ALLMedicine™ Hereditary Pancreatitis Center

May 20th, 2022 - The overall purpose of this research project is to establish a registry of patients with pancreatic diseases. Patients included in the registry may include those with: pancreatic cancer, precancerous lesions of the pancreas such as intraductal pap...

Mar 26th, 2022 - Hereditary pancreatitis (HP) encompasses two distinct disease groups: the first manifests as congenital exocrine pancreatic insufficiency (EPI), and the second includes hereditary forms of pancreatitis. EPI represents the ultimate expression of gl...

Mar 16th, 2022 - Wild-Type Human PRSS2 and PRSS1R122H Cooperatively Initiate Spontaneous Hereditary Pancreatitis in Transgenic Mice.|2022|Wang J,Wan J,Wang L,Pandol SJ,Bi Y,|

Feb 11th, 2022 - Observational studies have suggested an increased risk of pancreatic ductal adenocarcinoma (PDAC) in patients with acute and chronic pancreatitis. We conducted a systematic review and meta-analysis to evaluate the magnitude of this association and...

Jan 23rd, 2022 - T7K24R mice carry mutation p.K24R in mouse cationic trypsinogen (isoform T7), which is analogous to the human hereditary pancreatitis-associated mutation p.K23R. The mutation renders trypsinogen more prone to autoactivation. We recently reported t...

May 20th, 2022 - The overall purpose of this research project is to establish a registry of patients with pancreatic diseases. Patients included in the registry may include those with: pancreatic cancer, precancerous lesions of the pancreas such as intraductal pap...

Sep 19th, 2019 - Pancreatic cancer is a devastating disease with a dismal prognosis. One of the ways to improve survival might be early detection. Within years, many predisposing diseases or genetic conditions have been identified, thus screening/surveillance have...

Jan 29th, 2009 - INTRODUCTION Chronic pancreatitis (CP) is a progressive inflammatory disease of the pancreas accompanied by abdominal pain and in late stages, by exocrine and endocrine insufficiency. The etiology of CP include alcohol abuse, hereditary, ductal ob...

Jun 1st, 2021 - Key clinical point: Over half of the patients with childhood-onset hereditary pancreatitis developed exocrine pancreatic insufficiency (EPI). EPI development preceded loss of endocrine function in this rare patient population.

Dec 5th, 2020 - Abstract Pancreatic cancer will be second only to lung cancer as the most common cause of death from cancer in US by 2030. Most patients are diagnosed with unresectable disease. In this setting, novel combinations of cytotoxics such as FOLFIR...

Dec 5th, 2020 - Rebecca M. Minter, MD Alvin Baldwin Jr Chair in Surgery Professor, Surgery UT Southwestern Medical Center Dallas, Texas Nisa Kubiliun, MD Director, Endoscopic Services Assistant Professor, Department of Internal Medicine UT Southw...

Jun 10th, 2020 - Individuals at high risk for pancreatic cancer should at least be considered for screening for the disease, states a new clinical practice update from the American Gastroenterological Association that further defines what constitutes high risk for.

Apr 30th, 2019 - Q2. Correct Answer: B Rationale: The PRSS1 mutation has been shown to be the causative genetic factor in hereditary pancreatitis.