Between Cancer and Anti-synthetase Syndrome
https://clinicaltrials.gov/ct2/show/NCT04941547

Jun 28th, 2021 - Idiopathic inflammatory myopathies area heterogeneous group of disease involving mainly muscles, which paraneoplastic feature has been well characterized, specifically in some subgroups such as dermatomyositis. In contrast, antisynthetase syndrome...

Evaluation of Interstitial Lung Disease Severity in Patients With Antisynthetase Syndrome According to Specific Autoantibodies Profile
https://clinicaltrials.gov/ct2/show/NCT04924465

Jun 14th, 2021 - Antisynthetase syndrome (ASS) is an overlap connective tissue disease characterized by the presence of myositis-specific autoantibodies directed against tRNA-synthetases. Clinical manifestations are myositis, interstitial lung disease (ILD), Rayna...

Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease
https://clinicaltrials.gov/ct2/show/NCT03770663

Feb 9th, 2021 - "During the study period, according to randomization into two groups (n=38 patients, respectively), patients will receive either: - Group 1 & 2 : 3 IV pulses of Methylprednisolone (7.5 mg/kg/day followed by tapering doses of oral Prednisone, start...

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News  17 results

Predicting Treatment Response in Inflammatory Muscle Disorders
https://www.medpagetoday.com/rheumatology/generalrheumatology/97219

Feb 16th, 2022 - Rheumatologists looking for clues to whether their patients with certain inflammatory myopathies will improve on immunosuppressive drugs may find them in a new study appearing in Arthritis Care & Research. Presence of dermatomyositis-specific auto...

Darkening and Eruptive Nevi During Treatment With Erlotinib
https://www.mdedge.com/dermatology/article/205623/melanoma/darkening-and-eruptive-nevi-during-treatment-erlotinib
Stephen Hemperly, DO, Tanya Ermolovich, DO et. al.

Jul 30th, 2019 - To the Editor: Erlotinib is a small-molecule selective tyrosine kinase inhibitor that functions by blocking the intracellular portion of the epidermal growth factor receptor (EGFR)1,2; EGFR normally is expressed in the basal layer of the epidermis.

Dr. Lisa Christopher-Stine: Polymyositis? It’s more likely something else
https://www.mdedge.com/neurology/article/194807/lupus-connective-tissue-diseases/dr-lisa-christopher-stine-polymyositis-its/page/0/1?channel=39313

Feb 20th, 2019 - Overlap Sometimes patients with polymyositis also have other rheumatologic conditions that shouldn’t be overlooked, therefore “overlap is its own category,” she said. “In our experience, the most common overlap is scleroderma,” she noted, adding t.

Dr. Lisa Christopher-Stine: Polymyositis? It’s more likely something else
https://www.mdedge.com/rheumatology/article/194807/lupus-connective-tissue-diseases/dr-lisa-christopher-stine-polymyositis
Sharon Worcester

Feb 20th, 2019 - True polymyositis is rare, so it’s important to carefully consider other likely diagnoses, according to Lisa Christopher-Stine, MD. Dr.

Anti-TIF1-Ab-Positive Dermatomyositis Linked to Higher Cancer Risk
https://www.medpagetoday.com/rheumatology/generalrheumatology/76902

Dec 13th, 2018 - Action Points Anti-TNF1-Ab positive dermatomyositis (DM) is linked to an elevated risk of cancer, especially ovarian cancer. This risk is present approximately 3 years on either side of DM onset. The link between DM and cancer is present for patie...

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