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About 17,138 results

ALLMedicine™ Intellectual Disability Center

Research & Reviews  6,611 results

Analysis of global prevalence of mental and substance use disorders within countries: f...
https://doi.org/10.1080/09540261.2022.2040450
International Review of Psychiatry (Abingdon, England); Castaldelli-Maia JM, Bhugra D

May 19th, 2022 - This report presents the prevalence of mental and substance use disorders around the world discussing the impact of geographical, sociodemographic, and income characteristics on national epidemiological differences. We analysed data from the Insti...

Human KCNQ5 de novo Mutations Underlie Epilepsy and Intellectual Disability.
https://doi.org/10.1152/jn.00509.2021
Journal of Neurophysiology; Wei AD, Wakenight P et. al.

May 19th, 2022 - We identified six novel de novo human KCNQ5 variants in children with motor/language delay, intellectual disability (ID) and/or epilepsy by whole-exome sequencing. These variants comprised of two nonsense and four missense alterations, were functi...

Ten years of tracking mental health in refugee primary health care settings: an updated...
https://doi.org/10.1186/s12916-022-02371-8 10.1016/S0140-6736(19)30934-1 10.1016/S0140-6736(11)60050-0 10.1001/jama.2009.1132 10.1016/S0140-6736(17)32154-2 10.1002/wps.20438 10.1111/j.1528-1167.2009.02481.x 10.1007/s00415-011-6248-x 10.2471/BLT.09.064147 10.1016/S0140-6736(09)61253-8 10.1001/archpsyc.65.10.1205 10.1186/s12888-016-1166-1 10.1016/j.psychres.2020.112898 10.1111/j.1467-7717.2011.01261.x 10.1371/journal.pone.0159134 10.1002/wps.20808 10.1002/wps.20818 10.1192/S2056474000001392 10.4103/INTV.INTV_14_19 10.4103/INTV.INTV_34_19 10.1016/S2215-0366(15)00097-8 10.2471/BLT.09.074096 10.4103/INTV.INTV_66_18 10.1186/s12916-014-0228-9 10.1093/ije/dyt191 10.1002/pnp.546 10.26719/2015.21.7.498 10.1186/s13033-020-00416-0 10.1186/s13033-019-0312-9 10.1186/s13033-019-0330-7 10.1186/1752-1505-7-3 10.1016/j.jad.2013.06.022 10.1186/s12991-018-0205-3 10.1186/1752-4458-5-5 10.1017/S2045796019000192 10.1371/journal.pmed.1001757 10.1371/journal.pone.0252982 10.1016/S2214-109X(19)30504-2 10.1186/s12888-021-03645-w 10.2471/BLT.18.225086 10.1111/add.12869 10.1097/00005053-199802000-00007 10.1007/978-3-319-72914-5_6 10.1016/S2215-0366(19)30511-5 10.1371/journal.pmed.1003949 10.7202/1073219ar
BMC Medicine; Fine SL, Kane JC et. al.

May 16th, 2022 - This study examines mental, neurological, and substance use (MNS) service usage within refugee camp primary health care facilities in low- and middle-income countries (LMICs) by analyzing surveillance data from the United Nations High Commissioner...

Development and psychometric evaluation of Sexual and Reproductive Health Assessment Sc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107694
BMC Women's Health; Ebadi A, Taghizadeh Z et. al.

May 16th, 2022 - Women with Intellectual disability have many problems in their sexual and reproductive health due to their special mental and physical conditions caused by disability. This study aimed to develop and evaluate the psychometric properties of Sexual ...

Deciphering complex rearrangements at the breakpoint of an apparently balanced reciproc...
https://doi.org/10.1002/ajmg.a.62777
American Journal of Medical Genetics. Part A; Yamada M, Suzuki H et. al.

May 15th, 2022 - When a de novo balanced reciprocal translocation is identified in patients with multiple congenital abnormalities, attempts are often made to infer the relationship between the phenotype of the patient and genes in the proximity of the breakpoint....

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Guidelines  7 results

Practice Parameter for the Assessment and Treatment of Psychiatric Disorders in Childre...
https://doi.org/10.1016/j.jaac.2019.11.018
Journal of the American Academy of Child and Adolescent P... Siegel M, McGuire K et. al.

May 1st, 2021 - Intellectual disability (intellectual developmental disorder) (ID/IDD) is both a psychiatric disorder and a risk factor for co-occurring psychiatric disorders in children and adolescents. DSM-5 introduced important changes in the conceptualization...

Consensus guidelines for the diagnosis and management of pyridoxine-dependent epilepsy ...
https://doi.org/10.1002/jimd.12332
Journal of Inherited Metabolic Disease; Coughlin CR, Tseng LA et. al.

Nov 18th, 2020 - Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an autosomal recessive condition due to a deficiency of α-aminoadipic semialdehyde dehydrogenase, which is a key enzyme in lysine oxidation. PDE-ALDH7A1 is a developmental and epileptic encephalopathy...

ACMG Standards and Guidelines for constitutional cytogenomic microarray analysis, inclu...
https://doi.org/10.1038/gim.2013.129
Genetics in Medicine : Official Journal of the American C... South ST, Lee C et. al.

Sep 28th, 2013 - Microarray methodologies, including array comparative genomic hybridization and single-nucleotide polymorphism-detecting arrays, are accepted as an appropriate first-tier test for the evaluation of imbalances associated with intellectual disabilit...

International consensus clinical practice statements for the treatment of neuropsychiat...
https://doi.org/10.1111/j.1528-1167.2011.03276.x
Epilepsia Kerr MP, Mensah S et. al.

Oct 1st, 2011 - In order to address the major impact on quality of life and epilepsy management caused by associated neuropsychiatric conditions, an international consensus group of epileptologists met with the aim of developing clear evidence-based and practice-...

American College of Medical Genetics standards and guidelines for interpretation and re...
https://doi.org/10.1097/GIM.0b013e3182217a3a
Genetics in Medicine : Official Journal of the American C... Kearney HM, Thorland EC et. al.

Jun 18th, 2011 - Genomic microarrays used to assess DNA copy number are now recommended as first-tier tests for the postnatal evaluation of individuals with intellectual disability, autism spectrum disorders, and/or multiple congenital anomalies. Application of th...

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Clinicaltrials.gov  60 results

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
https://clinicaltrials.gov/ct2/show/NCT02890342

May 13th, 2022 - Propionic acidemia (PA) is one of the most common inborn errors of organic acid metabolism. Although this disorder is now routinely detected in the immediate neonatal period on the US newborn screen, clinical outcomes are poor despite timely and a...

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program
https://clinicaltrials.gov/ct2/show/NCT05368038

May 10th, 2022 - Soon after birth, all babies born in the United States have a newborn screening (NBS) test to check for certain medical conditions. All babies are screened, even if they appear healthy, because most of these conditions have no obvious physical fin...

School-based Physical Activity Intervention for Obesity Among Adolescents With Intellectual Disability in Hong Kong
https://clinicaltrials.gov/ct2/show/NCT04463069

May 9th, 2022 - Background: Children with intellectual disability (ID) might be more vulnerable to obesity than their counterparts in the general population. This study aimed to evaluate the effectiveness of an adapted physical activity (APA) program in reducing ...

Genome Sequencing Strategies for Genetics Diagnosis of Patients With Intellectual Disability
https://clinicaltrials.gov/ct2/show/NCT04154891

May 6th, 2022 - Introduction : Intellectual Disability (ID) is the most common cause of referral in the pediatric genetic centers and is characterized by an extreme genetic heterogeneity corresponding to a myriad of rare diseases that complicates the identificati...

Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities
https://clinicaltrials.gov/ct2/show/NCT05301361

Mar 29th, 2022 - This study is a randomized, double-blind, placebo-controlled, crossover trial of extended-release liquid methylphenidate (XRMPH) to evaluate the sensitivity of the NIH Toolbox Cognition Battery (NIHTB-CB) to changes in cognition in children and ad...

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News  174 results

Novel Drug Offers New Hope for Rett Syndrome
https://www.medscape.com/viewarticle/971720

Apr 6th, 2022 - Trofinetide (Acadia Pharmaceuticals) is effective in improving symptoms in girls and young women with Rett syndrome (RTT), a rare and devastating neurodevelopmental disorder, results from a phase 3 study suggest. Dr Jeffrey Neul "In a severe disor...

AHA/ASA Statement on Acute Stroke Care for Adults With Disability or Dementia
https://www.medscape.com/viewarticle/971115

Mar 29th, 2022 - Adults with pre-existing dementia or disability who suffer acute ischemic stroke can benefit from endovascular therapy (EVT) or thrombolysis, the American Heart Association (AHA)/American Stroke Association (ASA) says in a scientific statement rel...

FDA Okays New Med for Lennox-Gastaut Syndrome
https://www.medscape.com/viewarticle/971158

Mar 29th, 2022 - The US Food and Drug Administration (FDA) has approved fenfluramine (Fintepla) oral solution, a Schedule IV controlled substance, for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in children aged 2 years and older, the c...

Inherited Intellectual Disability in Children Increases Neuropsychiatric Risk
https://www.medscape.com/viewarticle/968867

Feb 18th, 2022 - The study covered in this summary was published on SSRN.com as a preprint and has not yet been peer reviewed. Key Takeaway Children with intellectual disability with a genetic origin have an enhanced risk for developing neuropsychiatric disorders ...

ENTs Discourage Ear Tubes for Recurrent AOM Without Effusion
https://www.medscape.com/viewarticle/968618

Feb 16th, 2022 - A practice guideline update from the ENT community on tympanostomy tubes in children reaffirms that tube insertion should not be considered in cases of otitis media with effusion (OME) lasting less than 3 months, or in children with recurrent acut...

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Patient Education  3 results see all →