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About 8,188 results

ALLMedicine™ Status Epilepticus Center

Research & Reviews  2,983 results

Ganaxolone: First Approval.
https://doi.org/10.1007/s40265-022-01724-0 10.1186/s11689-021-09384-z 10.1016/j.pediatrneurol.2019.02.015 10.1016/S0028-3908(99)00190-2 10.1111/j.1528-1157.2000.tb00244.x 10.1124/jpet.118.252155 10.1016/S1474-4422(22)00077-1 10.1186/s11689-017-9207-8
Drugs Lamb YN

May 22nd, 2022 - Ganaxolone (ZTALMY®; Marinus Pharmaceuticals) is a synthetic neuroactive steroid that acts as a positive allosteric modulator of the gamma-aminobutyric acid (GABA)A receptor complex. Ganaxolone received its first approval in March 2022 in the USA ...

Salzburg consensus criteria are associated with long-term outcome after non-convulsive ...
https://doi.org/10.1016/j.seizure.2022.05.006
Seizure Monsson OS, Roberg LE et. al.

May 18th, 2022 - To investigate differences in long-term survival and short-term neurological deficits in adult patients fulfilling either sub-criterion of the Salzburg Consensus Criteria (SC) for non-convulsive status epilepticus (NCSE). We retrospectively identi...

Bromisoval-induced bromism with status epilepticus mimicking Wernicke's encephalopathy:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109394
BMC Neurology; Biyajima M, Satoh S et. al.

May 17th, 2022 - Bromine compounds are used in several drugs, including over-the-counter drugs. They sometimes cause intoxication known as bromism. Although the acute neurological symptoms and sequelae of bromism vary, few reports have mentioned acute encephalopat...

Disrupted in Schizophrenia 1 Regulates Ectopic Neurogenesis in the Mouse Hilus After Pi...
https://doi.org/10.1016/j.neuroscience.2022.05.009
Neuroscience Chen L, Zhu L et. al.

May 16th, 2022 - Augmentation of neurogenesis and migration of newly born neurons into ectopic regions like the hilus play critical roles during the pathophysiology of acute kindled seizures. Evidence shows that disrupted in schizophrenia 1 (DISC1) has an influenc...

Comparison of Safety and Effectiveness between Levetiracetam and Phenytoin in the Treat...
https://doi.org/10.2174/1568007X04666220509215121
CNS & Neurological Disorders Drug Targets; AlMulihi QA, AlMuhanna FA et. al.

May 12th, 2022 - To evaluate the safety and effectiveness of levetiracetam and phenytoin by evaluating the events of seizure termination and recurrence in children. We used the internet databases PubMed, Embase, and Google Scholar to conduct a literature search fo...

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Guidelines  4 results

ACR Appropriateness Criteria® Seizures-Child.
https://doi.org/10.1016/j.jacr.2021.02.020
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

Consensus statement on continuous EEG in critically ill adults and children, part I: in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435533
Journal of Clinical Neurophysiology : Official Publicatio... Herman ST, Abend NS et. al.

Jan 30th, 2015 - Critical Care Continuous EEG (CCEEG) is a common procedure to monitor brain function in patients with altered mental status in intensive care units. There is significant variability in patient populations undergoing CCEEG and in technical specific...

EFNS guideline on the management of status epilepticus in adults.
https://doi.org/10.1111/j.1468-1331.2009.02917.x
European Journal of Neurology; Meierkord H, Boon P et. al.

Jan 7th, 2010 - The objective of the current article was to review the literature and discuss the degree of evidence for various treatment strategies for status epilepticus (SE) in adults. We searched MEDLINE and EMBASE for relevant literature from 1966 to Januar...

Practice parameter update: management issues for women with epilepsy--focus on pregnanc...
https://doi.org/10.1212/WNL.0b013e3181a6b2f8
Neurology Harden CL, Hopp J et. al.

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including the risk of pregnancy complications or other medical problems during pregnancy in WWE compared to other women, change in se...

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Drugs  80 results see all →

Clinicaltrials.gov  34 results

Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus
https://clinicaltrials.gov/ct2/show/NCT02052739

May 3rd, 2022 - This is an open-label study consisting of a screening period (1 day), 4-day treatment period (96 hours) followed by a 1-day dose taper period (24 hours), a 2-day acute follow-up period, and a 3 week extended follow-up period. On Day 1 of treatment...

Possible Immuno-Modulatory Effect of Tocilizumab in Patients With Refractory Status Epilepticus.
https://clinicaltrials.gov/ct2/show/NCT05346666

Apr 26th, 2022 - Recently, the pathogenesis of epilepsy is immuno-modulatory and neuro-inflammatory which is commonly activated in epileptogenic brain regions in humans and is clearly involved in animal models of epilepsy. Inflammatory mediators in the blood and m...

Treatment of Gait Disorders in Children With Dravet Syndrome
https://clinicaltrials.gov/ct2/show/NCT03857451

Apr 14th, 2022 - The problem under investigation is the reduced functional mobility of patients with Dravet syndrome resulting from a crouch gait pattern. The solution, proposed in this research project, is the development of a decision framework based upon clinic...

Impact of Pediatric Medical Emergencies' in Situ Simulations
https://clinicaltrials.gov/ct2/show/NCT05247580

Mar 8th, 2022 - The SUrVIS project is structured around a 12-persons one-day interdisciplinary in situ simulation training sessions including: Training in... Recognition of the critically ill child and pediatric cardiopulmonary arrest The call for help according ...

Status Epilepticus Unicenter Population (STEP UP) Study
https://clinicaltrials.gov/ct2/show/NCT04204863

Mar 4th, 2022 - The aim of this observational single-center cohort study is to gain a deeper understanding regarding the effects of treatment adaption based on information from outcome prediction models, risk stratification, as well as treatment monitoring, detec...

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News  172 results

New Score May Help Predict Outcome for Some Cases of Status Epilepticus
https://www.medscape.com/viewarticle/972621

Apr 25th, 2022 - NEW YORK (Reuters Health) - In patients with status epilepticus that is "less damaging" to the brain, a three-factor scoring system may help predict post-discharge outcomes, researchers suggest. As reported in JAMA Neurology, Dr. Christoph Beier o...

World Answers Ukrainian Neurologists' Desperate Cry for Help
https://www.medscape.com/viewarticle/970099

Mar 10th, 2022 - As neurologists in war-torn Ukraine plead for assistance, professional societies around the world are taking action. "There are children in dire need of their antiseizure medications (ASMs) going into status epilepticus," tweeted pediatric neurolo...

A Rare Case of Status Epilepticus in a Patient Prescribed CBD
https://www.medscape.com/viewarticle/966903

Feb 2nd, 2022 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner reporting on the recent, virtually held American Epilepsy Society meeting. With me today is Dr Charles Szabo, professor and chief of epile...

'Very High' Risk of Epilepsy 1 Year After Stroke
https://www.medscape.com/viewarticle/964662

Dec 13th, 2021 - Patients who experience stroke have a "very high" risk of epilepsy 1 year later, new research shows. Results from a large registry study reveals patients who experienced a severe intracerebral hemorrhage (ICH) had an almost 10% chance of developin...

Paramedic Treatment of Status Epilepticus Rarely Consistent With Guidelines
https://www.medpagetoday.com/neurology/seizures/95730

Nov 17th, 2021 - Prehospital treatment of people with status epilepticus rarely was consistent with expert guidelines, an analysis of emergency medical service (EMS) agency records showed. Initial treatment was concordant with guidelines in only 3.9% of 9,176 EMS ...

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Patient Education  2 results see all →