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About 3,413 results

ALLMedicine™ Essential Tremor Center

Research & Reviews  1,178 results

Neuropathology of Spasmodic Dysphonia
https://clinicaltrials.gov/ct2/show/NCT00118586

May 13th, 2022 - Spasmodic dysphonia (SD) is a focal dystonia affecting the neural control of the laryngeal musculature for speech production. Although the clinical symptoms of SD have been described, the underlying pathological mechanisms remain unknown. Treatmen...

Sweet spots of standard and directional leads in patients with refractory essential tre...
https://doi.org/10.3171/2022.3.JNS212374
Journal of Neurosurgery; Avecillas-Chasin JM, Honey CR et. al.

May 11th, 2022 - In patients with essential tremor (ET) treated with standard deep brain stimulation (sDBS) whose ET had progressed and who no longer received optimal benefit from sDBS, directional deep brain stimulation (dDBS) may provide better tremor control. C...

DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET)
https://clinicaltrials.gov/ct2/show/NCT05096572

May 11th, 2022 - Essential Tremor (ET) is the most common movement disorder. It is estimated that between 25 and 55% of patients with ET will have a tremor which is refractory to pharmacotherapy necessitating advanced therapeutic options to control tremor. Deep Br...

Epidemiology of Pediatric Essential Tremor in the United States: A Systematic Literatur...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029662
Tremor and Other Hyperkinetic Movements (New York, N.Y.); Gerbasi ME, Eldar-Lissai A et. al.

May 10th, 2022 - Essential tremor (ET) is one of the most common movement disorders worldwide, yet the size of the pediatric ET population is not well understood. The objective of this review was to identify, evaluate, and synthesize evidence describing the epidem...

A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)
https://clinicaltrials.gov/ct2/show/NCT05122650

May 5th, 2022 - This is a 12-week, double-blind, placebo-controlled, randomized, parallel-group, multicenter study of the safety and efficacy of JZP385 in the treatment of adult participants with moderate to severe ET.

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Drugs  38 results see all →

Clinicaltrials.gov  65 results

Neuropathology of Spasmodic Dysphonia
https://clinicaltrials.gov/ct2/show/NCT00118586

May 13th, 2022 - Spasmodic dysphonia (SD) is a focal dystonia affecting the neural control of the laryngeal musculature for speech production. Although the clinical symptoms of SD have been described, the underlying pathological mechanisms remain unknown. Treatmen...

DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET)
https://clinicaltrials.gov/ct2/show/NCT05096572

May 11th, 2022 - Essential Tremor (ET) is the most common movement disorder. It is estimated that between 25 and 55% of patients with ET will have a tremor which is refractory to pharmacotherapy necessitating advanced therapeutic options to control tremor. Deep Br...

A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)
https://clinicaltrials.gov/ct2/show/NCT05122650

May 5th, 2022 - This is a 12-week, double-blind, placebo-controlled, randomized, parallel-group, multicenter study of the safety and efficacy of JZP385 in the treatment of adult participants with moderate to severe ET.

Investigating Inhibitory Control Networks in Parkinson's Disease
https://clinicaltrials.gov/ct2/show/NCT04735458

Apr 22nd, 2022 - Movement disorders are a prominent cause of disability worldwide. In the United States, it is estimated that more than 4 million people suffer from Parkinson's disease (PD), essential tremor (ET), and dystonia, some of the most prevalent of neurol...

[18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor
https://clinicaltrials.gov/ct2/show/NCT04265209

Apr 12th, 2022 - Clinical study to demonstrate an at least equivalent performance of a new PET molecular Imaging radiopharmaceutical named [18F] LBT-999 in brain imaging compared to the SPECT reference method named [123I]-FP-CIT to establish the differential diagn...

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News  79 results

Genetic Variations Explain Essential Tremor Risk
https://www.medscape.com/viewarticle/966553

Jan 13th, 2022 - Several common regions of DNA are linked to an increased risk of developing essential tremor (ET), new research shows. Investigators studied more than 480,000 adults and found five genetic loci that were significantly associated with ET risk, part...

Novel Drug Effective for Essential Tremor, but With Significant Side Effects
https://www.medscape.com/viewarticle/959811

Sep 27th, 2021 - The investigational oral, neuroactive, steroid-positive allosteric modulator SAGE-324/BIIB124 (SAGE-324) is effective for treating essential tremor ― but problems with tolerability may limit its usefulness, new research suggests. The phase 2 KINET...

Low-Intensity Focused Ultrasound Safe, Effective in Mild Alzheimer's Disease
https://www.medscape.com/viewarticle/957487

Aug 30th, 2021 - A new noninvasive procedure is safe and effective for treating patients with mild Alzheimer's disease (AD), new research suggests. Clinicians monitor a trial patient with AD undergoing low-intensity focused ultrasound. The approach uses MRI-guided...

FDA Clears Next-Generation DBS System for Movement Disorders
https://www.medscape.com/viewarticle/952660

Jun 8th, 2021 - The US Food and Drug Administration (FDA) has approved Medtronic's technologically advanced deep brain stimulation (DBS) system designed to more precisely target motor symptoms in Parkinson's disease, dystonia, or essential tremor. The SenSight Di...

Cannabis for Pain? An Expert's Guidance
https://www.medscape.com/viewarticle/943346

Jan 5th, 2021 - Mark Steven Wallace, MD Many have put forth medical cannabis as a promising treatment for chronic pain that can potentially replace opioids. However, although it's never been easier for patients to access medical cannabis, those researching its us...

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Patient Education  5 results see all →