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About 68 results

ALLMedicine™ Acute Leukemia Of Ambiguous Lineage Center

Research & Reviews  17 results

A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation
https://clinicaltrials.gov/ct2/show/NCT04988555

Aug 19th, 2022 - Phase 1 (dose escalation) will determine the recommended Phase 2 dose (RP2D) (i.e. the lowest dose of DSP 5336, that provides the maximum biologic and clinical effect, or the MTD, whichever is lower) in adult patients with relapsed or refractory A...

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage
https://clinicaltrials.gov/ct2/show/NCT03194932

Jul 27th, 2022 - This study will be done in two parts: Part 1 - Dose Escalation: The goal of Part 1 of the study is to find the highest tolerable combination and recommended phase 2 doses (RP2D) of venetoclax plus cytarabine and venetoclax plus cytarabine and idar...

How I Diagnose Acute Leukemia of Ambiguous Lineage.
https://doi.org/10.1093/ajcp/aqac070
American Journal of Clinical Pathology; Weinberg OK, Arber DA

Jul 2nd, 2022 - Classification of acute leukemia involves assigning lineage by resemblance to normal progenitor cells. This approach provides descriptive information about the blast cells that is useful for disease monitoring, provides clues to pathogenesis, and ...

The Myeloid Neoplasms Biology and Outcome Project
https://clinicaltrials.gov/ct2/show/NCT05074316

Oct 12th, 2021 - During recent years, considerable progress has been made in deciphering the molecular genetic and epigenetic basis of myeloid neoplasms and in defining new diagnostic and prognostic as well as predictive markers. Myeloid neoplasms are categorized ...

Red Plaques in a Pediatric Patient With Acute Leukemia of Ambiguous Lineage.
https://doi.org/10.1001/jamaoncol.2020.6134
JAMA Oncology; Wallett A, Manudhane R et. al.

Dec 31st, 2020 - Red Plaques in a Pediatric Patient With Acute Leukemia of Ambiguous Lineage.|2020|Wallett A,Manudhane R,Lipsett J,|

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Clinicaltrials.gov  5 results

A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation
https://clinicaltrials.gov/ct2/show/NCT04988555

Aug 19th, 2022 - Phase 1 (dose escalation) will determine the recommended Phase 2 dose (RP2D) (i.e. the lowest dose of DSP 5336, that provides the maximum biologic and clinical effect, or the MTD, whichever is lower) in adult patients with relapsed or refractory A...

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage
https://clinicaltrials.gov/ct2/show/NCT03194932

Jul 27th, 2022 - This study will be done in two parts: Part 1 - Dose Escalation: The goal of Part 1 of the study is to find the highest tolerable combination and recommended phase 2 doses (RP2D) of venetoclax plus cytarabine and venetoclax plus cytarabine and idar...

The Myeloid Neoplasms Biology and Outcome Project
https://clinicaltrials.gov/ct2/show/NCT05074316

Oct 12th, 2021 - During recent years, considerable progress has been made in deciphering the molecular genetic and epigenetic basis of myeloid neoplasms and in defining new diagnostic and prognostic as well as predictive markers. Myeloid neoplasms are categorized ...

Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage
https://clinicaltrials.gov/ct2/show/NCT04440267

Jun 19th, 2020 - In this prospective, single arm, open label, clinical trial, a total of 50 acute leukemia of ambiguous lineage patients will be enrolled. Patients will receive acute lymphoblastic leukemia (ALL) -based chemotherapy and are permitted to receive all...

Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
https://clinicaltrials.gov/ct2/show/NCT00372619

Jun 5th, 2017 - OBJECTIVES: Primary To define the overall response rate (complete remission or remission without platelet recovery) in young patients with relapsed or refractory acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) treated with clofa...

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News  5 results

Acute Leukemia: 5 Things to Know
https://www.medscape.com/viewarticle/922399_2

Dec 13th, 2019 - 3. New research points to previously unknown risk factors for acute leukemia. Researchers have recently uncovered risk factors for AML and acute lymphocytic leukemia (ALL). A 2019 cohort study found that patients receiving chemotherapy for almost ...

Acute Leukemia of Ambiguous Lineage in Elderly Patients: A SEER-Medicare Database Analysis
https://www.mdedge.com/fedprac/avaho/article/143946/leukemia-myelodysplasia-transplantation/acute-leukemia-ambiguous
Guru Subramanian Guru Murthy

Aug 10th, 2018 - About Research in Context In this article, the authors of recent scholarship have been asked to discuss the implications of their research on federal health care providers and specifically the veteran and active-duty service member patient populat.

Advances in Hematology and Oncology (August 2017)
https://www.mdedge.com/fedprac/article/145885/advances-hematology-and-oncology-august-2017

Aug 2nd, 2017 - Table of Contents The Challenges of Precision Medicine and New Advances in Molecular Diagnostic Testing in Hematolymphoid Malignancies: Impact on the VHA Systems Automation for Cancer Surveillance: A Lean Six Sigma Project for Tracking Care of Pat.

Genetic Testing in the Diagnosis and Biology of Acute Leukemia
https://www.medscape.com/viewarticle/916507

Abstract and Introduction Abstract Objectives: The 2017 Workshop of the Society for Hematopathology/European Association for Haematopathology examined the role of molecular genetics in the diagnosis and biology of acute leukemia. Methods: Acute le...

Genetic Testing in the Diagnosis and Biology of Acute Leukemia
https://www.medscape.com/viewarticle/916507_1

Abstract and Introduction Abstract Objectives: The 2017 Workshop of the Society for Hematopathology/European Association for Haematopathology examined the role of molecular genetics in the diagnosis and biology of acute leukemia. Methods: Acute le...

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