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ALLMedicine™ Acanthamoeba Keratitis Center

Research & Reviews  184 results

Acanthamoeba scleral abscess reoccurring after penetrating keratoplasty.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220518
BMJ Case Reports; Barnett B, McCloskey K

Jun 23rd, 2021 - Two months following penetrating keratoplasty for Acanthamoeba keratitis, a 76-year-old man was referred due to inability to wean high-dose topical steroids. Despite a very healthy graft and minimal pain, a scleral abscess involving three clock ho...

Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodolo...
https://doi.org/10.1080/14787210.2021.1924673
Expert Review of Anti-infective Therapy; Shing B, Balen M et. al.

May 1st, 2021 - Introduction: Acanthamoeba encompasses several species of free-living ameba encountered commonly throughout the environment. Unfortunately, these species of ameba can cause opportunistic infections that result in Acanthamoeba keratitis, granulomat...

In vitro amoebicidal effects of arabinogalactan-based ophthalmic solution.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099451
International Journal for Parasitology. Drugs and Drug Re... Reyes-Batlle M, Rodríguez-Talavera I et. al.

Apr 26th, 2021 - The main corneal infections reported worldwide are caused by bacteria and viruses but, recently, the number of Acanthamoeba keratitis (AK) cases has increased. Acanthamoeba genus is an opportunistic free living protozoa widely distributed in envir...

Chorismate mutase peptide antibody enables specific detection of Acanthamoeba.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064552
PloS One; Lee HA, Chu KB et. al.

Apr 24th, 2021 - Accurate and rapid diagnosis of Acanthamoeba keratitis (AK) is difficult. Although the diagnostic procedure for AK has improved, further development and effective diagnostic tool utilization for AK need to continue. Chorismate mutase is a key regu...

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Clinicaltrials.gov  2 results

Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Subjects Affected by Acanthamoeba Keratitis
https://clinicaltrials.gov/ct2/show/NCT03274895

Aug 28th, 2018 - This is a randomized, assessor-masked, active-controlled, multiple center, parallel-group Phase 3 study to evaluate the efficacy, safety and tolerability of 0.08% PHMB ophthalmic solution compared to the conventional 0.02% PHMB + 0.1% propamidine ...

Parasitic Ulcer Treatment Trial Pilot
https://clinicaltrials.gov/ct2/show/NCT03484507

Aug 2nd, 2018 - Acanthamoeba keratitis is a rare eye infection that is difficult to treat. The mainstay of therapy is a biguanide agent such as chlorhexidine, though recent studies have found povidone iodine to be effective for killing acanthamoeba organisms in v...

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News  10 results

Preventable Eye Infection Cases Rise for Contact Lens Users
https://www.medscape.com/viewarticle/902984

Oct 4th, 2018 - Researchers have warned of a new outbreak of a rare but preventable eye infection affecting people in the UK who wear contact lenses. Acanthamoeba keratitis causes corneal inflammation and pain.   For people who get this condition, it is hugely de...

Preventable Eye Infection Cases Rise for Contact Lens Users
https://www.staging.medscape.com/viewarticle/902984

Oct 4th, 2018 - Researchers have warned of a new outbreak of a rare but preventable eye infection affecting people in the UK who wear contact lenses. Acanthamoeba keratitis causes corneal inflammation and pain.  Around a quarter of patients infected may lose most...

Water woes: Recognizing and treating recreational water illness
https://www.mdedge.com/familymedicine/article/101370/infectious-diseases/water-woes-recognizing-and-treating-recreational/page/0/1
Pediatric News;

Jul 21st, 2015 - Acanthamoeba keratitis is a potentially blinding infection of the cornea that primarily occurs in individuals who wear contact lenses. Risk factors for the infection include swimming, showering, and use of hot tubs while wearing contact lenses.

FDA Panel Debates New Guidance for Proper Use of Contacts
https://www.medscape.com/viewarticle/825133

May 14th, 2014 - When revising guidelines for manufacturers of contact lenses and lens care products, US Food and Drug Administration (FDA) staff members should not require the industry to be responsible for patient noncompliance with using products as directed. T...

Shedding New Light on a Potentially Blinding Eye Infection
https://www.medscape.com/viewarticle/769679

Aug 27th, 2012 - Hello. I'm Dr. Allison Brown, an epidemiologist with the Waterborne Disease Prevention Branch at the Centers for Disease Control and Prevention (CDC). I am here today as part of the CDC Expert Commentary Series on Medscape. I would like to speak w...

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Patient Education  1 results see all →