About 73 results

ALLMedicine™ Acute Erythroid Leukemia Center

Research & Reviews  28 results

Modeling acute erythroid leukemia via CRISPR.
Blood Zhang JP, Cheng T

Mar 26th, 2021 - Modeling acute erythroid leukemia via CRISPR.|2021|Zhang JP,Cheng T,|

Modeling and targeting of erythroleukemia by hematopoietic genome editing.
Blood Iacobucci I, Qu C et. al.

Jan 30th, 2021 - Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using multiplexed genome editing of mouse hematopoietic stem and progenitor cells and transplant a...

Chemotherapeutics for Acute Erythroid Leukemia: Research, Present and Future.
Current Molecular Medicine; Liao Z, Li J et. al.

Jan 22nd, 2021 - Acute erythroid leukemia (AEL) is a subtype of acute myeloid leukemia (AML) with features such as accumulation of maturation-arrested erythroblasts. Compared with AML, the progression of AEL is faster and the prognosis to available therapy is wors...

Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children's Onc...
Blood Advances; Chisholm KM, Heerema-McKenney AE et. al.

Dec 8th, 2020 - Acute erythroid leukemia (AEL) is a rare subtype of acute myeloid leukemia (AML) primarily affecting older adults and was previously classified into erythroid/myeloid and pure erythroid subtypes. In this pediatric AEL study, we evaluated morpholog...

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Clinicaltrials.gov  1 results

Molecular Characterization of Acute Erythroid Leukemia (M6-AML) Using Targeted Next-generation Sequencing

Aug 10th, 2016 - Acute erythroid leukemia (AEL) is a morphologically distinct, infrequent (o5%) acute myeloid leukemia (AML) designed as M6 in the French- American-British (FAB) classification. The World Health Organization classification recognizes two subclasses...

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