ALLMedicine™ Epidermolysis Bullosa Center

Oct 22nd, 2021 - Read-through for nonsense mutations in type XVII collagen deficient junctional epidermolysis bullosa.|2021|Has C,Sayar SB,Zheng S,Chacón-Solano E,Condrat I,|

Oct 12th, 2021 - Accurate diagnosis of epidermolysis bullosa (EB) has significant implications for prognosis, management, and genetic counseling. To describe diagnostic testing patterns and assess diagnostic concordance of transmission electron microscopy (TEM), i...

Oct 7th, 2021 - Diagnostic Considerations The clinical, histologic, and immunohistochemical features of bullous systemic lupus erythematosus can resemble epidermolysis bullosa acquisita (the inflammatory form more often than the classic mechanobullous form), derm...

Oct 5th, 2021 - Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin blistering disease associated with progressive multi-organ fibrosis. RDEB is caused by biallelic mutations in COL7A1 encoding the extracellular matrix protein collagen VII (C7), w...

Oct 2nd, 2021 - Epidermolysis bullosa (EB) is characterized by skin fragility with blister formation occurring spontaneously or following minor trauma such as gentle pressure or friction. Current physiotherapy practice is based on anecdotal care, clinical experti...

Jan 22nd, 2015 - Inherited epidermolysis bullosa (EB) comprises a group of rare disorders that have multi-system effects and patients present with a number of both acute and chronic pain care needs. Effects on quality of life are substantial. Pain and itching are ...

Sep 20th, 2021 - DEFI-RDEB is a multi-center, intra-patient randomized, controlled, open-label, Phase 3 study of FCX-007 for the treatment of persistent non-healing and recurrent RDEB wounds in approximately 24 subjects. Each subject will serve as his/her own cont...

Sep 13th, 2021 - Four subjects are planned for the Phase II portion of this study: 2 adults and 2 subjects age 5 and older. Subjects are enrolled upon obtaining consent and meeting entry criteria. Three wounds are selected per subject; two will receive bercolagene...

Sep 5th, 2021 - Epidermolysis bullosa is a group of rare genetic diseases characterized by the occurrence of blisters and erosions due to skin fragility. There are 4 different subgroups, based on the location of the skin cleavage area. The most frequent subgroup ...

Sep 5th, 2021 - Determination of sexual development in children with various types of inherited epidermolysis bullosa using clinical, laboratory and instrumental methods for diagnosing the condition. Phenotyping of patients with inherited epidermolysis bullosa, t...

May 24th, 2021 - Few but persistent wounds often remain even after successful hematopoietic cell transplantation for systemic genodermatosis epidermolysis bullosa (EB). The investigators propose local wound therapy using epidermal skin grafting from the same donor...

Jul 7th, 2021 - The Diagnosis: Dowling-Degos Disease Histopathology demonstrated elongation of the epidermal rete ridges with increased basal pigmentation, suprapapillary epithelial thinning, dermal melanophages, and a mild lymphocytic infiltrate (Figure). Given.

Jan 26th, 2021 - The Diagnosis: Epidermolysis Bullosa Acquisita The diagnosis of epidermolysis bullosa acquisita (EBA) was made based on the clinical and pathologic findings. A blistering disorder that resolves with milia is characteristic of EBA.

Jan 6th, 2021 - Wound cultures from patients with the rare disease epidermolysis bullosa (EB) were most frequently positive for Staphylococcus aureus (SA), Pseudomonas aeruginosa (PA), and Streptococcus pyogenes (GAS) — and antibiotic resistance was common — in a...

Nov 2nd, 2020 - A gel derived from birch bark is the first topical medication ever tested in the treatment of epidermolysis bullosa (EB) to heal wounds faster than placebo. The results come from the largest double-blind, randomized trial performed in this patient...

Mar 27th, 2020 - One of the aphorisms in dermatology, according to Lawrence Eichenfield, MD, is that prescription pads have become suggestion pads. Patients face consistent head-on refusals from insurers to fill off-label prescriptions for the many dermatologic co...