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Research & Reviews  2,520,569 results

Diffuse Bone Marrow Involvement of Multiple Myeloma on 18FPSMA-1007 PET/CT: Is There a ...
https://doi.org/10.1097/RLU.0000000000004286
Clinical Nuclear Medicine; Michalski K, Jilg CA et. al.

May 28th, 2022 - A 71-year-old man presented with chronic anemia (hemoglobin 7.3 g/dL). Further serum analyses showed elevated prostate-specific antigen (13 ng/mL), suggestive of prostate cancer. However, ultrasound-guided transrectal sextant biopsy did not find a...

Renal Pelvis Immunoglobulin G4-Related Disease Mimicking Malignant Tumor: A Case of 18F...
https://doi.org/10.1097/RLU.0000000000004292
Clinical Nuclear Medicine; Zhang Z, Liu Y et. al.

May 28th, 2022 - A space-occupying lesion in the left renal pelvis was found in a 56-year-old man. The patient voluntarily participated in a clinical trial of 68Ga-FAPI in solid tumors. PET/CT images revealed an intense 18F-FDG and 68Ga-FAPI uptake in this lesion....

Hypermetabolic Esophagitis Dessicans Superficialis Mimicking Esophageal Cancer on FDG P...
https://doi.org/10.1097/RLU.0000000000004303
Clinical Nuclear Medicine; Mamaliga T, Liu Y

May 28th, 2022 - An 83-year-old man with history of multiple myeloma obtained an FDG PET/CT for surveillance. Although there was no evidence of metabolically active myeloma, an incidental highly FDG-avid focus was noted at the gastroesophageal junction. Findings w...

Reverse Liver Spleen Uptake on 68GaGa-PSMA-11 PET/CT.
https://doi.org/10.1097/RLU.0000000000004285
Clinical Nuclear Medicine; Abubakar S, Al Riyami K et. al.

May 28th, 2022 - An 80-year-old man underwent [68Ga]Ga-PSMA-11 PET/CT for staging of high-risk prostate cancer. Homogeneously increased liver uptake, more than 3-fold the splenic uptake, was seen. There was no hepatic lesion evident on CT. A higher liver to spleni...

Solitary Fibrous Tumor of the Bone Detected by FDG PET/CT.
https://doi.org/10.1097/RLU.0000000000004290
Clinical Nuclear Medicine; Li J, Kuang A et. al.

May 28th, 2022 - Solitary fibrous tumor as a rare mesenchymal tumor can occur in a wide variety of body sites, including serosal membranes, liver, lung, and deep soft tissues; however, primary tumor arising in bone is rarely documented. Herein, we reported the MRI...

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Guidelines  5,112 results

Current Role of Immunotherapy in Gastric, Esophageal and Gastro-Esophageal Junction Can...
https://doi.org/10.3390/curroncol29050257
Current Oncology (Toronto, Ont.); Mulder K, Lim H et. al.

May 28th, 2022 - Gastric, esophageal and gastro-esophageal junction cancers are associated with inferior outcomes. For early-stage disease, perioperative chemotherapy or chemoradiation followed by surgery is the standard treatment. For most patients with advanced ...

CDC: Up to Five Monkeypox Cases Now Presumed in the U.S.
https://www.medpagetoday.com/infectiousdisease/publichealth/98884
MedPage Today; Walker M.

May 24th, 2022 - With one confirmed case and four presumptive cases of monkeypox in the U.S., clinicians should continue to be on high alert if their patients report new onset of rash, especially in the genital or perianal area, CDC staff said Monday. The one c...

ACOG Practice Bulletin No. 147: Lynch Syndrome: Correction.
https://doi.org/10.1097/AOG.0000000000004736 10.1097/01.AOG.0000456325.50739.72
Obstetrics and Gynecology;

May 21st, 2022 - ACOG Practice Bulletin No. 147: Lynch Syndrome: Correction.|2022||diagnosis,therapy,

ACR-ABS-ASTRO Practice Parameter for Transperineal Permanent Brachytherapy of Prostate ...
https://doi.org/10.1097/COC.0000000000000915
American Journal of Clinical Oncology; Bittner NHJ, Cox BW et. al.

May 20th, 2022 - The American College of Radiology (ACR), American Brachytherapy Society (ABS), and American Society for Radiation Oncology (ASTRO) have jointly developed the following practice parameter for transperineal permanent brachytherapy of prostate cancer...

Here's What Happened to Asthma, COPD Admissions After a Big Polluter Shut Down
https://www.medpagetoday.com/meetingcoverage/ats/98781
MedPage Today; Gever J.

May 18th, 2022 - SAN FRANCISCO -- For neighborhoods near a major coking operation in Pittsburgh, its shutdown at the end of 2015 was followed by markedly lower rates of respiratory disease hospitalizations, researchers reported here. Inpatient admissions for ch...

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Drugs  69,571 results see all →

Clinicaltrials.gov  100,850 results

Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT04756713

May 27th, 2022 - This is a randomized, multicenter clinical trial including patients seen at one of 13 gestational trophoblastic disease reference centers in Brazil. Subjects are eligible if they have low-risk gestational trophoblastic neoplasia according to FIGO ...

Developing Brain, Impulsivity and Compulsivity
https://clinicaltrials.gov/ct2/show/NCT04631042

May 27th, 2022 - Study Description: Many neuropsychiatric disorders have extreme impairing impulsivity and compulsivity behaviors at their core. We hypothesized that the development of symptoms of impulsivity and compulsivity during childhood/adolescence and early...

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach
https://clinicaltrials.gov/ct2/show/NCT04685200

May 27th, 2022 - In this single-site, small-scale prospective natural history study, we intend to recruit up to 40 patients with PSC diagnosed by standard clinical, biochemical, or imaging features (including up to 30 with a known diagnosis of IBD) and up to 90 co...

Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)
https://clinicaltrials.gov/ct2/show/NCT04740307

May 27th, 2022 - The purpose of this study is to evaluate the safety and efficacy of fixed dose coformulated pembrolizumab/quavonlimab (MK-1308A) plus lenvatinib in a first line (1L) hepatocellular carcinoma (HCC) setting. No hypothesis testing will be performed.

Monocyte Antigen Carrier Cells for Newly Diagnosed GBM
https://clinicaltrials.gov/ct2/show/NCT04741984

May 27th, 2022 - The investigational vaccine (MT-201-GBM) in this study is made from a type of immune cell called monocytes, which have been engineered to express a cytomegalovirus (CMV) protein. The monocyte vaccines are made from the patient's own cells, which a...

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News  186,350 results

Medical trauma an under-recognized trigger for PTSD
https://www.mdedge.com/psychiatry/article/255051/ptsd/medical-trauma-under-recognized-trigger-ptsd
Randy Dotinga

May 27th, 2022 - NEW ORLEANS – Recent studies have confirmed that posttraumatic stress disorder can be triggered by health-related stress such as stints in the ICU and life-threatening medical emergencies, but most psychiatrists may not be aware of the latest rese.

Urinating multiple times per night
https://www.mdedge.com/prostate-cancer-challenge-center/article/255032/prostate-cancer/urinating-multiple-times-night

May 27th, 2022 - On the basis of the patient's history and presentation, this is likely a case of adenocarcinoma of the prostate. Although most patients with prostate cancer are diagnosed on screening, when localized symptoms do occur, they may include urinary fre.

Sugar-sweetened beverage and sugar consumption tied with incidence of and mortality from proximal colon cancer
https://www.mdedge.com/hematology-oncology/article/255022/gastrointestinal-cancer/sugar-sweetened-beverage-and-sugar

May 27th, 2022 - Key clinical point: High sugar-sweetened beverage (SSB) and total fructose intake was associated with increased incidence of and mortality from proximal colon cancer, especially during the later stages of colorectal tumorigenesis. Major finding: S.

ctDNA: Strong prognostic biomarker but lacks true clinical utility in mCRC
https://www.mdedge.com/hematology-oncology/article/255021/gastrointestinal-cancer/ctdna-strong-prognostic-biomarker-lacks

May 27th, 2022 - Key clinical point: Circulating tumor DNA (ctDNA) has substantiated its role as a strong prognostic biomarker in patients with metastatic colorectal cancer (mCRC). However, uncovering its true clinical value for these patients calls for prospectiv.

Rapid Review Quiz: Nonalcoholic Fatty Liver Disease (NAFLD)
https://reference.medscape.com/viewarticle/973952

May 27th, 2022 - Approximately 25% of the global population has nonalcoholic fatty liver disease (NAFLD), a broad term that covers a range of conditions. NAFLD is defined by the presence of macrovesicular steatosis without secondary causes, such as chronic use of ...

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Patient Education  4,906 results see all →