About 23,820 results

ALLMedicine™ Acute Myeloid Leukemia Center

Research & Reviews  8,718 results

Probing RNA-Binding Proteins in Cancer.
Cancer Discovery;

Sep 23rd, 2021 - As interest grows in better understanding the highly complex post-transcriptional environment in tumors, RNA-binding proteins have emerged as a class of potential cancer therapeutic targets. Recent research implicates them in MYC-driven cancers an...

Acute Myeloid Leukemia Presenting as a Posterior Fossa Tumor.
Journal of Pediatric Hematology/oncology; Vanan MI, Li J et. al.

Sep 23rd, 2021 - Extramedullary leukemia in pediatric acute myeloid leukemia can manifest as a myeloid sarcoma (MS), also known as granulocytic sarcoma or chloroma, in a variety of sites, or as leukemic blasts in the cerebrospinal fluid. Isolated MS of the central...

Alteration of PPAR-GAMMA (PPARG; PPARγ) and PTEN gene expression in acute myeloid leuke...
Molecular Genetics & Genomic Medicine; Esmaeili S, Salari S et. al.

Sep 23rd, 2021 - In the new era of tailored cancer treatment strategies, finding a molecule to regulate a wide range of intracellular functions is valuable. The unique property of nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ; PPARG) in tran...

Myelodysplastic Syndromes: A New Decade.
Clinical Lymphoma, Myeloma & Leukemia; Volpe VO, Garcia-Manero G et. al.

Sep 22nd, 2021 - Myelodysplastic syndromes (MDS) are a group of heterogeneous clonal hematopoietic stem cell disorders. The 2020 Surveillance, Epidemiology, and End Results data demonstrates the incidence rate of MDS increases with age especially in those greater ...

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Guidelines  10 results

Hematopoietic Cell Transplantation in the Treatment of Newly Diagnosed Adult Acute Myel...
Biology of Blood and Marrow Transplantation : Journal of ... Dholaria B, Savani BN et. al.

Sep 24th, 2020 - The role of hematopoietic cell transplantation (HCT) in the management of newly diagnosed adult acute myeloid leukemia (AML) is reviewed and critically evaluated in this evidence-based review. An AML expert panel, consisting of both transplant and...

NCCN Guidelines Insights: Myeloproliferative Neoplasms, Version 2.2018.
Journal of the National Comprehensive Cancer Network : JN... Mesa RA, Jamieson C et. al.

Oct 7th, 2017 - Myeloproliferative neoplasms (MPNs) are a group of heterogeneous disorders of the hematopoietic system that include myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET). PV and ET are characterized by significant thromboh...

Acute Myeloid Leukemia, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology.
Journal of the National Comprehensive Cancer Network : JN... O'Donnell MR, Tallman MS et. al.

Jul 9th, 2017 - Acute myeloid leukemia (AML) is the most common form of acute leukemia among adults and accounts for the largest number of annual deaths due to leukemias in the United States. This portion of the NCCN Guidelines for AML focuses on management and p...

Acute myeloid leukemia, version 2.2013.
Journal of the National Comprehensive Cancer Network : JN... O'Donnell MR, Tallman MS et. al.

Sep 14th, 2013 - These NCCN Guidelines Insights summarize several key updates to the NCCN Guidelines for Acute Myeloid Leukemia and discuss the clinical evidence that support the recommendations. The updates described in this article focus on the acute promyelocyt...

Myelodysplastic syndromes: clinical practice guidelines in oncology.
Journal of the National Comprehensive Cancer Network : JN... Greenberg PL, Attar E et. al.

Jul 13th, 2013 - The myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematopoietic disorders characterized by cytopenias, dysplasia in one or more myeloid lineages, and the potential for development of acute myeloid leukemia. These disord...

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Drugs  28 results see all →

News  771 results

Ficlatuzumab Plus Chemo Shows Early Promise in Refractory AML

Jul 21st, 2021 - NEW YORK (Reuters Health) - The combination of ficlatuzumab plus chemotherapy showed considerable early promise in relapsed/refractory acute myeloid leukemia (AML) in a small phase-1 study. "The high rate of complete remissions was surprising to u...

Hypomethylating Agents in Children With Relapsed/Refractory AML

Jun 25th, 2021 - Hypomethylating agents are generally considered to be agents of choice for older adults with acute myeloid leukemia who cannot tolerate the rigors of more intensive therapies, but HMAs also can serve as a bridge to transplant for children and youn...

Reduced-Intensity Transplant Benefits Older Patients With AML

Jun 21st, 2021 - Among older patients with acute myeloid leukemia (AML), survival is significantly better when they undergo reduced-intensity condition (RIC) before receiving an allogeneic hematopoietic cell transplant (HCT) at first remission. This improvement in...

Fast Five Quiz: Myelodysplastic Syndrome Presentation and Diagnosis

May 12th, 2021 - Myelodysplastic syndrome (MDS) is a group of related disorders that arise as the result of distorted hematopoietic stem cell function, inflammatory and innate immune deregulation, and multiple genomic events. These molecular alterations increase t...

Whole-Genome Sequencing Emerging for Routine Cancer Care

Mar 11th, 2021 - Almost 20 years after the human genome was first mapped, whole-genome sequencing might finally be ready to enter routine cancer care. Researchers at Washington University in St. Louis, St. Louis, Missouri, are commercializing an automated sequenci...

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Patient Education  1 results see all →