About 2,193 results

ALLMedicine™ Progressive Supranuclear Palsy Center

Research & Reviews  849 results

Relationship between 18F-flortaucipir uptake and histologic lesion types in 4-repeat ta...
Journal of Nuclear Medicine : Official Publication, Socie... Josephs K, Tosakulwong N et. al.

Sep 25th, 2021 - Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are 4-repeat tauopathies with overlapping, but also morphologically distinct tau immunoreactive lesions that vary in count by brain region. 18F-flortaucipir positron emission...

Distinct phosphorylation profiles of tau in brains of patients with different tauopathies.
Neurobiology of Aging; Samimi N, Sharma G et. al.

Sep 19th, 2021 - Tauopathies are neurodegenerative diseases that are characterized by pathological accumulation of tau protein. Tau is hyperphosphorylated in the brain of tauopathy patients, and this phosphorylation is proposed to play a role in disease developmen...

Midbrain area and the hummingbird sign from brain MRI in progressive supranuclear palsy...
Journal of Neuroimaging : Official Journal of the America... Virhammar J, Blohmé H et. al.

Sep 15th, 2021 - The main radiological finding in progressive supranuclear palsy (PSP) is reduced midbrain volume. Both qualitative (e.g., hummingbird sign) and quantitative (e.g., area measurements) markers have been noted. Recent studies have shown a similar red...

Alzheimer's Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-Derive...
Current Molecular Pharmacology; Durairajan SSK, Selvarasu K et. al.

Sep 8th, 2021 - Alzheimer's disease (AD), a major form of dementia, has been reported to affect more than 50 million people worldwide. It is characterized by the presence of amyloid-β (Aβ) plaques and hyperphosphorylated Tau-associated neurofibrillary tangles in ...

Laboratory based assessment of gait and balance impairment in patients with progressive...
Journal of the Neurological Sciences; Ali F, Loushin SR et. al.

Aug 31st, 2021 - Gait and balance abnormalities are a significant source of morbidity and mortality in progressive supranuclear palsy (PSP). Gait impairment in PSP is primarily assessed clinically on exam or with the use of rating scales. Three dimensional video b...

see more →

Drugs  1 results see all →

News  26 results

Negative Phase 2 Trial Data Ends Development of PSP Drug

Dec 13th, 2019 - Topline results from the phase two PASSPORT trial show the experimental drug gosuranemab (BIIB092, Biogen) did not meet its primary or key secondary endpoints in patients with the atypical parkinsonian disorder of progressive supranuclear palsy (P...

The Falls and Frustrations of Progressive Supranuclear Palsy

Nov 25th, 2019 - I often repeat her presentation to medical students: my only patient ever to fall walking into a clinic visit had progressive supranuclear palsy (PSP). Her impaired postural reflexes were no match for a set of brick steps. Perhaps she didn't notic...

How Accurately Do Current Criteria Identify CBD and PSP?

Aug 2nd, 2018 - LOS ANGELES—Current criteria are comparatively insensitive and nonspecific for distinguishing between corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), according to research presented at the 70th Annual Meeting of the Ameri.

Blink Reflex Recovery Cycle Distinguishes Progressive Supranuclear Palsy From Corticobasal Degeneration

Oct 12th, 2017 - KYOTO, Japan — The R2 component of the blink reflex recovery cycle (R2 BRRC) appears to be a useful tool to distinguish progressive supranuclear palsy (PSP) from corticobasal degeneration (CBD) with high sensitivity and specificity when the differ...

CurePSP International Research Symposium to Take Place in San Francisco
Neurology Reviews;

Sep 27th, 2017 - CurePSP (Progressive Supranuclear Palsy) will host an international research symposium at the Mission Bay Conference Center at UCSF in San Francisco on Oct. 26-27, 2017.

see more →

Patient Education  1 results see all →