ALLMedicine™ Anaplastic Oligoastrocytoma Center
Research & Reviews 41 results
https://clinicaltrials.gov/ct2/show/NCT02942264
Sep 28th, 2021 - Background: Zotiraciclib (TG02) is a pyrimidine-based multi-kinase inhibitor that has been shown to have inhibitory effects on cyclin-dependent kinases (CDKs), Janus Kinase 2 (JAK2) and Fm-like tyrosine kinase 3 (Flt3). It is orally administered a...
http://emedicine.medscape.com/article/342958-overview
Jul 16th, 2020 - Practice Essentials Oligodendroglioma is a well-differentiated, diffusely infiltrating tumor of adults that is typically located in the cerebral hemispheres and is predominantly composed of cells that morphologically resemble oligodendroglia. [1, ...
https://emedicine.medscape.com/article/342958-print
Jul 16th, 2020 - Oligodendroglioma is a well-differentiated, diffusely infiltrating tumor of adults that is typically located in the cerebral hemispheres and is predominantly composed of cells that morphologically resemble oligodendroglia.[1, 2] The hallmark molec...
https://emedicine.medscape.com/article/342958-overview
Jul 16th, 2020 - Practice Essentials Oligodendroglioma is a well-differentiated, diffusely infiltrating tumor of adults that is typically located in the cerebral hemispheres and is predominantly composed of cells that morphologically resemble oligodendroglia. [1, ...
http://emedicine.medscape.com/article/2006770-overview
Oct 15th, 2019 - Grading of Brain Tumors The widely used tumor-node-metastasis (TNM) classification system was found to be inappropriate for brain tumors, as tumor size is less relevant than tumor histology and location, the brain has no lymphatics, and most of th...
Guidelines 1 results
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785606
Clinical & Translational Oncology : Official Publication ... Balañá C, Alonso M et. al.
Oct 24th, 2017 - The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnos...
Clinicaltrials.gov 6 results
https://clinicaltrials.gov/ct2/show/NCT02942264
Sep 28th, 2021 - Background: Zotiraciclib (TG02) is a pyrimidine-based multi-kinase inhibitor that has been shown to have inhibitory effects on cyclin-dependent kinases (CDKs), Janus Kinase 2 (JAK2) and Fm-like tyrosine kinase 3 (Flt3). It is orally administered a...
https://clinicaltrials.gov/ct2/show/NCT01004887
Jan 17th, 2019 - OBJECTIVES: To evaluate the diagnostic and prognostic relevance of various molecular, cytogenetic, and other tumor markers in high-grade glioma in paraffin-embedded tissue collected from patients enrolled in the Mayo Clinic or North Central Cancer...
https://clinicaltrials.gov/ct2/show/NCT03068520
Mar 21st, 2017 - The multimodality approach for management of primary and secondary brain tumors includes surgery, radiotherapy and chemotherapy. Determination of an objective response to treatment relies on imaging findings (e.g. CT, MRI, PET).During the course o...
https://clinicaltrials.gov/ct2/show/NCT00859222
Mar 14th, 2017 - Phase I Primary Objective • To determine the maximum tolerated dose (MTD) of LBH589 in combination with bevacizumab given at 10 mg/kg every 2 weeks in patients with recurrent glioblastoma (GBM), gliosarcoma, anaplastic astrocytoma, anaplastic olig...
https://clinicaltrials.gov/ct2/show/NCT01847235
Apr 26th, 2016 - Patient with relapsed or advanced anaplastic oligodendroglioma and anaplastic oligoastrocytoma will be enrolled. Enrolled patients will begin on temozolomide 200 mg/m2/d in a fasting state for 5 consecutive days (1,000 mg/m2 per 28-day cycle). Pat...
News 1 results
https://www.onclive.com/view/toca-511-shows-promise-in-highgrade-glioma
Dec 20th, 2020 - Timothy Cloughesy, MD The gene for an anticancer drug was successfully transduced in high-grade gliomas, according to data from a phase I trial of Toca 511 presented at the 2016 Society for Neuro-Oncology Annual Meeting. Additionally, the median ...