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About 6,223 results

ALLMedicine™ Meningioma Center

Research & Reviews  2,394 results

Intracranial necrotising sarcoid granulomatosis mimicking petroclival meningioma.
https://doi.org/10.1136/bcr-2021-247792
BMJ Case Reports; Valappil A, Sundar S S et. al.

May 18th, 2022 - We present a unique case of biopsy-proven necrotising sarcoidosis involving the central nervous system in a man in his 40s. The patient presented with a 2-week history of right-sided headache and diplopia. He had right trochlear and abducens nerve...

Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy
https://clinicaltrials.gov/ct2/show/NCT04082520

May 17th, 2022 - PRIMARY OBJECTIVES: I. To estimate the efficacy of lutetium Lu 177 dotatate (LUTATHERA) treatment in patients with recurrent grade 1 meningioma as measured by 6-month progression-free survival (PFS) rate. II. To estimate the efficacy of LUTATHERA ...

Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic im...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107722
Acta Neuropathologica Communications; Teranishi Y, Okano A et. al.

May 16th, 2022 - NF2 alteration is the most commonly-found genetic abnormality in meningiomas and is known to initiate events for aggressive-type meningiomas. Whereas the prognosis of meningiomas differs depending on their epigenomic/transcriptomic profile, the ef...

Primary Extradural Ectopic Orbital Meningioma in a Child.
https://doi.org/10.1097/IOP.0000000000002200
Ophthalmic Plastic and Reconstructive Surgery; Tynan D, Ng J et. al.

May 14th, 2022 - The authors describe a rare case of primary extradural ectopic meningioma of the orbit in a 13-year-old female managed with surgical excision, adding to the very limited literature of this diagnosis in children. This is the second case to show a r...

Transcriptomic Profiling Revealed Lnc-GOLGA6A-1 as a Novel Prognostic Biomarker of Meni...
https://doi.org/10.1227/neu.0000000000002026
Neurosurgery Slavik H, Balik V et. al.

May 14th, 2022 - Meningioma is the most common primary central nervous system neoplasm, accounting for about a third of all brain tumors. Because their growth rates and prognosis cannot be accurately estimated, biomarkers that enable prediction of their biological...

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Guidelines  1 results

Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: Intern...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566438
Neurosurgery Marchetti M, Sahgal A et. al.

May 29th, 2020 - Stereotactic radiosurgery (SRS) for benign intracranial meningiomas is an established treatment. To summarize the literature and provide evidence-based practice guidelines on behalf of the International Stereotactic Radiosurgery Society (ISRS). Ar...

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Clinicaltrials.gov  36 results

Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy
https://clinicaltrials.gov/ct2/show/NCT04082520

May 17th, 2022 - PRIMARY OBJECTIVES: I. To estimate the efficacy of lutetium Lu 177 dotatate (LUTATHERA) treatment in patients with recurrent grade 1 meningioma as measured by 6-month progression-free survival (PFS) rate. II. To estimate the efficacy of LUTATHERA ...

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma
https://clinicaltrials.gov/ct2/show/NCT02282917

May 11th, 2022 - This is a multi-center, proof of concept phase 0 study to assess the suppression of p-AKT in VS and meningiomas by AR-42 in adult patients undergoing NF2-tumor resection. AR-42 will be administered three times per week beginning 3 weeks prior to s...

Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma
https://clinicaltrials.gov/ct2/show/NCT02847559

Apr 22nd, 2022 - PRIMARY OBJECTIVES: I. To determine progression free survival (PFS) for 6 months (PFS-6) in patients with recurrent or progressive meningioma. SECONDARY OBJECTIVES: I. To determine overall survival (OS). II. To determine tumor response rate (TRR)....

Gleolan for Visualization of Newly Diagnosed or Recurrent Meningioma
https://clinicaltrials.gov/ct2/show/NCT04305470

Apr 20th, 2022 - This Phase 3 open-label single-arm study is designed to investigate the safety, diagnostic performance, and clinical usefulness of the imaging agent Gleolan™ (Aminolevulinic Acid Hydrochloride, ALA HCl, ALA, 5-ALA), an orally administered imaging ...

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
https://clinicaltrials.gov/ct2/show/NCT02523014

Apr 19th, 2022 - PRIMARY OBJECTIVES: I. To determine the activity of a SMO inhibitor in patients with meningiomas harboring SMO and PTCH1 mutations as measured by 6-month progression free survival (PFS) and response rate. II. To determine the activity of a FAK inh...

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News  50 results

Brain Tumors Exact Higher Mortality Toll in Men Than Women
https://www.medscape.com/viewarticle/968594

Feb 15th, 2022 - New research shows that men in their 20s and 30s have worse survival from many different types of brain tumors than women of the same age. And, researchers say, it’s not exactly clear why. Differences in treatment may mediate some of the associati...

GI Cancer and Obesity: Fighting One Means Addressing the Other
https://www.medscape.com/viewarticle/959973

Oct 6th, 2021 - By 2030, it is projected that most Americans will be overweight, and of those, nearly 50% of adults will be obese. Although the majority of Americans are aware that obesity can have adverse health consequences, survey findings show that few are aw...

Increased Risk of Meningioma With Cyproterone Acetate Use
https://www.medscape.com/viewarticle/945218

Feb 3rd, 2021 - New details confirm an increased risk of developing intracranial meningiomas after prolonged use of the hormonal product cyproterone acetate. Cyproterone acetate is a synthetic progestogen and potent anti-androgen that has been used in the treatme...

Meningioma May Be Tied to Dental X-Rays
https://www.onclive.com/view/meningioma-may-be-tied-to-dental-x-rays

Dec 5th, 2020 - Elizabeth B. Claus, MD New data suggest that dental x-rays obtained frequently at a young age may boost the risk of intracranial meningioma. Although dental x-rays are an important tool in well selected patients, efforts to moderate exposure to ...

Direct Targeting of RET Aberrations Moves Closer to the Clinic
https://www.onclive.com/view/direct-targeting-of-ret-aberrations-moves-closer-to-the-clinic

Dec 5th, 2020 - Alexander Drilon, MD Research on the proto-oncogene RET has accelerated exponentially since 1985, when Masahide Takahashi, MD, PhD, and colleagues first reported a fusion rearrangement in lymphoma DNA.1 Early progress was slow. Other investigator...

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Patient Education  8 results see all →