×
About 117 results

ALLMedicine™ Acute Myelomonocytic Leukemia Center

Research & Reviews  57 results

Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal...
https://doi.org/10.21873/anticanres.14488
Anticancer Research; Thadi A, Lewis L et. al.

Sep 3rd, 2020 - Anticancer peptide PNC-27 binds to HDM-2 protein on cancer cell membranes inducing the formation of cytotoxic transmembrane pores. Herein, we investigated HDM-2 membrane expression and the effect of PNC-27 treatment on human non-stem cell acute my...

LILRB4-targeting Antibody-Drug Conjugates for the Treatment of Acute Myeloid Leukemia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921214
Molecular Cancer Therapeutics; Anami Y, Deng M et. al.

Sep 3rd, 2020 - Acute myeloid leukemia (AML) is the most common and aggressive blood cancer in adults. In particular, significant unmet medical needs exist for effective treatment strategies for acute myelomonocytic leukemia (M4) and acute monocytic leukemia (M5)...

Penile Ulcer due to Leukemia Cutis-A Rare Diagnosis Not to Be Missed.
https://doi.org/10.1097/DAD.0000000000001604
The American Journal of Dermatopathology; Toh JJH, Chia HY et. al.

Jan 8th, 2020 - We present a rare case of leukemia cutis presenting with an ulcer on the ventral penis. A 60-year-old Chinese man was referred for a penile ulcer of 10 days. He was diagnosed with acute myelomonocytic leukemia 6 months earlier and had received 2 c...

Acute myelomonocytic leukemia
https://rarediseases.info.nih.gov/diseases/529/acute-myelomonocytic-leukemia

Jul 31st, 2019 - The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 517 Definition A rare acute myeloid leukemia disorder characterized by increased blast cells (myeloblasts, monobla...

A Case of Granulocytic Sarcoma or Extramedullary Acute Myelomonocytic Leukemia of the G...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213823
The American Journal of Case Reports; Holzwanger EA, Alam Z et. al.

Oct 25th, 2018 - BACKGROUND Granulocytic sarcoma, or 'chloroma,' due to extramedullary acute myeloid leukemia (AML) or due to acute myelomonocytic leukemia (AML M5), is rare and is associated with a poor prognosis. This report is of a case of granulocytic sarcoma ...

see more →

Guidelines  1 results

Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme
https://www.nature.com/articles/1704525
Bone Marrow Transplantation;

May 23rd, 2004 - The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation (HSCT) is to predict negative events, such as disease relapse, graft rejection and graft-versus-host disease, in order to intervene with appropriate therap...

see more →

Clinicaltrials.gov  57 results

Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal...
https://doi.org/10.21873/anticanres.14488
Anticancer Research; Thadi A, Lewis L et. al.

Sep 3rd, 2020 - Anticancer peptide PNC-27 binds to HDM-2 protein on cancer cell membranes inducing the formation of cytotoxic transmembrane pores. Herein, we investigated HDM-2 membrane expression and the effect of PNC-27 treatment on human non-stem cell acute my...

LILRB4-targeting Antibody-Drug Conjugates for the Treatment of Acute Myeloid Leukemia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921214
Molecular Cancer Therapeutics; Anami Y, Deng M et. al.

Sep 3rd, 2020 - Acute myeloid leukemia (AML) is the most common and aggressive blood cancer in adults. In particular, significant unmet medical needs exist for effective treatment strategies for acute myelomonocytic leukemia (M4) and acute monocytic leukemia (M5)...

Penile Ulcer due to Leukemia Cutis-A Rare Diagnosis Not to Be Missed.
https://doi.org/10.1097/DAD.0000000000001604
The American Journal of Dermatopathology; Toh JJH, Chia HY et. al.

Jan 8th, 2020 - We present a rare case of leukemia cutis presenting with an ulcer on the ventral penis. A 60-year-old Chinese man was referred for a penile ulcer of 10 days. He was diagnosed with acute myelomonocytic leukemia 6 months earlier and had received 2 c...

Acute myelomonocytic leukemia
https://rarediseases.info.nih.gov/diseases/529/acute-myelomonocytic-leukemia

Jul 31st, 2019 - The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 517 Definition A rare acute myeloid leukemia disorder characterized by increased blast cells (myeloblasts, monobla...

A Case of Granulocytic Sarcoma or Extramedullary Acute Myelomonocytic Leukemia of the G...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213823
The American Journal of Case Reports; Holzwanger EA, Alam Z et. al.

Oct 25th, 2018 - BACKGROUND Granulocytic sarcoma, or 'chloroma,' due to extramedullary acute myeloid leukemia (AML) or due to acute myelomonocytic leukemia (AML M5), is rare and is associated with a poor prognosis. This report is of a case of granulocytic sarcoma ...

see more →

News  2 results

Outcomes worse with secondary and therapy-related AML compared with de novo AML
https://www.mdedge.com/hematology-oncology/article/102154/aml/outcomes-worse-secondary-and-therapy-related-aml-compared-de
Jennifer Kelly Shepphird

Aug 24th, 2015 - Clinical outcomes were significantly worse among younger patients with secondary and therapy-related acute myeloid leukemia (sAML and tAML, respectively) compared with de novo disease, suggesting the presence of distinct AML subtypes, in a study p.

Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme
https://www.nature.com/articles/1704525
Bone Marrow Transplantation;

May 23rd, 2004 - The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation (HSCT) is to predict negative events, such as disease relapse, graft rejection and graft-versus-host disease, in order to intervene with appropriate therap...

see more →