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About 1,848 results

ALLMedicine™ Ependymoma Center

Research & Reviews  687 results

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
https://clinicaltrials.gov/ct2/show/NCT00187226

May 18th, 2022 - Radiation therapy is commonly used to treat a variety of brain tumors in children including ependymoma, craniopharyngioma and low- and high-grade glioma. The ability of the therapy to control brain tumors in children is known to depend on the tumo...

MRI-based texture analysis for differentiate between pediatric posterior fossa ependymo...
https://doi.org/10.1016/j.ejrad.2022.110288
European Journal of Radiology; Cui Z, Ren G et. al.

May 15th, 2022 - The aim of the study was to evaluate the feasibility of texture analysis in differentiating between posterior fossa ependymoma type A (PF-EPN-A) and type B (PF-EPN-B) among children. Our retrospective study included 43 patients (37 PF-EPN-A and 6 ...

Resection of Giant Remote Recurrence of Ependymoma After 41 Years.
https://doi.org/10.1016/j.wneu.2022.04.011
World Neurosurgery; Peto I, Krafft PR et. al.

Apr 13th, 2022 - Ependymomas are rare primary tumors of the brain and spinal cord that arises from the ependymal cell layer. Cranial ependymomas commonly occur in the posterior fossa; however, approximately 30% of all tumors can be found in the supratentorial regi...

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT
https://clinicaltrials.gov/ct2/show/NCT01356290

Apr 8th, 2022 - Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation or combinations of these modalities. Antiangiogenetic ...

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Drugs  10 results see all →

Clinicaltrials.gov  21 results

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
https://clinicaltrials.gov/ct2/show/NCT00187226

May 18th, 2022 - Radiation therapy is commonly used to treat a variety of brain tumors in children including ependymoma, craniopharyngioma and low- and high-grade glioma. The ability of the therapy to control brain tumors in children is known to depend on the tumo...

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT
https://clinicaltrials.gov/ct2/show/NCT01356290

Apr 8th, 2022 - Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation or combinations of these modalities. Antiangiogenetic ...

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer
https://clinicaltrials.gov/ct2/show/NCT05106296

Apr 1st, 2022 - Recent lab-based discoveries suggest that IDO (indoleamine 2,3-dioxygenase) and BTK (Bruton's tyrosine Kinase) form a closely linked metabolic checkpoint in tumor-associated antigen-presenting cells. The central clinical hypothesis for the GCC2020...

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
https://clinicaltrials.gov/ct2/show/NCT04049669

Mar 25th, 2022 - Disease-specific Cohorts : Cohort 1A, 1B: progressive glioblastoma (relapsed or refractory) Cohort 2A, 2B: progressive medulloblastoma (relapsed or refractory) Cohort 3A, 3B, 3C: progressive ependymoma (relapsed or refractory) Cohort 4C: newly-dia...

Study of the Effect of GM-CSF on Macrophages in Ependymoma
https://clinicaltrials.gov/ct2/show/NCT04408092

Feb 9th, 2022 - To study whether Granulocyte Macrophage Colony Stimulation Factor (GM-CSF) increases macrophage infiltration in children with ependymoma (EPN) who are to have planned surgery as a standard procedure for incomplete resection or recurrent tumor. To ...

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News  18 results

Common Diabetes Drug Shrinks Brain Tumors in Mice
https://www.medscape.com/viewarticle/962161

Nov 3rd, 2021 - Many cancers with known genetic causes can be treated by targeting tumors and leaving healthy cells unscathed. But that's not the case for a rare type of brain and spinal cord cancer that primarily strikes children and has no obvious genetic cause...

Persistent Development of WEE1 Pathway Inhibitors Begins to Pay Off
https://www.onclive.com/view/persistent-development-of-wee1-pathway-inhibitors-begins-to-pay-off

Aug 25th, 2021 - WEE1 is a key regulator of the cell cycle that has been a target of cancer drug discovery efforts for more than a decade. The lead novel candidate, the WEE1 inhibitor adavosertib (AZD1775), has been tested in more than 50 completed or ongoing clin...

FDA Grants Rare Pediatric Disease Designation to WP1066 for Ependymoma
https://www.onclive.com/view/fda-grants-rare-pediatric-disease-designation-to-wp1066-for-ependymoma

Apr 14th, 2021 - The FDA has granted a rare pediatric disease (RPD) designation to the p-STAT3 inhibitor WP1066 for the treatment of patients with ependymoma, a rare type of tumor that can develop in the brain or the spinal cord.1 The FDA’s recognition of the h...

Dr. Upadhyaya on Radiation Therapy for Young Children with Ependymoma
https://www.onclive.com/view/dr-upadhyaya-on-radiation-therapy-for-young-children-with-ependymoma

Dec 20th, 2020 - Santhosh Upadhyaya, MD, neuro-oncologist, St. Jude Children’s Research Hospital, discusses radiation therapy for young children under the age of 3 who have ependymoma. He highlighted outcomes of the 10-year-long SJYC07 trial at the 2018 ASCO Annua...

Medulloblastoma Subtypes Are Different Diseases
https://www.onclive.com/view/medulloblastoma-subtypes-are-different-diseases

Dec 5th, 2020 - Medulloblastoma, a malignant brain tumor that most commonly affects children, is not one disease but several, said researchers with St. Jude Children’s Hospital in Memphis, Tennessee. Similar discoveries have been made in other cancers, leading to...

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Patient Education  3 results see all →