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About 64,905 results

ALLMedicine™ Hepatocellular Carcinoma Center

Research & Reviews  23,903 results

Novel approaches in search for biomarkers of cholangiocarcinoma.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048460
World Journal of Gastroenterology; Mocan LP, Ilieș M et. al.

May 19th, 2022 - Cholangiocarcinoma (CCA) arises from the ductular epithelium of the biliary tree, either within the liver (intrahepatic CCA) or more commonly from the extrahepatic bile ducts (extrahepatic CCA). This disease has a poor prognosis and a growing worl...

Identification and validation of the N6-methyladenosine RNA methylation regulator ZC3H1...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108408
International Journal of Medical Sciences; Wu S, He G et. al.

May 19th, 2022 - N6-methyladenosine (m6A) RNA methylation has been implicated in various malignancies. This study aimed to identify prognostic signature based on m6A methylation regulators for hepatocellular carcinoma (HCC) and provide candidate targets for HCC tr...

Meat Intake and the Risk of Hepatocellular Carcinoma: A Meta-Analysis of Observational ...
https://doi.org/10.1080/01635581.2022.2077386
Nutrition and Cancer; Yu J, Liu Z et. al.

May 19th, 2022 - The association between meat intake and hepatocellular carcinoma (HCC) risk is still unclear. We conducted a meta-analysis with observational studies to clarify this relationship. A total of 17 studies involving 2,915,680 participants and 4,953 ca...

Impact of lenvatinib on renal function compared to sorafenib for unresectable hepatocel...
https://doi.org/10.1097/MD.0000000000029289
Medicine Sasaki R, Fukushima M et. al.

May 19th, 2022 - Anti-VEGF drugs, such as tyrosine kinase inhibitors, play an important role in systemic therapy for unresectable hepatocellular carcinoma (uHCC). We examined the effects of sorafenib and lenvatinib on proteinuria and renal function.Patients who we...

A prognostic signature based on the expression profile of the ferroptosis-related long ...
https://doi.org/10.17219/acem/149566
Advances in Clinical and Experimental Medicine : Official... Lin X, Yang S

May 19th, 2022 - Ferroptosis is a special form of cell death with extensive biological associations with various cancers; however, the role of aberrantly expressed ferroptosis-related long non-coding RNAs (lncRNAs) in hepatocellular carcinoma (HCC) remains unclear...

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Guidelines  35 results

AGA Clinical Practice Guideline on Systemic Therapy for Hepatocellular Carcinoma.
https://doi.org/10.1053/j.gastro.2021.12.276
Gastroenterology Su GL, Altayar O et. al.

Feb 26th, 2022 - Hepatocellular carcinoma (HCC), the most common primary liver cancer, remains a deadly cancer, with an incidence that has tripled in the United States since 1980. In recent years, new systemic therapies for HCC have been approved and a critical as...

Non-alcoholic fatty liver disease in adults 2021: A clinical practice guideline of the ...
https://doi.org/10.1016/j.numecd.2021.04.028
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; , et. al.

Dec 21st, 2021 - Nonalcoholic fatty liver disease (NAFLD) is a common and emerging liver disease in adults, paralleling the epidemic of obesity and diabetes, and leading to worrisome events (hepatocellular carcinoma and end-stage liver disease). In the last years,...

External Beam Radiation Therapy for Primary Liver Cancers: An ASTRO Clinical Practice G...
https://doi.org/10.1016/j.prro.2021.09.004
Practical Radiation Oncology; Apisarnthanarax S, Barry A et. al.

Oct 25th, 2021 - This guideline provides evidence-based recommendations for the indications and technique-dose of external beam radiation therapy (EBRT) in hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (IHC). The American Society for Radiation...

Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
https://doi.org/10.1016/j.clinre.2021.101771
Clinics and Research in Hepatology and Gastroenterology; Tran A, Shili-Masmoudi S et. al.

Aug 1st, 2021 - Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Clinical care for patients with HCV-related liver disease has advanced considerably with developments in screening, diagnostic procedures to evaluate liver fibrosis and i...

Non-invasive diagnosis and follow-up in liver transplantation.
https://doi.org/10.1016/j.clinre.2021.101774
Clinics and Research in Hepatology and Gastroenterology; Dumortier J, Besch C et. al.

Aug 1st, 2021 - The field of liver transplantation directly or indirectly embodies all liver diseases, in addition to specific ones related to organ rejection (cellular and humoral). The recommended non-invasive methods for determining the indication for liver tr...

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Drugs  19 results see all →

Clinicaltrials.gov  776 results

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
https://clinicaltrials.gov/ct2/show/NCT03520660

May 13th, 2022 - We intend to enroll up to 350 subjects with chronic hepatitis C virus (HCV) infection. Subjects will be recruited from two sources: Phase I: treatment naive or experienced who have failed a prior treatment (including DAA-experienced) who are willi...

LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment With Transarterial Embolization (TAE) Alone or Combined With Thermal Ablation
https://clinicaltrials.gov/ct2/show/NCT02649868

May 13th, 2022 - Background: Hepatocellular Carcinoma (HCC) is the 3rd most common cause of cancer globally with an increasing incidence worldwide. Management of hepatic malignancies from primary Hepatocellular Carcinoma (HCC) or metastatic disease involves a mult...

Electromagnetic Fields Versus Placebo as Third-line Therapy For Patients With Advanced Hepatocellular Carcinoma
https://clinicaltrials.gov/ct2/show/NCT04797884

May 13th, 2022 - Primary Objective: To estimate overall survival and quality of life. Secondary Objectives To estimate progression-free survival To evaluate safety and tolerability in this patient population. To evaluate the effect on levels of alpha-fetoprotein.

MANDARIN (S6371)
https://clinicaltrials.gov/ct2/show/NCT05016245

May 13th, 2022 - To evaluate the efficacy and safety of TheraSphereTM yttrium [90Y] glass microsphere in the Chinese patients with inoperable hepatocellular carcinoma.

Evaluation of Patients With Liver Disease
https://clinicaltrials.gov/ct2/show/NCT00001971

May 13th, 2022 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...

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News  1,225 results

TIPS plus sequential systemic therapy shows promise in advanced HCC with tumor thrombus-related SPH
https://www.mdedge.com/gihepnews/article/254679/hepatocellular-carcinoma/tips-plus-sequential-systemic-therapy-shows

May 17th, 2022 - Key clinical point: Transjugular intrahepatic portosystemic shunt (TIPS) plus sequential systemic therapy is safe and feasible for treating portal vein tumor thrombus (PVTT)-related symptomatic portal hypertension (SPH) in advanced hepatocellular.

Psychosocial Barriers and Their Impact on Hepatocellular Carcinoma Care in US Veterans: Tumor Board Model of Care
https://www.mdedge.com/fedprac/article/254637/hepatocellular-carcinoma/psychosocial-barriers-and-their-impact
Parul D. Agarwal, MD, Beth A. Haftoglou, RN et. al.

May 16th, 2022 - Hepatocellular carcinoma (HCC) remains a major global health problem and is the third leading cause of cancer-related mortality worldwide. 1 Management of HCC is complex; as it largely occurs in the background of chronic liver disease, its manageme.

Liquid Biopsy in HCC Offers Valuable Tool for Detection, Disease Monitoring
https://www.medscape.com/viewarticle/972934

Apr 29th, 2022 - Liquid biopsy using circulating tumor (ctDNA) detection and profiling is a valuable tool for clinicians in monitoring hepatocellular carcinoma (HCC), particularly in monitoring progression, researchers wrote in a recent review. Details of the revi...

What Gastroenterologists Need to Know About New Guidelines on Systemic HCC Therapy
https://www.medscape.com/viewarticle/972626

Apr 29th, 2022 - Since 1980, the incidence of hepatocellular carcinoma (HCC) has tripled in the United States. The uptick in this deadly liver cancer was thankfully accompanied by the introduction of new and improved methods of treating it. Recent years have seen ...

Microbiota Modulation Offers Hope of Expanding the Benefits of Immunotherapy
https://www.onclive.com/view/microbiota-modulation-offers-hope-of-expanding-the-benefits-of-immunotherapy

Apr 28th, 2022 - Although the microorganisms colonizing our bodies have long been linked to human health and various disease states, an understanding of the potential impact of the microbiota on cancer has just begun to emerge in the past 20 years. Novel strategie...

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Patient Education  4 results see all →