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About 1,685 results

ALLMedicine™ Anaplastic Thyroid Cancer Center

Research & Reviews  805 results

Multimodal Treatments and Outcomes for Anaplastic Thyroid Cancer Before and After Tyros...
https://doi.org/10.1530/EJE-20-1482
European Journal of Endocrinology; Park J, Jung HA et. al.

Apr 14th, 2021 - Anaplastic thyroid cancer (ATC) has dismal prognosis, and there is no effective treatment. We aimed to evaluate the efficacy of tyrosine kinase inhibitor (TKI) therapy in real world clinic, and to suggest the most effective treatment modality acco...

Cell competition between anaplastic thyroid cancer and normal thyroid follicular cells ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016217
PloS One; Amrenova A, Suzuki K et. al.

Apr 1st, 2021 - The microenvironment of an early-stage tumor, in which a small number of cancer cells is surrounded by a normal counterpart milieu, plays a crucial role in determining the fate of initiated cells. Here, we examined cell competition between anaplas...

Efficacy of adavosertib therapy against anaplastic thyroid cancer.
https://doi.org/10.1530/ERC-21-0001
Endocrine-related Cancer; Lu YL, Huang YT et. al.

Mar 26th, 2021 - Wee1 is a kinase that regulates the G2/M progression by inhibition of CDK1, which is critical for ensuring DNA damage repair before initiation of mitotic entry. Targeting Wee1 may be a potential strategy in the treatment of anaplastic thyroid canc...

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic...
https://doi.org/10.1089/thy.2020.0944
Thyroid : Official Journal of the American Thyroid Associ... Bible KC, Kebebew E et. al.

Mar 17th, 2021 - Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Since the guidelines for the management of ATC by the American Thyroid Association were first published in 2012, significant clinical and scientific ad...

Inhibitor of apoptosis protein Livin promotes tumor progression and chemoradioresistanc...
https://doi.org/10.3892/or.2021.7969
Oncology Reports; Kim HK, Kim SA et. al.

Mar 2nd, 2021 - Anaplastic thyroid cancer (ATC) is characterized by a rapid and aggressive course of progression. Despite significant advances in surgery, radiotherapy and chemotherapy, the disease‑specific mortality due to ATC is approximately 100%. New strategi...

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Guidelines  2 results

American Thyroid Association guidelines for management of patients with anaplastic thyr...
https://doi.org/10.1089/thy.2012.0302
Thyroid : Official Journal of the American Thyroid Associ... Smallridge RC, Ain KB et. al.

Nov 7th, 2012 - Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum patient management and require a multidisciplinary team approach. Here we present ...

American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid C...
https://www.liebertpub.com/doi/10.1089/thy.2012.0302
Robert C. Smallridge

Nov 5th, 2012 - These are the first comprehensive guidelines for ATC and provide recommendations for management of this extremely aggressive malignancy. Patients with stage IVA/IVB resectable disease have the best prognosis, particularly if a multimodal approach.

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Clinicaltrials.gov  847 results

Multimodal Treatments and Outcomes for Anaplastic Thyroid Cancer Before and After Tyros...
https://doi.org/10.1530/EJE-20-1482
European Journal of Endocrinology; Park J, Jung HA et. al.

Apr 14th, 2021 - Anaplastic thyroid cancer (ATC) has dismal prognosis, and there is no effective treatment. We aimed to evaluate the efficacy of tyrosine kinase inhibitor (TKI) therapy in real world clinic, and to suggest the most effective treatment modality acco...

Cell competition between anaplastic thyroid cancer and normal thyroid follicular cells ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016217
PloS One; Amrenova A, Suzuki K et. al.

Apr 1st, 2021 - The microenvironment of an early-stage tumor, in which a small number of cancer cells is surrounded by a normal counterpart milieu, plays a crucial role in determining the fate of initiated cells. Here, we examined cell competition between anaplas...

Efficacy of adavosertib therapy against anaplastic thyroid cancer.
https://doi.org/10.1530/ERC-21-0001
Endocrine-related Cancer; Lu YL, Huang YT et. al.

Mar 26th, 2021 - Wee1 is a kinase that regulates the G2/M progression by inhibition of CDK1, which is critical for ensuring DNA damage repair before initiation of mitotic entry. Targeting Wee1 may be a potential strategy in the treatment of anaplastic thyroid canc...

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic...
https://doi.org/10.1089/thy.2020.0944
Thyroid : Official Journal of the American Thyroid Associ... Bible KC, Kebebew E et. al.

Mar 17th, 2021 - Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Since the guidelines for the management of ATC by the American Thyroid Association were first published in 2012, significant clinical and scientific ad...

Inhibitor of apoptosis protein Livin promotes tumor progression and chemoradioresistanc...
https://doi.org/10.3892/or.2021.7969
Oncology Reports; Kim HK, Kim SA et. al.

Mar 2nd, 2021 - Anaplastic thyroid cancer (ATC) is characterized by a rapid and aggressive course of progression. Despite significant advances in surgery, radiotherapy and chemotherapy, the disease‑specific mortality due to ATC is approximately 100%. New strategi...

see more →

News  31 results

Targeted Treatment Tied to Longer Survival in Patients With Anaplastic Thyroid Cancer
https://www.medscape.com/viewarticle/936044

Aug 20th, 2020 - NEW YORK (Reuters Health) - With the introduction of targeted treatments for anaplastic thyroid carcinoma, patients have seen significant improvements in survival, according to a new report. "Over the last 5 years, a greater understanding of the m...

Targeted Treatment Tied to Longer Survival in Patients With Anaplastic Thyroid Cancer
https://www.staging.medscape.com/viewarticle/936044

Aug 20th, 2020 - NEW YORK (Reuters Health) - With the introduction of targeted treatments for anaplastic thyroid carcinoma, patients have seen significant improvements in survival, according to a new report. "Over the last 5 years, a greater understanding of the m...

My Strangest Case: The Man With a Heavy Tongue
https://reference.medscape.com/viewarticle/934944_3

Aug 3rd, 2020 - Discussion Four aspects make this case unusual. First, the length of time between the diagnosis and relapse, 40 years, was remarkable. Ordinarily, the prognosis for the patient's original tumor type, follicular thyroid cancer, is excellent; howeve...

Multimodal therapies almost double survival in anaplastic thyroid cancer
https://www.mdedge.com/endocrinology/article/212736/pituitary-thyroid-adrenal-disorders/multimodal-therapies-almost-double?channel=53
Kari Oakes

Nov 20th, 2019 - CHICAGO – Overall survival for patients with anaplastic thyroid cancer was boosted when their care facilitated a rapid work-up, comprehensive treatment planning, and integrated implementation of multimodal therapies. Median survival for participan.

'Dramatic Improvement' in Anaplastic Thyroid Cancer Survival
https://www.medscape.com/viewarticle/921013

Nov 7th, 2019 - CHICAGO — As hope prevails for better outcomes in the management of anaplastic thyroid cancer, experts here at the 89th American Thyroid Association (ATA) Annual Meeting previewed forthcoming new guidelines for this uncommon but highly aggressive ...

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