ALLMedicine™ Status Epilepticus Center

May 22nd, 2022 - Ganaxolone (ZTALMY®; Marinus Pharmaceuticals) is a synthetic neuroactive steroid that acts as a positive allosteric modulator of the gamma-aminobutyric acid (GABA)A receptor complex. Ganaxolone received its first approval in March 2022 in the USA ...

May 18th, 2022 - To investigate differences in long-term survival and short-term neurological deficits in adult patients fulfilling either sub-criterion of the Salzburg Consensus Criteria (SC) for non-convulsive status epilepticus (NCSE). We retrospectively identi...

May 17th, 2022 - Bromine compounds are used in several drugs, including over-the-counter drugs. They sometimes cause intoxication known as bromism. Although the acute neurological symptoms and sequelae of bromism vary, few reports have mentioned acute encephalopat...

May 16th, 2022 - Augmentation of neurogenesis and migration of newly born neurons into ectopic regions like the hilus play critical roles during the pathophysiology of acute kindled seizures. Evidence shows that disrupted in schizophrenia 1 (DISC1) has an influenc...

May 12th, 2022 - To evaluate the safety and effectiveness of levetiracetam and phenytoin by evaluating the events of seizure termination and recurrence in children. We used the internet databases PubMed, Embase, and Google Scholar to conduct a literature search fo...

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

Jan 30th, 2015 - Critical Care Continuous EEG (CCEEG) is a common procedure to monitor brain function in patients with altered mental status in intensive care units. There is significant variability in patient populations undergoing CCEEG and in technical specific...

Jan 7th, 2010 - The objective of the current article was to review the literature and discuss the degree of evidence for various treatment strategies for status epilepticus (SE) in adults. We searched MEDLINE and EMBASE for relevant literature from 1966 to Januar...

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including the risk of pregnancy complications or other medical problems during pregnancy in WWE compared to other women, change in se...

May 3rd, 2022 - This is an open-label study consisting of a screening period (1 day), 4-day treatment period (96 hours) followed by a 1-day dose taper period (24 hours), a 2-day acute follow-up period, and a 3 week extended follow-up period. On Day 1 of treatment...

Apr 26th, 2022 - Recently, the pathogenesis of epilepsy is immuno-modulatory and neuro-inflammatory which is commonly activated in epileptogenic brain regions in humans and is clearly involved in animal models of epilepsy. Inflammatory mediators in the blood and m...

Apr 14th, 2022 - The problem under investigation is the reduced functional mobility of patients with Dravet syndrome resulting from a crouch gait pattern. The solution, proposed in this research project, is the development of a decision framework based upon clinic...

Mar 8th, 2022 - The SUrVIS project is structured around a 12-persons one-day interdisciplinary in situ simulation training sessions including: Training in... Recognition of the critically ill child and pediatric cardiopulmonary arrest The call for help according ...

Mar 4th, 2022 - The aim of this observational single-center cohort study is to gain a deeper understanding regarding the effects of treatment adaption based on information from outcome prediction models, risk stratification, as well as treatment monitoring, detec...

Apr 25th, 2022 - NEW YORK (Reuters Health) - In patients with status epilepticus that is "less damaging" to the brain, a three-factor scoring system may help predict post-discharge outcomes, researchers suggest. As reported in JAMA Neurology, Dr. Christoph Beier o...

Mar 10th, 2022 - As neurologists in war-torn Ukraine plead for assistance, professional societies around the world are taking action. "There are children in dire need of their antiseizure medications (ASMs) going into status epilepticus," tweeted pediatric neurolo...

Feb 2nd, 2022 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner reporting on the recent, virtually held American Epilepsy Society meeting. With me today is Dr Charles Szabo, professor and chief of epile...

Dec 13th, 2021 - Patients who experience stroke have a "very high" risk of epilepsy 1 year later, new research shows. Results from a large registry study reveals patients who experienced a severe intracerebral hemorrhage (ICH) had an almost 10% chance of developin...

Nov 17th, 2021 - Prehospital treatment of people with status epilepticus rarely was consistent with expert guidelines, an analysis of emergency medical service (EMS) agency records showed. Initial treatment was concordant with guidelines in only 3.9% of 9,176 EMS ...