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About 3,708 results

ALLMedicine™ Stevens-Johnson Syndrome Center

Research & Reviews  840 results

Microbial Keratitis in Patients With Stevens-Johnson Syndrome and Toxic Epidermal Necro...
https://doi.org/10.1097/ICO.0000000000003063
Cornea Tsai TY, Adiyabazar D et. al.

May 20th, 2022 - The purpose of this study was to analyze the clinical features, causative microorganisms, antibiotic susceptibility, and treatment outcomes in culture-proven microbial keratitis (MK) in patients with Stevens-Johnson syndrome/toxic epidermal necrol...

Human Oral Mucosal Fibroblasts from Limbal Stem Cell Deficient Patients as an Autologou...
https://doi.org/10.1080/02713683.2022.2071944
Current Eye Research; O'Callaghan AR, Shortt AJ et. al.

May 17th, 2022 - To investigate if human oral mucosal fibroblasts (HOMF) from patients with limbal stem cell deficiency (LSCD) can be used as an autologous feeder layer to support the culture of epithelial cells for potential clinical use. HOMF were isolated from ...

Genetic markers for methazolamide-induced Stevens-Johnson syndrome and toxic epidermal ...
https://doi.org/10.1111/jdv.18158
Journal of the European Academy of Dermatology and Venere... Huang PW, Chu CY

May 11th, 2022 - Genetic markers for methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis.|2022|Huang PW,Chu CY,|

Photodistributed Toxic Epidermal Necrolysis: Case Report and Review of Current Literature.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069340
JAMA Dermatology; Gaghan LJ, Coates MM et. al.

May 5th, 2022 - Cases of photodistributed Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have been infrequently reported since the first documented case in 1989. This emerging clinical entity and its underlying mechanism have yet to be fully ...

Drug Reactions Sampling (COLLECTIONTOXIDERMIES)
https://clinicaltrials.gov/ct2/show/NCT03659227

May 3rd, 2022 - Intro: Dermatology department of Henri Mondor Hospital (Creteil, France), is a reference center for toxic bullous diseases and severe cutaneous drug reactions (Stevens-Johnson syndrome (SJS), Lyell syndrome (toxic epidermal necrolysis (TEN)), gene...

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Guidelines  5 results

Society of Dermatology Hospitalists supportive care guidelines for the management of St...
https://doi.org/10.1016/j.jaad.2020.02.066
Journal of the American Academy of Dermatology; Seminario-Vidal L, Kroshinsky D et. al.

Mar 11th, 2020 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by...

Outpatient management and follow-up recommendations for adverse drug reactions: guideli...
https://www.ncbi.nlm.nih.gov/pubmed/31233575
Cutis Khanna R, Vaudreuil A et. al.

Jun 25th, 2019 - Acute generalized exanthematous pustulosis (AGEP), drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are types of adverse drug reactions (ADRs), each with their ...

British Association of Dermatologists' guidelines for the management of Stevens-Johnson...
https://doi.org/10.1111/bjd.17841
The British Journal of Dermatology; McPherson T, Exton LS et. al.

Mar 5th, 2019 - British Association of Dermatologists' guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018.|2019|McPherson T,Exton LS,Biswas S,Creamer D,Dziewulski P,|methods,standards,standards,...

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847474
Clinical Pharmacology and Therapeutics; Phillips EJ, Sukasem C et. al.

Feb 3rd, 2018 - The variant allele HLA-B*15:02 is strongly associated with greater risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine. The variant allele HLA-A*31:01 is associated wi...

Clinical Pharmacogenetics Implementation Consortium guidelines for HLA-B genotype and c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748365
Clinical Pharmacology and Therapeutics; Leckband SG, Kelsoe JR et. al.

May 23rd, 2013 - Human leukocyte antigen B (HLA-B) is a gene that encodes a cell surface protein involved in presenting antigens to the immune system. The variant allele HLA-B*15:02 is associated with an increased risk of Stevens-Johnson syndrome (SJS) and toxic e...

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Drugs  523 results see all →

Clinicaltrials.gov  12 results

Drug Reactions Sampling (COLLECTIONTOXIDERMIES)
https://clinicaltrials.gov/ct2/show/NCT03659227

May 3rd, 2022 - Intro: Dermatology department of Henri Mondor Hospital (Creteil, France), is a reference center for toxic bullous diseases and severe cutaneous drug reactions (Stevens-Johnson syndrome (SJS), Lyell syndrome (toxic epidermal necrolysis (TEN)), gene...

Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism)
https://clinicaltrials.gov/ct2/show/NCT05320653

Apr 18th, 2022 - There are yet no description of the metabolic characteristics of patients admitted for Toxic epidermal necrolysis (TEN) or Stevens-Johnson Syndrome (SJS) which are a rare condition, often assimilated to major burns in terms of metabolic requiremen...

NATIENS: Optimal Management and Mechanisms of SJS/TEN
https://clinicaltrials.gov/ct2/show/NCT02987257

Apr 15th, 2022 - Background and Scientific Rationale Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe, life-threatening immunologically mediated adverse drug reactions representing the same disease across a spectrum of severity that ...

Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
https://clinicaltrials.gov/ct2/show/NCT05145959

Dec 6th, 2021 - The investigators' aim is to study the effects of mechanical expression of meibomian glands on eyelid disease, ocular surface health in the subacute phase of SJS/TEN. The primary outcome is to use meibomian gland imaging to assess the health and c...

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
https://clinicaltrials.gov/ct2/show/NCT03041883

Jul 30th, 2021 - The Boston type 1 keratoprosthesis (KPro) is an artificial cornea that restores the clarity of the visual axis. It is indicated in patients for whom conventional corneal transplantation offers a very low probability of success. Several innovations...

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News  99 results

Age, Skin Cancer Risks for ICI-Induced Bullous Pemphigoid
https://www.medscape.com/viewarticle/972516

Apr 21st, 2022 - Bullous pemphigoid, an immune-mediated condition chacterized by large, fluid-filled blisters on the skin, is a rare but serious complication of cancer therapy with immune checkpoint inhibitors (ICIs) that may result in treatment interruption or ce...

Adverse Skin Effects of Cancer Immunotherapy Reviewed
https://www.medscape.com/viewarticle/970581

Mar 18th, 2022 - Immune checkpoint inhibitors (ICIs) have unquestionably revolutionized the care of patients with malignant melanoma, non-small cell lung cancer, and other types of cancer. But about 40% of patients with cancer treated with ICIs will experience imm...

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap in a Pregnant Patient
https://www.mdedge.com/dermatology/article/250034/mixed-topics/stevens-johnson-syndrome/toxic-epidermal-necrolysis-overlap
Samantha Shwe, BS, Allison S. Dobry, MD et. al.

Dec 17th, 2021 - To the Editor: A 34-year-old pregnant woman at 5 weeks’ gestation was transferred to dermatology from an outside hospital with a full-body rash. Three days after noting a fever and generalized body aches, she developed a painful rash on the legs t.

Bullae on elderly woman’s toes
https://www.mdedge.com/familymedicine/article/249354/dermatology/bullae-elderly-womans-toes
MDedge Family Medicine;

Dec 2nd, 2021 - A biopsy was performed and sent for immunofluorescence; the results were negative. This, along with the patient’s history of diabetes, led us to the diagnosis of bullosis diabeticorum (BD).

Expert Highlights Management of Immune-Related Toxicities With NSCLC Treatment
https://www.onclive.com/view/expert-highlights-management-of-immunerelated-toxicities-with-nsclc-treatment

Oct 6th, 2021 - Mohamed K. Mohamed, MD Pembrolizumab (Keytruda) has emerged as a reliable frontline treatment option for patients with metastatic non—small cell lung cancer (NSCLC), but thoracic oncologists need to be aware of potentially severe immune-related a...

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Patient Education  4 results see all →