About 1,810 results

ALLMedicine™ Adenoid Cystic Carcinoma Center

Research & Reviews  699 results

Treatment response to eribulin and anlotinib in lung metastases from rare perianal aden...
Anti-cancer Drugs; Zheng S, Li H et. al.

Jul 30th, 2021 - Adenoid cystic carcinoma (ACC) is a rare salivary glands tumor and often displays aggressive behavior with frequent relapse and metastasis. The terminal ACC lacks standard treatment guidelines and is always accompanied by poor prognosis. Here, we ...

Randomized phase II study of axitinib versus observation in patients with recurred or m...
Clinical Cancer Research : an Official Journal of the Ame... Kang EJ, Ahn MJ et. al.

Jul 29th, 2021 - The role of chemotherapy in adenoid cystic carcinoma (ACC) is controversial because ACC is usually stable without chemotherapy and lack of randomized trials. Here, we conducted the first randomized trial to evaluate the efficacy of axitinib as com...

Rare Brain Metastasis in Parotid Adenoid Cystic Carcinoma Detected on 68Ga-PSMA PET/CT.
Clinical Nuclear Medicine; Datta Gupta S, Arora G et. al.

Jul 29th, 2021 - We present the case of a 45-year-old woman with known adenoid cystic carcinoma of the right parotid gland, postexcision and postoperative radiation therapy. She was followed up on 18F-FDG PET/CT, which revealed minimal local residual disease and b...

Adenoid cystic Carcinoma and Carbon ion Only irradiation (ACCO): Study protocol for a p...
BMC Cancer; Lang K, Adeberg S et. al.

Jul 17th, 2021 - Adenoid cystic carcinoma is a rare form of head and neck cancer with a slow, but aggressive growth pattern which remains a challenge for local tumor control. Based on phase II data, radiation treatment using partially high LET radiation results in...

Proteasome inhibitors suppress MYB oncogenic activity in a p300-dependent manner.
Cancer Letters; Yusenko MV, Biyanee A et. al.

Jul 14th, 2021 - Studies of the role of MYB in human malignancies have highlighted MYB as a potential drug target for acute myeloid leukemia (AML) and adenoid cystic carcinoma (ACC). Although transcription factors are often considered un-druggable, recent work has...

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Clinicaltrials.gov  17 results

Study of E7389 Liposomal Formulation in Subjects With Solid Tumor

Apr 28th, 2020 - The maximum tolerated dose (MTD) of E7389 liposomal formulation (E7389-LF) will be determined in the dose escalation part. Safety, pharmacokinetics (PK) and efficacy will be assessed using treatment regimen evaluated in dose escalation part in par...

Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC

Apr 17th, 2020 - This study evaluates intratumoral administration of CV8102 in patients with advanced melanoma, squamous cell carcinoma of the skin, squamous cell carcinoma of the head and neck, or adenoid cystic carcinoma. Patients will receive CV8102 as single a...

A Study Of AL101 In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations

Apr 7th, 2020 - This is a Phase 2, non comparative, open label, multicenter study of AL101 in patients with recurrent or metastatic ACC who harbor NOTCH 1,2,3,4 activating mutations.

A Study of Apatinib in Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck

Sep 26th, 2018 - This is a non-randomized, phase II, open label study of Apatinib Mesylate in patients with Head and neck recurrent/metastatic adenoid cystic carcinoma (ACC). The primary purpose of this study is to evaluate the efficacy and safety of Apatinib Mesy...

Chidamide Combined With Cisplatin in Head and Neck Adenoid Cystic Carcinoma (HNACC)

Aug 22nd, 2018 - Adenoid cystic carcinomas (ACCs) constitute of 1% of head and neck cancers. This type of tumor grows slowly with a high potential of local recurrence. Approximately 50% of patients develop distant metastases, and 33% patients die within 2 years. T...

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News  6 results

Time for 'Heavy Ion' Therapy to Come Home to the US?

Feb 6th, 2017 - Heavy ion therapy — the most potent form of radiotherapy — may finally become available in the United States. The irony is that it was first investigated in the United States, but decades later, it has still not reached the clinic. In contrast, it...

An Unusual Cause of Shortness of Breath: Primary Tracheal Basal Cell Adenocarcinoma

Aug 26th, 2016 - The abundant minor salivary gland tissue in the upper respiratory tract can potentially develop neoplasia the same as the wide spectrum seen in head and neck salivary gland tumors. The most recent (2004) WHO Pathology and Genetics of Tumours of th.

Trichoepithelioma and Spiradenoma Collision Tumor

Apr 8th, 2015 - Cylindromas are composed of basaloid islands interconnected in a jigsaw puzzle configuration (Figure 5B). 4 Similar to spiradenomas, they also are composed of 2 cell populations.

Early Cutaneous Metastasis of Adenoid Cystic Carcinoma of the Salivary Gland

Jun 11th, 2014 - Conclusion Cutaneous metastasis represents an important sign of disease progression, allowing for the early discovery of systemic diffusion of the tumor as well as adjustment of the therapeutic approach. Our patient not only highlights a rare case.

AACR-NCI-EORTC: Early Nerve-Sparing Benefits Seen with Oncolytic Virus

Oct 26th, 2007 - Action Points Caution patients that the study was done in mice and further research is needed before the agent can be used clinically. SAN FRANCISCO, Oct. 26 -- A modified herpes virus may target cancer cells invading the nervous system while pres...

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Patient Education  2 results see all →