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About 2,198 results

ALLMedicine™ Anaplastic Large Cell Lymphoma Center

Research & Reviews  757 results

Remission of refractory granulomatous primary cutaneous anaplastic large cell lymphoma ...
https://doi.org/10.1136/bcr-2021-242896
BMJ Case Reports; Sasapu A, Dunn ALJ et. al.

Jul 22nd, 2021 - Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is a rare non-Hodgkin's lymphoma that arises as a single, or multiple dome-shaped tumours on the skin. The histology is characterised by the presence of atypical lymphocytes with large irr...

Considerations on the Demography of BIA-ALCL in European Countries Based on an E(A)SAPS...
https://doi.org/10.1007/s00266-021-02411-3 10.1007/s00266-012-0015-y 10.1182/blood-2016-01-643569 10.1093/asj/sjz021 10.1093/asj/sjz136.PMID:31242279;PMCID:PMC7006872.Aug;136(2):426.PMID:25490535 10.1097/GOX.0000000000002348
Aesthetic Plastic Surgery; Stark B, Magnéli M et. al.

Jul 21st, 2021 - A growing body of evidence indicates that breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is associated with the use of certain breast implants. Regional variations have been reported, and a genetic susceptibility has also been...

Identification and Characterization of Cancer Stem-Like Cells in ALK-Positive Anaplasti...
https://doi.org/10.3390/cimb43020041
Current Issues in Molecular Biology; Li J, Haque M et. al.

Jul 21st, 2021 - Transcription factors Sox2 and Oct4 are essential in maintaining the pluripotency of embryonic stem cells and conferring stemness in cancer stem-like (CSL) cells. SORE6, an in-vitro reporter system, was designed to quantify the transcription activ...

Phase II single-arm study of brentuximab vedotin in Chinese patients with relapsed/refr...
https://doi.org/10.1080/17474086.2021.1942831
Expert Review of Hematology; Song Y, Guo Y et. al.

Jul 19th, 2021 - Relapsed/refractory (R/R) classical HL (cHL) and systemic anaplastic large-cell lymphoma (sALCL) treatment options are limited in China and there is a need for new therapies. This single-arm, open-label, multicenter, Phase II study assessed effica...

Breast Implant-associated Anaplastic Large Cell Lymphoma Diagnosis 6 Years after Implan...
https://doi.org/10.1097/SAP.0000000000002945
Annals of Plastic Surgery; Barnea Y, Clemens MW et. al.

Jul 16th, 2021 - We present a case report of a 48-year-old woman with a late-onset seroma of her left breast, 6 years after removal of her textured breast implants. At that time, she also had a late-onset seroma of her left breast, and capsulectomy was performed a...

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Guidelines  4 results

UK Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic La...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894347
British Journal of Haematology; Turton P, El-Sharkawi D et. al.

Nov 22nd, 2020 - Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T-cell non-Hodgkin Lymphoma (NHL) associated with breast implants. Raising awareness of the possibility of BIA-ALCL in anyone with breast implants and new breast sy...

Best Practices Guideline for the Pathologic Diagnosis of Breast Implant-Associated Anap...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106983
Journal of Clinical Oncology : Official Journal of the Am... Jaffe ES, Ashar BS et. al.

Feb 11th, 2020 - To provide guidelines for the accurate pathologic diagnosis of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), the preoperative evaluation of the patient with suspected BIA-ALCL, and the pathologic evaluation of the capsulecto...

NCCN Consensus Guidelines for the Diagnosis and Management of Breast Implant-Associated...
https://doi.org/10.1093/asj/sjw259
Aesthetic Surgery Journal; Clemens MW, Horwitz SM

Feb 11th, 2017 - Published case series demonstrate a lack of treatment standardization for breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) with a wide variety of therapeutic strategies being employed at all stages of disease. The National Compr...

Guidelines for the management of mature T-cell and NK-cell neoplasms (excluding cutaneo...
https://doi.org/10.1111/j.1365-2141.2011.08651.x
British Journal of Haematology; Dearden CE, Johnson R et. al.

Apr 12th, 2011 - The peripheral T-cell neoplasms are a biologically and clinically heterogeneous group of rare disorders that result from clonal proliferation of mature post-thymic lymphocytes. Natural killer (NK) cell neoplasms are included in this group. The Wor...

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Drugs  2 results see all →

Clinicaltrials.gov  40 results

Investigation of Tipifarnib in Treatment of Subjects With PTCL That Have Not Responded to Standard Therapy.
https://clinicaltrials.gov/ct2/show/NCT02464228

Mar 3rd, 2020 - This Phase II study will investigate the antitumor activity in terms of ORR of tipifarnib in subjects with relapsed or refractory PTCL. The first 18 subjects may be of the following PTCL sub-types: PTCL not otherwise specified (PTCL-NOS), angioimm...

Brigatinib in Relapsed or Refractory ALK-Positive Anaplastic Large Cell Lymphoma
https://clinicaltrials.gov/ct2/show/NCT03719898

Feb 27th, 2020 - Although patients with ALK+ anaplastic large cell lymphoma (ALCL), a type of peripheral T-cell lymphoma (PTCL), are considered to have a favorable prognosis, relapse is not uncommon if multiple International Prognostic Index (IPI) risk factors, ag...

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma
https://clinicaltrials.gov/ct2/show/NCT03719105

Feb 27th, 2020 - Patients are in 2 cohorts: Cohort 1: dexamethasone, methotrexate, ifosfamide, pegaspargase, and etoposide (modified SMILE) chemotherapy regimen alone and pembrolizumab in children, adolescents, and young adults with advanced stage NK lymphoma and ...

Testing AT13387 (Onalespib) in Patients With Relapsed/Refractory ALK+ Anaplastic Large Cell Lymphoma (ALCL), Mantle Cell Lymphoma (MCL), and BCL6+ Diffuse Large B Cell Lymphoma (DLBCL)
https://clinicaltrials.gov/ct2/show/NCT02572453

Jan 13th, 2020 - PRIMARY OBJECTIVE: I. Overall response rate (ORR) to single agent AT13387 (onalespib) as measured by the proportion of partial and complete responses (PR + CR) in patients with relapsed/refractory ALK positive (+) anaplastic large cell lymphoma (A...

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News  76 results

Textured Implants Linked to Increased Breast Cancer Recurrence Risk
https://www.medscape.com/viewarticle/939069

Oct 13th, 2020 - NEW YORK (Reuters Health) - Using textured implants for reconstruction after mastectomy is associated with greater risk of breast cancer recurrence compared to smooth implants, according to new findings in JAMA Surgery. "We initiated this study fo...

NICE: Brentuximab Vedotin for Untreated sALCL
https://www.medscape.com/viewarticle/933703

Jul 9th, 2020 - The National Institute for Health and Care Excellence (NICE) has published final draft guidance recommending brentuximab vedotin (Adcetris, Takeda) with cyclophosphamide, doxorubicin, and prednisone (CHP) for untreated systemic anaplastic large ce...

NICE: Brentuximab Vedotin for Untreated sALCL
https://www.staging.medscape.com/viewarticle/933703

Jul 9th, 2020 - The National Institute for Health and Care Excellence (NICE) has published final draft guidance recommending brentuximab vedotin (Adcetris, Takeda) with cyclophosphamide, doxorubicin, and prednisone (CHP) for untreated systemic anaplastic large ce...

Number of Cases of Breast Implant-linked Lymphoma in the UK
https://www.medscape.com/viewarticle/933637

Jul 8th, 2020 - As of April 2020, there have been 68 cases of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) reported in the UK. This figure includes cases where the original implantation did not occur in the UK. Based on the number of cases,...

Asymptomatic, erythematous papules on the neck
https://www.mdedge.com/dermatology/article/217287/medical-dermatology/make-diagnosis-march-2020?channel=39212
Donna Bilu Martin, MD

Feb 13th, 2020 - The patient’s biopsy showed sparse and grouped and slightly enlarged atypical stained mononuclear cells in mostly perifollicular areas with focal epidermotropism. CD30 staining was positive.

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