×
About 320 results

ALLMedicine™ Amyopathic Dermatomyositis Center

Research & Reviews  110 results

Two Distinct Immune Cell Signatures Predict the Clinical Outcomes in Patients with Amyo...
https://doi.org/10.1002/art.42264
Arthritis & Rheumatology (Hoboken, N.J.); Ye Y, Zhang X et. al.

Jun 18th, 2022 - Amyopathic dermatomyositis (ADM) is a heterogeneous and life-threatening autoimmune disease with high mortality. In particular, anti-MDA5 antibody-positive patients are at high risk of developing rapidly progressive interstitial lung disease (ILD)...

Development of organ-specific autoimmunity by dysregulated Aire expression.
https://doi.org/10.1111/imcb.12546
Immunology and Cell Biology; Nishijima H, Sugita M et. al.

Mar 22nd, 2022 - Deficiency for AIRE/Aire in both humans and mice results in the development of organ-specific autoimmune disease. We tested whether augmented and/or dysregulated AIRE/Aire expression might be also prone to the breakdown of self-tolerance. To defin...

Clinical spectrum time course in non-Asian patients positive for anti-MDA5 antibodies.
https://doi.org/10.55563/clinexprheumatol/di1083
Clinical and Experimental Rheumatology; Cavagna L, Meloni F et. al.

Feb 25th, 2022 - To define the clinical spectrum time-course and prognosis of non-Asian patients positive for anti-MDA5 antibodies. We conducted a multicentre, international, retrospective cohort study. 149 anti-MDA5 positive patients (median onset age 53 years, m...

Anti-Ro52 antibodies are associated with the prognosis of adult idiopathic inflammatory...
https://doi.org/10.1093/rheumatology/keac090
Rheumatology (Oxford, England); Gui X, Shenyun S et. al.

Feb 12th, 2022 - In the present study, we aimed to assess the prevalence and clinical significance of anti-Ro52 antibodies in a cohort of patients with idiopathic inflammatory myopathy-associated interstitial lung disease (IIM-ILD) with different myositis-specific...

see more →

Clinicaltrials.gov  5 results

Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis
https://clinicaltrials.gov/ct2/show/NCT02245841

Sep 16th, 2021 - Adult and juvenile dermatomyositis (DM) are systemic immune-mediated inflammatory diseases most commonly affecting the skin and musculoskeletal system. Amyopathic dermatomyositis is a subtype of dermatomyositis that affects only the skin and lacks...

The Efficacy and Safety of JAK Inhibitor in the Treatment of Anti-MDA5 Antibody-positive Dermatomyositis Patients
https://clinicaltrials.gov/ct2/show/NCT04966884

Jul 19th, 2021 - Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by chronic inflammation in the skin and muscle. Anti-melanoma differentiation-associated gene5 (Anti-MDA5) antibody positive DM is a subtype of DM that is more frequent in E...

Correlation Between the Change of Peripheral Lymphocyte Subsets and Clinically Amyopathic Dermatomyositis Combined With Rapidly Progressive Interstitial Lung Disease
https://clinicaltrials.gov/ct2/show/NCT04613219

Nov 3rd, 2020 - Acute respiratory distress syndrome (ARDS) occurs in Clinically Amyopathic Dermatomyisitis(CADM) combined with Rapidly Progressive Interstitial Lung Disease(RPILD) within 1-3 months, which leads to death of patients and is difficult to treat. Even...

Basiliximab Treating Interstitial Pneumonia of CADM
https://clinicaltrials.gov/ct2/show/NCT03192657

Jun 20th, 2017 - This is a 52-week, randomized, open and routine treatment controlled study. This study will assess the safety and efficacy of basiliximab as an add-on treatment for interstitial pneumonia in clinical amyopathic dermatomyositis (CADM) patients. 100...

Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis
https://clinicaltrials.gov/ct2/show/NCT02821689

Jul 1st, 2016 - Interstitial lung disease (ILD) is a common complication of dermatomyositis (DM) with prevalence up to 65%, and is considered to be one of the determining factors of prognosis. Clinical amyopathic dermatomyositis (CADM), which is a special phenoty...

see more →

News  13 results

Validity of commercial serologic tests for dermatomyositis still questionable
https://www.mdedge.com/dermatology/article/249093/autoimmune-diseases/validity-commercial-serologic-tests-dermatomyositis
Doug Brunk

Nov 24th, 2021 - Clinical assessment for pulmonary disease and malignancy in patients with dermatomyositis should not be replaced with serologic tests at this time, according to Jeffrey P. Callen, MD.

Papules and Telangiectases on the Distal Fingers of a Child
https://www.mdedge.com/dermatology/article/198446/pediatrics/papules-and-telangiectases-distal-fingers-child?channel=113
Briana Brown, DO, Jacqueline Jones, DO et. al.

Apr 8th, 2019 - The Diagnosis: Juvenile Dermatomyositis Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory myopathy of childhood that is autoimmune in nature with an annual incidence ranging from 2. 5 to 4.

Papules and Telangiectases on the Distal Fingers of a Child
https://www.mdedge.com/dermatology/article/198446/pediatrics/papules-and-telangiectases-distal-fingers-child
Briana Brown, DO, Jacqueline Jones, DO et. al.

Apr 8th, 2019 - The Diagnosis: Juvenile Dermatomyositis Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory myopathy of childhood that is autoimmune in nature with an annual incidence ranging from 2. 5 to 4.

Timely dermatomyositis diagnosis, treatment remain elusive
https://www.mdedge.com/dermatology/article/167148/lupus-connective-tissue-diseases/timely-dermatomyositis-diagnosis/page/0/1

Jun 3rd, 2018 - “We saw that there was a much higher rate of misdiagnosis in patients who didn’t have any muscle disease. We have to raise awareness that amyopathic dermatomyositis is a very prevalent condition,” Dr.

Timely dermatomyositis diagnosis, treatment remain elusive
https://www.mdedge.com/rheumatology/article/167148/lupus-connective-tissue-diseases/timely-dermatomyositis-diagnosis
M. Alexander Otto

Jun 3rd, 2018 - ORLANDO – There was a median 1-year delay between the onset of symptoms and diagnosis of classic dermatomyositis, and a 17-month delay before diagnosis of amyopathic dermatomyositis, based on a review of 232 dermatomyositis patients seen at the Un.

see more →