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About 7,240 results

ALLMedicine™ Microcephaly Center

Research & Reviews  2,506 results

Opsin 3 Regulates Melanogenesis in Human Congenital Melanocytic Nevus Cells via Functio...
https://doi.org/10.1016/j.jid.2022.04.022
The Journal of Investigative Dermatology; Dong X, Zeng W et. al.

May 17th, 2022 - Opsin3 (OPN3), as a member of the opsin family, has various non-light dependent functions. Congenital melanocytic nevus (CMN) is a skin lesion with dark pigmentation that appears at birth and can be initiated by the BRAFV600E mutation in melanocyt...

Early childhood neurodevelopmental outcomes in children with prenatal Zika virus exposu...
https://doi.org/10.1016/j.jpeds.2022.05.016
The Journal of Pediatrics; Alvarado-Domenech LI, Rivera-Amill V et. al.

May 17th, 2022 - To describe anthropometric, sensory, and neurodevelopmental outcomes of Zika virus exposed children from birth to 36 months. The cohort includes 114 children born to mothers with confirmed and probable ZIKV pregnancy infection, from 2016-2017. Chi...

Implications for quantifying early life growth trajectories of term-born infants using ...
https://doi.org/10.1111/ppe.12880
Paediatric and Perinatal Epidemiology; Perumal N, Ohuma EO et. al.

May 17th, 2022 - The INTERGROWTH-21st sex and gestational age (GA) specific newborn size standards (IG-NS) are intended to complement the World Health Organization Child Growth Standards (WHO-GS), which are not GA-specific. We examined the implications of using IG...

Ocular findings of congenital Zika virus infection with microcephaly.
https://doi.org/10.1007/s10792-022-02311-8 10.1093/infdis/jix396 10.1016/0035-9203(52)90042-4 10.1016/0035-9203(52)90043-6 10.3201/eid2006.140138 10.1590/0074-02760150192 10.1016/S0140-6736(16)00006-4 10.1016/S0140-6736(16)30776-0 10.1001/jamapediatrics.2017.1474 10.1016/S0140-6736(17)31368-5 10.1001/jamapediatrics.2016.3982 10.3201/eid2211.160956 10.1016/j.survophthal.2017.06.001 10.1136/bmj.i3899 10.1016/S0140-6736(14)60932-6 10.1097/QCO.0000000000000301 10.1056/NEJMc1606769 10.15585/mmwr.rr6801a1 10.1126/science.aaf8505 10.1016/S0140-6736(17)31450-2 10.1016/S2352-4642(18)30020-8 10.1590/0037-8682-0105-2019 10.1016/S1473-3099(20)30021-9 10.15585/mmwr.mm6512e2 10.2471/BLT.17.201541 10.1093/cid/ciy261 10.1016/j.ajog.2017.01.020 10.4269/ajtmh.18-0237 10.1016/j.socscimed.2020.112787 10.1111/dmcn.12425 10.1186/1471-2431-13-59 10.1016/S0140-6736(16)00273-7 10.1001/jamaophthalmol.2016.1784 10.1016/S1473-3099(16)00095-5 10.5935/0004-2749.20160112 10.1097/ICB.0000000000000518 10.1097/IJG.0000000000001150 10.1001/jamaophthalmol.2016.0267 10.1016/j.ophtha.2016.10.004 10.1016/j.ophtha.2017.06.009 10.1001/jamaophthalmol.2017.3595 10.1186/s13256-018-1679-y 10.1016/j.ophtha.2016.05.001 10.1590/1806-9282.65.6.909 10.1542/peds.2018-1104 10.1155/2020/7092432 10.3928/23258160-20161004-09 10.5935/0004-2749.20160002 10.1001/jamaophthalmol.2016.4283 10.1016/j.jaapos.2017.05.024 10.1001/jamaophthalmol.2017.0561 10.1128/mSphere.00173-19 10.1097/IJG.0000000000001253 10.1111/joim.12829 10.1016/j.jaapos.2017.04.003 10.1001/jamaophthalmol.2017.3292 10.1159/000308996 10.1212/WNL.0000000000005950 10.1111/aos.12759
International Ophthalmology; Costa CBDC, Freitas D

May 16th, 2022 - To describe ocular findings in infants with signs of congenital Zika virus syndrome (CZS) in Paraíba, Brazil, as well as to conduct a literature review and report correlations with published clinical cases. In the Paraíba sample, infants with micr...

Deciphering the molecular landscape of microcephaly in 87 Indian families by exome sequ...
https://doi.org/10.1016/j.ejmg.2022.104520
European Journal of Medical Genetics; Masih S, Moirangthem A et. al.

May 15th, 2022 - Microcephaly is a frequent feature of neurodevelopmental disorders (NDDs). Our study presents the heterogeneous spectrum of genetic disorders in patients with microcephaly either in isolated form or in association with other neurological and extra...

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Guidelines  5 results

No. 380-Investigation and Management of Prenatally Identified Microcephaly.
https://doi.org/10.1016/j.jogc.2018.10.014
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... De Bie I, Boucoiran I

May 28th, 2019 - To update Canadian maternity care and reproductive health care providers on the diagnostic criteria of fetal microcephaly and provide information on the relevant investigations, prognosis, and pre- and perinatal management of this prenatal finding...

No. 240-Cytomegalovirus Infection in Pregnancy.
https://doi.org/10.1016/j.jogc.2017.11.018
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Yinon Y, Farine D et. al.

Feb 16th, 2018 - To review the principles of prenatal diagnosis of congenital cytomegalovirus (CMV) infection and to describe the outcomes of the affected pregnancies. Effective management of fetal infection following primary and secondary maternal CMV infection d...

Congenital microcephaly: Case definition & guidelines for data collection, analysis, an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710988
Vaccine DeSilva M, Munoz FM et. al.

Nov 19th, 2017 - Congenital microcephaly: Case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation.|2017|DeSilva M,Munoz FM,Sell E,Marshall H,Tse Kawai A,|standards,standards,epidemiology,adverse effects,

Toxoplasmosis in pregnancy: prevention, screening, and treatment.
https://www.ncbi.nlm.nih.gov/pubmed/23343802
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Paquet C, Yudin MH et. al.

Jan 25th, 2013 - One of the major consequences of pregnant women becoming infected by Toxoplasma gondii is vertical transmission to the fetus. Although rare, congenital toxoplasmosis can cause severe neurological or ocular disease (leading to blindness), as well a...

Practice parameter: Evaluation of the child with microcephaly (an evidence-based review...
https://doi.org/10.1212/WNL.0b013e3181b783f7
Neurology Ashwal S, Michelson D et. al.

Sep 16th, 2009 - To make evidence-based recommendations concerning the evaluation of the child with microcephaly. Relevant literature was reviewed, abstracted, and classified. RECOMMENDATIONS were based on a 4-tiered scheme of evidence classification. Microcephaly...

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Drugs  6 results see all →

Clinicaltrials.gov  11 results

Eltrombopag for People With Fanconi Anemia
https://clinicaltrials.gov/ct2/show/NCT03206086

May 13th, 2022 - Fanconi anemia (FA) is a rare genetic disease that often presents as a bone marrow failure (BMF) syndrome but also can affect any other organ. Etiologically, loss of function mutations in more than 21 different gene members of the FA core complex ...

Summary of Infants Weighing 500 Grams or Less
https://clinicaltrials.gov/ct2/show/NCT05322980

May 5th, 2022 - This is a retrospective single-center cohort study. The study setting is a level IV neonatal intensive care unit (NICU) at Nagano Children's Hospital in Nagano, Japan. We will retrospectively collect the data of those who were admitted to Nagano C...

Neurologic Manifestations of COVID 19 in Children
https://clinicaltrials.gov/ct2/show/NCT04379089

Mar 31st, 2022 - Early reports of COVID-19 indicate that adults experience a variety of neurological symptoms and diagnoses in approximately 36% of patients, including headaches, seizures, coma, encephalitis, and cerebrovascular events including ischemic stroke, i...

Neuro-COVID-19: Neurological Complications of COVID-19
https://clinicaltrials.gov/ct2/show/NCT04418609

Nov 3rd, 2021 - This study is a prospective observational cohort study to document prevalence and severity of neurological symptoms among patients requiring critical care admission for confirmed novel coronavirus disease (COVID-19). COVID-19 is classified as seve...

Metabolic Study of Cockayne Syndrome
https://clinicaltrials.gov/ct2/show/NCT03044210

Sep 14th, 2021 - Cockayne syndrome (CS) is related to defective DNA transcription and/or repair and belongs to the family of Nucleotide Excision Repair. It is an autosomal recessive multisystemic disorder characterized by mental retardation, microcephaly, severe g...

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News  365 results

Mortality 12 Times Higher in Children With Congenital Zika
https://www.medscape.com/viewarticle/969022

Feb 23rd, 2022 - About 80% of people infected with Zika virus show no symptoms, and that's particularly problematic during pregnancy. The infection can cause birth defects and is the origin of numerous cases of microcephaly and other neurologic impairments. The la...

India's Latest Zika Outbreak Sees Surge of Nearly 100 Cases
https://www.medscape.com/viewarticle/962495

Nov 9th, 2021 - (Reuters) - At least 89 people, including 17 children, have tested positive for the Zika virus in a surge of cases in the Indian city of Kanpur, its health department said on Monday. First discovered in 1947, the mosquito-borne virus Zika virus re...

To Study Zika, They Offered Their Kids. Then They Were Forgotten.
https://www.medscape.com/viewarticle/960362

Oct 6th, 2021 - Rochelle dos Santos embraces her daughter, who was born with microcephaly in 2016 after dos Santos contracted Zika during her pregnancy in midwest Brazil. Rochelle Dos Santos learned that her daughter would probably be born with microcephaly — a c...

As Zika-Affected Babies Grow, Developmental Outcomes Vary
https://www.medscape.com/viewarticle/958796

Sep 16th, 2021 - NEW YORK (Reuters Health) - At age 2 years and beyond, babies born with microcephaly after exposure to Zika virus in the womb often have more severe neurodevelopmental delays and slower growth rates than their peers, although neurodevelopmental pr...

Three genes could predict congenital Zika infection susceptibility
https://www.mdedge.com/pediatrics/article/233277/infectious-diseases/three-genes-could-predict-congenital-zika-infection
Sarah Stinnissen, MA

Dec 9th, 2020 - Three genes that could predict susceptibility to congenital Zika virus (ZIKV) infection have been identified, Dr. Irene Rivero-Calle, MD, shared at the annual meeting of the European Society for Paediatric Infectious Diseases, held virtually this.

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Patient Education  3 results see all →