ALLMedicine™ Autoimmune Lymphoproliferative Syndrome Center
Research & Reviews 329 results
https://doi.org/10.1097/MPH.0000000000002120
Journal of Pediatric Hematology/oncology; Mazzoni M, Dell'Orso G et. al.
Feb 24th, 2021 - Functional variants of the cytotoxic T-lymphocyte antigen-4 (CTLA4) could contribute to the pathogenesis of disorders characterized by abnormal T-cell responses. We report a case of a 13-year-old girl who first presented with polyarticular juvenil...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658692
The Journal of Experimental Medicine; Maccari ME, Fuchs S et. al.
Nov 10th, 2020 - The identification and characterization of rare immune cell populations in humans can be facilitated by their growth advantage in the context of specific genetic diseases. Here, we use autoimmune lymphoproliferative syndrome to identify a populati...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785627
Nephron Lohani S, Sadasivam M et. al.
Oct 15th, 2020 - Collapsing glomerulopathy has multiple associations, including viral infections, medications like bisphosphonates and interferon, autoimmune diseases, and genetic predisposition. We report a case of collapsing focal segmental glomerulosclerosis as...
https://doi.org/10.1080/08820139.2020.1829638
Immunological Investigations; Sharifinejad N, Azizi G et. al.
Oct 13th, 2020 - Protein kinase C is a family of serine/threonine kinases that play a key role in the adaptive immune cell signaling, as well as regulation of growth, apoptosis, and differentiation of a variety of cell types. Patients homozygous for a null mutatio...
https://doi.org/10.1007/s10875-020-00883-7 10.1016/S0092-8674(00)80605-4 10.1016/j.jaci.2012.06.011 10.1182/blood-2011-04-347641 10.1073/pnas.0702975104 10.1182/blood-2010-08-301515 10.1038/nrc1097 10.1111/j.1365-2141.2010.08525.x 10.1182/blood-2014-11-567917 10.1182/blood-2010-07-295501 10.1097/DAD.0000000000001332 10.1182/blood-2014-01-548958 10.1007/s10875-015-0163-3 10.1542/peds.2015-2891 10.1016/j.stemcr.2018.06.008 10.1016/j.clim.2016.12.006 10.1111/cei.12986 10.1097/MPH.0000000000001276 10.1111/ced.13668 10.1186/s12969-019-0346-1 10.1182/blood.V128.22.4268.4268 10.1126/science.286.5445.1735 10.1016/S0092-8674(00)80434-1 10.1016/j.semarthrit.2013.04.009 10.1002/art.40930 10.1002/ajmg.a.35290 10.1182/blood-2006-09-046649 10.1182/blood-2016-03-643544 10.1016/j.leukres.2008.08.022 10.3324/haematol.2009.016865 10.1002/ajmg.c.30300 10.3324/haematol.2014.114595 10.1038/leu.2013.82 10.1182/blood-2017-07-798157 10.1182/blood-2014-09-601690 10.1038/s41467-017-02178-9 10.1038/ng.3420 10.1038/ng.2698 10.1002/pbc.26496
Journal of Clinical Immunology; Neven Q, Boulanger C et. al.
Oct 4th, 2020 - Ras-associated autoimmune leukoproliferative disorder (RALD) is a clinical entity initially identified in patients evaluated for an autoimmune lymphoproliferative syndrome (ALPS)-like phenotype. It remains a matter of debate whether RALD is a chro...
Guidelines 1 results
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953894
Blood Oliveira JB, Bleesing JJ et. al.
Jun 11th, 2010 - Lymphadenopathy in children for which no infectious or malignant cause can be ascertained constitutes a challenging diagnostic dilemma. Autoimmune lymphoproliferative syndrome (ALPS) is a human genetic disorder of lymphocyte apoptosis resulting in...
Clinicaltrials.gov 329 results
https://doi.org/10.1097/MPH.0000000000002120
Journal of Pediatric Hematology/oncology; Mazzoni M, Dell'Orso G et. al.
Feb 24th, 2021 - Functional variants of the cytotoxic T-lymphocyte antigen-4 (CTLA4) could contribute to the pathogenesis of disorders characterized by abnormal T-cell responses. We report a case of a 13-year-old girl who first presented with polyarticular juvenil...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658692
The Journal of Experimental Medicine; Maccari ME, Fuchs S et. al.
Nov 10th, 2020 - The identification and characterization of rare immune cell populations in humans can be facilitated by their growth advantage in the context of specific genetic diseases. Here, we use autoimmune lymphoproliferative syndrome to identify a populati...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785627
Nephron Lohani S, Sadasivam M et. al.
Oct 15th, 2020 - Collapsing glomerulopathy has multiple associations, including viral infections, medications like bisphosphonates and interferon, autoimmune diseases, and genetic predisposition. We report a case of collapsing focal segmental glomerulosclerosis as...
https://doi.org/10.1080/08820139.2020.1829638
Immunological Investigations; Sharifinejad N, Azizi G et. al.
Oct 13th, 2020 - Protein kinase C is a family of serine/threonine kinases that play a key role in the adaptive immune cell signaling, as well as regulation of growth, apoptosis, and differentiation of a variety of cell types. Patients homozygous for a null mutatio...
https://doi.org/10.1007/s10875-020-00883-7 10.1016/S0092-8674(00)80605-4 10.1016/j.jaci.2012.06.011 10.1182/blood-2011-04-347641 10.1073/pnas.0702975104 10.1182/blood-2010-08-301515 10.1038/nrc1097 10.1111/j.1365-2141.2010.08525.x 10.1182/blood-2014-11-567917 10.1182/blood-2010-07-295501 10.1097/DAD.0000000000001332 10.1182/blood-2014-01-548958 10.1007/s10875-015-0163-3 10.1542/peds.2015-2891 10.1016/j.stemcr.2018.06.008 10.1016/j.clim.2016.12.006 10.1111/cei.12986 10.1097/MPH.0000000000001276 10.1111/ced.13668 10.1186/s12969-019-0346-1 10.1182/blood.V128.22.4268.4268 10.1126/science.286.5445.1735 10.1016/S0092-8674(00)80434-1 10.1016/j.semarthrit.2013.04.009 10.1002/art.40930 10.1002/ajmg.a.35290 10.1182/blood-2006-09-046649 10.1182/blood-2016-03-643544 10.1016/j.leukres.2008.08.022 10.3324/haematol.2009.016865 10.1002/ajmg.c.30300 10.3324/haematol.2014.114595 10.1038/leu.2013.82 10.1182/blood-2017-07-798157 10.1182/blood-2014-09-601690 10.1038/s41467-017-02178-9 10.1038/ng.3420 10.1038/ng.2698 10.1002/pbc.26496
Journal of Clinical Immunology; Neven Q, Boulanger C et. al.
Oct 4th, 2020 - Ras-associated autoimmune leukoproliferative disorder (RALD) is a clinical entity initially identified in patients evaluated for an autoimmune lymphoproliferative syndrome (ALPS)-like phenotype. It remains a matter of debate whether RALD is a chro...
News 1 results
https://www.mdedge.com/hematology-oncology/article/187516/anemia/immunosuppressant-can-treat-autoimmune-cytopenias
HT Staff
Oct 27th, 2015 - Red and white blood cells New research suggests the immunosuppressant sirolimus may be a promising treatment option for patients with refractory autoimmune cytopenias. The drug proved particularly effective in children with autoimmune lymphoprolif.