About 390 results

ALLMedicine™ Acral Lentiginous Melanoma Center

Research & Reviews  135 results

Dermoscopy for the Identification of Amelanotic Acral Melanoma.
Journal of the American Podiatric Medical Association; Koblinski JE, Ahrns HT et. al.

Dec 3rd, 2022 - Acral lentiginous melanoma is commonly misdiagnosed, and when detected late it portends a poor prognosis. Acral lentiginous melanoma can be mistaken for verruca, pyogenic granuloma, poroma, an ulcer, or other benign skin conditions. Patients with ...

Developing skin cancer education materials for darker skin populations: crowdsourced de...
Journal of Behavioral Medicine; Upshaw SJ, Jensen JD et. al.

Sep 21st, 2022 - Despite decreased susceptibility, darker skin individuals who develop melanoma have worse survival. This disparity in melanoma mortality is the largest for any cancer, and partly driven by a lack of patient education materials targeted to darker s...

Primary cutaneous melanoma in Black patients: An analysis of 2464 cases from the Nation...
Pigment Cell & Melanoma Research; Fernandez JM, Poling KL et. al.

Sep 17th, 2022 - Melanoma in Black patients carries a poor prognosis. Due to its rarity, melanoma in this population has not been well characterized. This study evaluates survival predictors in Black patients with melanoma. This was a retrospective cohort study of...

Adjuvant nivolumab therapy may not improve disease-free survival in resected acral lent...
Dermatologic Therapy; Maeda T, Yanagi T et. al.

Sep 13th, 2022 - Adjuvant nivolumab therapy has been reported to improve the survival of melanoma patients. Acral lentiginous melanoma (ALM) has been reported to be less likely to respond to immune checkpoint inhibitors (ICIs) than other subtypes. However, the eff...

Lentigo Maligna Melanoma

Aug 24th, 2022 - Overview Lentigo maligna is a subtype of melanoma in situ that is characterized by an atypical proliferation of melanocytes within the basal epidermis; lentigo maligna that invades the dermis is termed lentigo maligna melanoma. [1] Lentigo maligna...

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Clinicaltrials.gov  3 results

Pembrolizumab in Advanced/Metastatic Acral Lentiginous Melanoma

Feb 17th, 2022 - To determine the Overall Response Rate (ORR), as defined as rate of complete response (CR) and partial response (PR) as per RECIST 1.1 in biological treatment-naïve patients with acral lentiginous melanoma treated with pembrolizumab

Study to Investigate the Objective Response Rate of Dabrafenib in Combination With Trametinib in Subjects With BRAF V600 Mutation-Positive Melanoma

Feb 1st, 2022 - This was an open-label, single arm, Phase IIA, multi-center study to evaluate the Objective response rate (ORR) of dabrafenib and trametinib combination therapy in East Asian subjects that have BRAF V600 mutationpositive Stage IIIC (unresectable) ...

A Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With Ipilimumab

Jan 10th, 2020 - Immunotherapy with HD-IL-2 has produced durable benefit in 10% of patients with metastatic cutaneous melanoma. The antitumor activity of IL-2 has been limited at least in part by immunosuppressive and immune-regulatory forces within the tumor micr...

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News  18 results

ASCO 2022: A Beneficial Blend of the Positive and the Negative for Patients With Melanoma

Jul 6th, 2022 - Jeffrey S. Weber, MD, PhD, recounts the conclusions of several neoadjuvant studies presented at ASCO 2022, all of which in their outcomes offer varying degrees of promise for new therapeutic options in the treatment of melanoma. The latest indicat...

Race, Socioeconomic Status Tied to Melanoma Survival

Feb 22nd, 2022 - NEW YORK (Reuters Health) - Race and socioeconomic status are associated with survival from acral lentiginous melanoma (ALM), according to a retrospective study. ALM is a type of melanoma that appears on the palms of the hands, the soles of the fe...

Rare Skin Cancer on Palms and Soles More Likely to Come Back Compared to Other Melanomas

Oct 6th, 2021 - A rare type of melanoma that disproportionately attacks the palms and soles and under the nails of Asians, African-Americans, and Hispanics, who all generally have darker skins, and is not caused by sun exposure, is almost twice as likely to recur...

Melanoma Case Studies Illustrate Factors in Choosing Targeted Therapies

Oct 6th, 2021 - Jeffrey S. Weber, MD, PhD In recent years, advancements in the treatment of patients with metastatic melanoma have proceeded in 2 areas: targeted therapies and immunotherapies. There are now multiple choices in both modalities and, for targeted t...

Pigmented palmar lesions
MDedge Family Medicine;

Apr 22nd, 2021 - Fortunately, the dermoscopy images of these 2 small palmar lesions showed a pattern of pigmentation that aligned in the furrows and was consistent with benign palmar nevi. It is not uncommon to have nevi on the palms or soles of the feet, so it is.

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