About 5,943 results

ALLMedicine™ Dermatomyositis Center

Research & Reviews  1,924 results

Current and new targets for treating myositis.
Current Opinion in Pharmacology; Moghadam-Kia S, Oddis CV

Jun 21st, 2022 - As treatment of refractory idiopathic inflammatory myopathies (IIM) has been challenging, there is growing interest in assessing new therapies that target various pathways implicated in the pathogenesis of IIM. In the largest clinical trial to dat...

Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers.
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Clinical Reviews in Allergy & Immunology; Cavazzana I, Vojinovic T et. al.

Jun 19th, 2022 - Disease-specific autoantibodies are considered the most important biomarkers for systemic sclerosis (SSc), due to their ability to stratify patients with different severity and prognosis. Anti-nuclear antibodies (ANA), occurring in subjects with i...

Two Distinct Immune Cell Signatures Predict the Clinical Outcomes in Patients with Amyo...
Arthritis & Rheumatology (Hoboken, N.J.); Ye Y, Zhang X et. al.

Jun 18th, 2022 - Amyopathic dermatomyositis (ADM) is a heterogeneous and life-threatening autoimmune disease with high mortality. In particular, anti-MDA5 antibody-positive patients are at high risk of developing rapidly progressive interstitial lung disease (ILD)...

Combination therapy of tacrolimus, high doses of glucocorticosteroids, and cyclophospha...
Medicine Li L, Li M et. al.

Jun 18th, 2022 - The high-dose glucocorticosteroid (GC) treatment is the first choice for dermatomyositis complicated with interstitial lung disease (DM-ILD) but patients are resistant to the high-dose GC monotherapy. Besides, the high dose of GC, the secondary im...

A Study In Adults With Moderate To Severe Dermatomyositis

Jun 16th, 2022 - A Study looking at Investigational drug and Placebo administered to adult Patients with moderate to severe Dermatomyositis

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Guidelines  3 results

Treatment consensus for management of polymyositis and dermatomyositis among rheumatolo...
The Journal of Dermatology; Kohsaka H, Mimori T et. al.

Dec 19th, 2018 - Although rheumatologists, neurologists and dermatologists see patients with polymyositis (PM) and dermatomyositis (DM), their management appears to vary depending on the physician's specialty. The aim of the present study was to establish the trea...

2016 American College of Rheumatology/European League Against Rheumatism Criteria for M...
Annals of the Rheumatic Diseases; Rider LG, Aggarwal R et. al.

Apr 8th, 2017 - To develop response criteria for juvenile dermatomyositis (DM). We analysed the performance of 312 definitions that used core set measures from either the International Myositis Assessment and Clinical Studies Group (IMACS) or the Paediatric Rheum...

2016 American College of Rheumatology/European League Against Rheumatism criteria for m...
Annals of the Rheumatic Diseases; Aggarwal R, Rider LG et. al.

Apr 8th, 2017 - To develop response criteria for adult dermatomyositis (DM) and polymyositis (PM). Expert surveys, logistic regression, and conjoint analysis were used to develop 287 definitions using core set measures. Myositis experts rated greater improvement ...

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Drugs  203 results see all →

Clinicaltrials.gov  30 results

A Study In Adults With Moderate To Severe Dermatomyositis

Jun 16th, 2022 - A Study looking at Investigational drug and Placebo administered to adult Patients with moderate to severe Dermatomyositis

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

Jun 8th, 2022 - PRIMARY OBJECTIVE: I. To assess the overall safety, including the incidence of dose-limiting toxicity (DLT), and other toxicities associated with the use of the anti-programmed death 1 (PD-1) antibody nivolumab in patients with varying severity of...

Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis

Jun 3rd, 2022 - The study will be conducted in 2 parts: Part A (Phase 2) and Part B (Phase 3). There will be 3 periods in both Part A and Part B of this study: Screening Period, Randomized Controlled Period, and Open-Label Extension Period.

Chronic Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies

Jun 3rd, 2022 - Systemic autoimmune myopathies are rheumatic diseases that affect the striatum skeletal muscles. Depending on the clinical, pathophysiological and laboratory characteristics, they may be subdivided into polymyositis, dermatomyositis, antissintetas...

Gastric Mucosal Changes in Patients With Dermatomyositis

Jun 2nd, 2022 - There are a large number of reports in the literature that patients with dermatomyositis often have various malignant tumors, and reports of gastric cancer are not rare. At present, the widely recognized gastric cancer occurrence patterns are: nor...

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News  208 results

Lenabasum Improved Skin Symptoms in Dermatomyositis, but Future Is Uncertain

May 13th, 2022 - An investigative synthetic cannabinoid receptor type 2 (CB2) agonist, lenabasum, was associated with greater improvements than placebo in patients with skin-predominant dermatomyositis — some of it statistically significant — in a phase 2 double-b...

Unique Dermatology Residency Track Focuses on Rural Placement of Graduates

May 11th, 2022 - BOSTON – As a former active-duty cavalry officer in the U.S. Army who served a 15-month tour in Iraq in 2003, Adam C. Byrd, MD, isn't easily rattled. On any given day, as the only dermatologist in his hometown of Louisville, Miss., which has a pop...

Fast Five Quiz: Progressive Fibrosing Interstitial Lung Disease

Apr 12th, 2022 - Interstitial lung diseases (ILDs) encompass a large and varied group of parenchymal lung disorders, including diseases of unknown cause, which are known as idiopathic interstitial pneumonias, as well as those associated with other diseases or envi...

Bilateral palmar rash
MDedge Family Medicine;

Apr 6th, 2022 - A biopsy was performed and the pathology report showed ectatic, thin-walled vessels consistent with telangiectasias. There were no other inflammatory, infectious, or malignant changes.

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Patient Education  9 results see all →