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About 2,735 results

ALLMedicine™ Lichen Planus Center

Research & Reviews  949 results

Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)
https://clinicaltrials.gov/ct2/show/NCT03395340

Oct 15th, 2021 - Background: Chronic graft-versus-host disease (cGVHD) develops in approximately half of individuals who undergo allogeneic hematopoietic cell transplant (HCT) and is the leading cause of non-relapse mortality. There are no skin-targeted therapies ...

Characterization and function of circulating mucosal associated invariant T cells and γ...
https://doi.org/10.1111/jop.13250
Journal of Oral Pathology & Medicine : Official Publicati... Yang JY, Wang F et. al.

Oct 13th, 2021 - Oral lichen planus (OLP) is a T-cell mediated chronic inflammatory disease with uncertain etiology. Mucosal associated invariant T (MAIT) cells and γδT cells are unconventional, innate-like T cells with immunoregulatory capacity. This study was ai...

Detection of Epstein-Barr virus encoded small RNA genes in oral squamous cell carcinoma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495909
BMC Oral Health; Zebardast A, Yahyapour Y et. al.

Oct 8th, 2021 - Epstein-Barr Virus (EBV) is a human oncogenic virus that can lead to cancer in lymphoid and epithelial cells and is one of the hypothesized causes of oral cavity lesions including oral squamous cell carcinoma (OSCC), but the etiological associatio...

Assessment of Clinical and Laboratory Use of the Cutaneous Direct Immunofluorescence As...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495595
JAMA Dermatology; Reimann JDR, Moynihan SP et. al.

Oct 7th, 2021 - Dermatologists submit direct immunofluorescence (DIF) biopsies on a daily basis, using an assay detecting immunoreactant deposition with a panel that has traditionally comprised immunoglobulin (Ig) G, IgA, IgM, C3, and fibrin, with or without albu...

Topical opioid use in dermatologic disease: A systematic review.
https://doi.org/10.1111/dth.15150
Dermatologic Therapy; Gutierrez Y, Pourali SP et. al.

Oct 5th, 2021 - Topical opioid formulations offer a potential solution to manage pain and decrease the use of systemic opioids. Synthesis of use and efficacy of topical opioids in dermatological conditions has not been well characterized. We conducted a systemati...

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Guidelines  2 results

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin Summary, Numb...
https://doi.org/10.1097/AOG.0000000000003945
Obstetrics and Gynecology;

Jun 27th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin, Number 224.
https://doi.org/10.1097/AOG.0000000000003944
Obstetrics and Gynecology;

Jun 27th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

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Drugs  44 results see all →

Clinicaltrials.gov  14 results

Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)
https://clinicaltrials.gov/ct2/show/NCT03395340

Oct 15th, 2021 - Background: Chronic graft-versus-host disease (cGVHD) develops in approximately half of individuals who undergo allogeneic hematopoietic cell transplant (HCT) and is the leading cause of non-relapse mortality. There are no skin-targeted therapies ...

Ixekizumab in Adult Patients With Lichen Planus and Lichen Planopilaris
https://clinicaltrials.gov/ct2/show/NCT05030415

Sep 1st, 2021 - A proof of concept, non-randomized, one center study to explore the safety and efficacy of 16 weeks of treatment with ixekizumab in adult patients with lichen planus. The total study period will consist of 24 weeks including a 2 week screening/was...

Dexamethasone Solution for the Treatment of Oral Lichen Planus
https://clinicaltrials.gov/ct2/show/NCT02850601

Jun 14th, 2021 - Potentially eligible subjects will be screened by one of the investigators by asking patients to rate their worst oral pain or pain score (0-10) over the previous week (see Appendix). Those answering with at least a score of "7" (1/10) and that me...

Laser Therapy in Women With Lichenoid Disorders
https://clinicaltrials.gov/ct2/show/NCT04697563

Jan 11th, 2021 - Background: Lichenoid Disorders (LD) include VLS (Vulvar lichen sclerosus) and LP (Lichen planus). VLS and LP are chronic skin diseases that usually affect the anogenital region. Both can cause vulvar itching, burning and pain and can lead to urin...

Effect of Oral Zinc Supplementation as an Adjuvant to Topical Corticosteroid in Oral Lichen Planus Patients
https://clinicaltrials.gov/ct2/show/NCT04278599

Jul 21st, 2020 - Lichen planus is a chronic muco-cutaneous disorder of the stratified squamous epithelium that affects the oral and genital mucous membrane, skin, hair, nails and scalp.OLP is the mucosal counterpart of cutaneous lichen planus.The disease was first...

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News  80 results

Review Eyes Nail Unit Toxicities Secondary to Targeted Cancer Therapy
https://www.medscape.com/viewarticle/957155

Aug 24th, 2021 - Paronychia and periungual pyogenic granulomas are the most common nail unit toxicities related to targeted cancer therapies and immunotherapies, while damage to other nail unit anatomic areas can be wide-ranging. Those are key findings from an evi...

Fast Five Quiz: Are You Prepared to Confront Hepatitis C?
https://reference.medscape.com/viewarticle/833773

Jun 4th, 2021 - Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It is a major public health problem. Infection with HCV can lead to both acute and chronic hepatitis, varying in severity from a mild illness of short duration to a serious, lif...

Asymptomatic hyperpigmented skin changes
https://www.mdedge.com/familymedicine/article/241010/dermatology/asymptomatic-hyperpigmented-skin-changes
MDedge Family Medicine;

Jun 3rd, 2021 - The intertriginous findings, along with results from a punch biopsy showing resolving lichenoid inflammation with post-inflammatory pigmentary alteration, indicated a diagnosis of lichen planus pigmentosus inversus (LPPI). Insidious onset of usual.

Isolated Perianal Erosive Lichen Planus: A Diagnostic Challenge
https://www.mdedge.com/dermatology/article/238301/dermatopathology/isolated-perianal-erosive-lichen-planus-diagnostic
Marely Santiago, MD, Oscar Nevarez, MD et. al.

Apr 7th, 2021 - To the Editor: Erosive lichen planus (LP) often is painful, debilitating, and resistant to topical therapy making it both a diagnostic and therapeutic challenge. We report the case of an elderly woman with isolated perianal erosive LP, a rare clin.

Tiny papules on trunk and genitals
https://www.mdedge.com/familymedicine/article/231650/dermatology/tiny-papules-trunk-and-genitals
MDedge Family Medicine;

Nov 11th, 2020 - The miniscule papules arising suddenly on the trunk and genitals with linear arrays and clusters are clinically consistent with lichen nitidus, an uncommon eruption without a clear etiology. Presentations may be focal or widespread and range from.

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Patient Education  5 results see all →