ALLMedicine™ Spinocerebellar Ataxia Center
Research & Reviews 1,071 results
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107762
Journal of Translational Medicine; Peng L, Peng Y et. al.
May 16th, 2022 - In polyglutamine (polyQ) diseases, the identification of modifiers and the construction of prediction model for progression facilitate genetic counseling, clinical management and therapeutic interventions. Data were derived from the longest longit...
https://doi.org/10.1093/cercor/bhac199
Cerebral Cortex (New York, N.Y. : 1991); Tang J, Xie Y et. al.
May 15th, 2022 - Gray matter volume and thickness reductions have been reported in patients with spinocerebellar ataxia type 3 (SCA3), whereas cortical gyrification alterations of this disease remain largely unexplored. Using local gyrification index (LGI) and fra...
https://doi.org/10.1055/a-1849-8128
Neuropediatrics Benevides ML, França M
May 12th, 2022 - Spinocerebellar ataxia type 5 (SCA5) is a rare subtype of SCA that usually affects adults. It has been recently reported in children in Europe, North America, and China. This study aims to describe clinical, radiological, and genetic data of a chi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029677
Tremor and Other Hyperkinetic Movements (New York, N.Y.); Ganaraja VH, Holla VV et. al.
May 10th, 2022 - Spinocerebellar ataxia type-12 (SCA12) is a rare form of SCA, most commonly reported from the Indian Agarwal and related families. In this study we describe the clinical, genetic, and radiological characteristics of a sizeable cohort of geneticall...
https://clinicaltrials.gov/ct2/show/NCT03378414
May 9th, 2022 - This is a random, open label, and parallel controled experiment. 45 patients are selected and sign consent forms, then divided into three groups. Doctors collect the basic information of patient (including age,height, mental condition, vital sign,...
Clinicaltrials.gov 15 results
https://clinicaltrials.gov/ct2/show/NCT03378414
May 9th, 2022 - This is a random, open label, and parallel controled experiment. 45 patients are selected and sign consent forms, then divided into three groups. Doctors collect the basic information of patient (including age,height, mental condition, vital sign,...
https://clinicaltrials.gov/ct2/show/NCT03885167
Feb 11th, 2022 - Participants will undergo a SARA exam, a lumbar puncture and a blood draw. A lumbar puncture is a procedure in which a small amount of the spinal fluid that surrounds the brain and spinal cord is removed by inserting a needle in the lower back. Pa...
https://clinicaltrials.gov/ct2/show/NCT03487367
Jan 19th, 2022 - Spinocerebellar ataxia types 1 (SCA1) and 3 (SCA3) are rare, inherited neurodegenerative disorders that relentlessly progress to total disability and death. SCA1 is the fastest progressing SCA while SCA3 is the most common SCA in US and Europe. Ex...
https://clinicaltrials.gov/ct2/show/NCT04529252
Oct 14th, 2021 - The investigators are initiating a new program dedicated to the research and study of neurodegenerative forms of spinocerebellar ataxia as well and other nucleotide repeat diseases with the exclusion of Huntington's Disease. The analysis will be c...
https://clinicaltrials.gov/ct2/show/NCT04399265
Dec 9th, 2020 - Spinocerebellar ataxia 3 (SCA3) is a rare form of inherited neurodegenerative disease involving progressive degeneration of spinocerebellar tract. SCA3 is characterised by increasingly worsening cerebellar function leading to gait abnormalities an...
News 6 results
https://www.medscape.com/viewarticle/943249
Jan 5th, 2021 - A patient asks an advanced practice registered nurse (APRN) to approve them for "medical marijuana." What are the clinician's responsibilities? The first hurdle is legal. In 18 states, an APRN has the legal authority to certify a patient to use ma...
https://www.mdedge.com/neurology/article/141127/movement-disorders/neurologists-review-data-treatments-spinocerebellar
Jun 23rd, 2017 - MIAMI—Advances in genetic testing have enabled precise identification of many spinocerebellar ataxias, but no pharmacologic therapy for the disorders has been approved, according to an overview presented at the First Pan American Parkinson’s Disea.
https://www.mdedge.com/familymedicine/article/46776/neurology/discoveries-could-slow-dysfunction-spinocerebellar-ataxia/page/0/1
Internal Medicine News;
Dec 19th, 2011 - Dr. Cvetanovic and her associates found that the expression of the gene for VEGF, an angiogenic and neurotrophic growth factor, was downregulated in the cerebellar Purkinje neurons of SCA1 mice before they showed any behavioral or pathologic signs.
https://www.mdedge.com/neurology/article/48658/neuromuscular-disorders/huntingtons-biomarker-discovery-could-set-tone
Jeff Evans
Nov 1st, 2011 - A biomarker found in the blood of patients with Huntington's disease appears to mark early stages of the disease and measure response to treatment, without confusing signs of Huntington's with those of other neurodegenerative diseases. Yi Hu, Ph.
https://www.medscape.com/viewarticle/750378
Sep 26th, 2011 - September 26, 2011 — Huda Y. Zoghbi, MD, professor of pediatrics, molecular and human genetics, and neurology and neuroscience at Baylor College of Medicine in Houston, Texas, has been named the recipient of the 2011 Gruber Neuroscience Prize. The...