ALLMedicine™ Anaplastic Oligodendroglioma Center

Apr 4th, 2022 - Patients will be stratified by the molecular and histologic characteristics of their tumor to one of three treatment strata. STRATUM A: Combination Treatment: ribociclib and gemcitabine. Patient Population: Participants with a diagnosis of refract...

Mar 19th, 2022 - 5-Aminolevulinic acid (5-ALA)-enhanced fluorescence-guided resection of high-grade glioma (HGG) using microscopic blue light visualization offers the ability to improve extent of resection (EOR); however, few descriptions of HGG resection performe...

Mar 17th, 2022 - PRIMARY OBJECTIVES: I. To evaluate toxicity and estimate the maximum tolerated dose (MTD) of melphalan (intra-arterially [i.a.]) administered in conjunction with carboplatin (i.a.) and etoposide phosphate (intravenously [i.v.]) undergoing BBBD, in...

Mar 3rd, 2022 - Complete deletion of both the short arm of chromosome 1 (1p) and the long arm of chromosome 19 (19q), known as 1p/19q codeletion, is a mutation that can occur in gliomas. It occurs in a type of glioma known as oligodendroglioma and its higher grad...

Jan 15th, 2022 - The impact of near-total resection of IDH-mutated anaplastic glioma (IDHmutAG) is well-established but there remains uncertainty of benefit in tumours of the insular cortex where the extent of safe resection may be limited. This study aimed to ass...

Sep 14th, 2013 - Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemothera...

Apr 4th, 2022 - Patients will be stratified by the molecular and histologic characteristics of their tumor to one of three treatment strata. STRATUM A: Combination Treatment: ribociclib and gemcitabine. Patient Population: Participants with a diagnosis of refract...

Mar 17th, 2022 - PRIMARY OBJECTIVES: I. To evaluate toxicity and estimate the maximum tolerated dose (MTD) of melphalan (intra-arterially [i.a.]) administered in conjunction with carboplatin (i.a.) and etoposide phosphate (intravenously [i.v.]) undergoing BBBD, in...

Oct 8th, 2021 - The purpose of this study is to see how effective treatment of high doses of chemotherapy is for your tumor. We will also be looking at the side effects and risks of this treatment. You will receive very high doses of chemotherapy. High doses of c...

Apr 8th, 2020 - OBJECTIVES: I. Determine the efficacy of topotecan in patients with recurrent anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma. II. Determine the qualitative and quantitative toxicity of topotecan in this patient population on thi...

Sep 18th, 2018 - OBJECTIVES: Determine progression-free survival of patients with newly diagnosed anaplastic oligodendroglioma (AO) or mixed oligoastrocytoma (MOA) treated with temozolomide. Determine the response rate in these patients. Assess the quality of life...

Jul 26th, 2012 - Andrew L. Pecora, MD Editor-in-Chief Oncology & Biotech News Chief Innovations Officer, Professor, and Vice President of Cancer Services John Theurer Cancer Center at Hackensack University Medical Center I am sure any of us can think of many other...

Case Report A thunderclap headache is a severe headache with sudden onset similar to a clap of thunder, with a maximum intensity within 1 minute. The primary types (thunderclap, cough, exertional, and sexual) can recur intermittently and are gener...

Discussion Although Day and Raskin[1] initially coined the term thunderclap headache to refer to the headache associated with an unruptured aneurysm, the most common secondary cause is subarachnoid hemorrhage. Other secondary causes include cerebr...