ALLMedicine™ Alopecia Universalis Center
Research & Reviews 82 results
https://doi.org/10.1111/jocd.14541
Journal of Cosmetic Dermatology; Aldaffaie STH, Hussein TA et. al.
Nov 4th, 2021 - Alopecia areata is considered to be an autoimmune disease characterized by T-cell response and production of cytokines around the anagen stage. The aim of this study was to assess T cells in blood using immune biomarkers (CD3, CD4, and CD8) in pat...
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Clinical Reviews in Allergy & Immunology; Zhou C, Li X et. al.
Aug 18th, 2021 - Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease, resulting in hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has still remained elusive, while the common theory is the collapse ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305636
International Journal of Environmental Research and Publi... Borriello G, Ianniello A et. al.
Jul 25th, 2021 - Alopecia Universalis (AU) is the most severe form of Alopecia Areata and is caused by cytotoxic T-cells reacting with follicular autoantigens, producing complete loss of scalp and body hair. Alemtuzumab is a highly efficacious monoclonal antibody ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601666
The American Journal of Dermatopathology; Kossard S, Sheriff T et. al.
Jun 17th, 2021 - The definition of IgG4-related diseases incorporates a broad range of systemic diseases particularly a subset dominated by fibroinflammation. CD4+cytotoxic T cells have emerged as the major driving force for the fibroinflammation, and the pathogen...
https://doi.org/10.1159/000515764
Dermatology (Basel, Switzerland); Zhang T, Nie Y
May 19th, 2021 - Alopecia areata (AA) is an autoimmune disease typified by nonscarring hair loss with a variable clinical course. Although there is an increased understanding of AA pathogenesis and progress in its treatments, the outcome of AA patients remains unf...
Clinicaltrials.gov 3 results
https://clinicaltrials.gov/ct2/show/NCT02599129
Mar 11th, 2021 - Alopecia areata is a medical condition, in which the hair falls out in patches. The hair can fall out on the scalp or elsewhere on the face and body. Alopecia areata is an autoimmune skin disease, which means that the immune system is recognizing ...
https://clinicaltrials.gov/ct2/show/NCT01898806
Jun 6th, 2019 - Alopecia areata (AA) is a major medical problem and is the most prevalent autoimmune disease in the US. AA represents the second most common form of hair loss and causes significant disfigurement and psychological distress to affected individuals....
https://clinicaltrials.gov/ct2/show/NCT00069589
May 14th, 2019 - Alopecia areata is a condition in which hair is lost either from part of the scalp, all of the scalp, or the entire body, and it affects 1% to 2% of the population. It is thought to be an autoimmune disease and in some cases the disease is heredit...
News 18 results
https://www.medscape.com/viewarticle/960162
Oct 4th, 2021 - Baricitinib, an oral inhibitor of Janus kinase (JAK) types 1 and 2, produced substantial rates of hair growth with acceptable tolerability for patients with alopecia areata, according to the results of two phase 3 trials presented at the European ...
https://www.mdedge.com/dermatology/article/208895/pediatrics/review-looks-natural-course-alopecia-areata-young-children
Jake Remaly
Sep 26th, 2019 - Most children who develop alopecia areata before age 4 years have mild disease with less than 50% hair loss, and present between ages 2 and 4, according to a retrospective chart review of 125 children. Almost 90% of the children presented between.
https://www.medscape.com/viewarticle/910163
Mar 11th, 2019 - The Janus kinase (JAK) inhibitor CTP-543 (Concert Pharmaceuticals) is effective for the treatment of moderate to severe alopecia areata, according to interim results from a phase 2a randomized safety and efficacy study (NCT03137381). "We've identi...
https://www.staging.medscape.com/viewarticle/902077
Sep 17th, 2018 - PARIS — Two investigational oral Janus kinase (JAK) inhibitors are safe and effective for patients with moderate to severe hair loss, according to 24-week interim findings from a randomized, double-blind, placebo-controlled, multicenter phase 2 tr...
https://www.medscape.com/viewarticle/902077
Sep 17th, 2018 - PARIS — Two investigational oral Janus kinase (JAK) inhibitors are safe and effective for patients with moderate to severe hair loss, according to 24-week interim findings from a randomized, double-blind, placebo-controlled, multicenter phase 2 tr...
