ALLMedicine™ Neurofibromatosis Type 1 Center
Research & Reviews 1,389 results
https://doi.org/10.1186/s13023-022-02356-z 10.1038/nrdp.2017.4 10.1002/ajmg.a.38680 10.1111/dmcn.13526 10.1002/ajmg.a.61627 10.1017/S0012162201001876 10.1542/peds.2013-1868 10.1016/j.yebeh.2019.04.027 10.1097/MOP.0b013e328305e128 10.1542/peds.2004-1321 10.1136/adc.2010.202473 10.1002/ajmg.a.35982 10.1001/jamapediatrics.2015.3168 10.1002/ajmg.a.35840 10.1016/j.jbi.2008.08.010 10.1016/j.jadohealth.2012.12.014 10.1080/13651501.2021.1895524
Orphanet Journal of Rare Diseases; Lausdahl S, Handrup MM et. al.
May 22nd, 2022 - The transition of adolescents to adult care is known to be challenging. Studies indicate that patients with a chronic disease and cognitive deficits are at risk of inadequate transition to adult care, which eventually may result in disease deterio...
https://doi.org/10.1148/rg.220062
Radiographics : a Review Publication of the Radiological ... Murphy AN, Kearns C
May 21st, 2022 - Gastrointestinal Stromal Tumors and their Appearance in Patients with Neurofibromatosis Type 1.|2022|Murphy AN,Kearns C,|
https://clinicaltrials.gov/ct2/show/NCT01702922
May 20th, 2022 - Background: Parents face numerous stressors when their child is diagnosed with cancer or NF1, each of which can strain a marriage/partnership. Marital/partner relationship dynamics are often not assessed or addressed when providing health care for...
https://clinicaltrials.gov/ct2/show/NCT03531814
May 20th, 2022 - Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that affects approximately 1 in 3,500 individuals and is associated with a broad variety of symptoms and physical findings. Plexiform neurofibromas (PN) are histologically benign tum...
https://clinicaltrials.gov/ct2/show/NCT03739827
May 20th, 2022 - Background: Rare tumors are defined as fewer than 150 incident cases per one million per year. Consequently, only 11 tumor types are common in U.S. adults (prostate, breast, lung/bronchus, colon, uterus, bladder, melanoma, rectum, ovary, non-Hodgk...
Guidelines 4 results
https://doi.org/10.1038/gim.2018.28
Genetics in Medicine : Official Journal of the American C... Stewart DR, Korf BR et. al.
Jul 15th, 2018 - This practice resource is designed primarily as an educational resource for medical geneticists and other clinicians to help them provide quality medical services. Adherence to this practice resource is completely voluntary and does not necessaril...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578356
Neurology Walsh KS, Janusz J et. al.
Aug 17th, 2016 - Neurofibromatosis type 1 (NF1) is associated with neurocognitive deficits that can impact everyday functioning of children, adolescents, and adults with this disease. However, there is little agreement regarding measures to use as cognitive endpoi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578358
Neurology Plotkin SR, Davis SD et. al.
Aug 17th, 2016 - Plexiform neurofibromas (PNs) are complex, benign nerve sheath tumors that occur in approximately 25%-50% of individuals with neurofibromatosis type 1 (NF1). PNs that cause airway compromise or pulmonary dysfunction are uncommon but clinically imp...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578359
Neurology Ahlawat S, Fayad LM et. al.
Aug 17th, 2016 - The Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) International Collaboration Whole-Body MRI (WB-MRI) Working Group reviewed the existing literature on WB-MRI, an emerging technology for assessing disease in patients with ne...
Drugs 1 results see all →
Clinicaltrials.gov 35 results
https://clinicaltrials.gov/ct2/show/NCT03531814
May 20th, 2022 - Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that affects approximately 1 in 3,500 individuals and is associated with a broad variety of symptoms and physical findings. Plexiform neurofibromas (PN) are histologically benign tum...
https://clinicaltrials.gov/ct2/show/NCT04488263
May 20th, 2022 - Background: Neuroendocrine neoplasm (NENs) are divided into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). These are rare malignancies occurring for example in the gastrointestinal tract, islets of the pancreas, lung, adrenal m...
https://clinicaltrials.gov/ct2/show/NCT01702922
May 20th, 2022 - Background: Parents face numerous stressors when their child is diagnosed with cancer or NF1, each of which can strain a marriage/partnership. Marital/partner relationship dynamics are often not assessed or addressed when providing health care for...
https://clinicaltrials.gov/ct2/show/NCT03739827
May 20th, 2022 - Background: Rare tumors are defined as fewer than 150 incident cases per one million per year. Consequently, only 11 tumor types are common in U.S. adults (prostate, breast, lung/bronchus, colon, uterus, bladder, melanoma, rectum, ovary, non-Hodgk...
https://clinicaltrials.gov/ct2/show/NCT02407405
May 20th, 2022 - Background: Neurofibromatosis 1 (NF1) is an autosomal dominant disorder with an incidence of 1:3500 in the US. One of the cardinal features of NF1 is the development of histologically benign peripheral nervesheath tumors called plexiform neurofibr...
News 33 results
https://www.onclive.com/view/dr-trent-on-the-utility-of-ctdna-to-understand-primary-mutations-in-gist
Oct 6th, 2021 - Jonathan C. Trent, MD, PhD, professor and associate director for Clinical Research at the Sylvester Comprehensive Cancer Center, University of Miami Health System, discusses the utility of circulating tumor DNA (ctDNA) to understand primary driver...
https://www.medscape.com/viewarticle/958224
Sep 6th, 2021 - A novel liquid biopsy test has been shown to distinguish between patients with neurofibromatosis type 1 (NF1) who have benign plexiform neurofibroma (PN) precursor lesions from patients who have malignant peripheral nerve sheath tumors (MPNST), sa...
https://www.medscape.com/viewarticle/955499
Jul 27th, 2021 - When a child presents with café au lait macules, when is genetic testing for neurofibromatosis type 1 (NF1) advised? According to Peter Kannu, MB, ChB, DCH, PhD, a definitive diagnosis of NF1 can be made in most children using National Institutes ...
https://www.onclive.com/view/selumetinib-approved-in-europe-for-pediatric-neurofibromatosis-type-1-and-plexiform-neurofibromas
Jun 22nd, 2021 - The European Commission has granted a conditional approval to selumetinib (Koselugo) for the treatment of pediatric patients with symptomatic, inoperable plexiform neurofibromas (PN) and neurofibromatosis type 1 (NF1) who are at least 3 years of a...
https://www.onclive.com/view/surge-of-new-drugs-fuels-optimism-in-pediatric-oncology
Feb 4th, 2021 - The landscape for pediatric oncology drugs expanded dramatically last year, with 8 new drugs or indications specifically approved for children compared with just 47 for treatment and supportive care products from the early 1950s through 2019.1,2 ...