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About 9,988 results

ALLMedicine™ Amyloidosis Center

Research & Reviews  3,658 results

Editorial for "Non-enhanced Chemical Exchange Saturation Transfer Cardiac Magnetic Reso...
https://doi.org/10.1002/jmri.27857
Journal of Magnetic Resonance Imaging : JMRI; Winter PM

Jul 23rd, 2021 - Editorial for "Non-enhanced Chemical Exchange Saturation Transfer Cardiac Magnetic Resonance Imaging in Patients With Amyloid Light Chain Amyloidosis".|2021|Winter PM,|

Primary Localized Cutaneous Amyloidosis of Keratinocyte Origin: An Update with Emphasis...
https://doi.org/10.1007/s40257-021-00620-9
American Journal of Clinical Dermatology; Hamie L, Haddad I et. al.

Jul 21st, 2021 - Amyloid is a protein derived from at least 20 different substances. Once misfolded, it results in a group of cutaneous and systemic conditions. Primary localized cutaneous amyloidosis of keratinocyte origin is a very common subtype that can manife...

External validation of the increased wall thickness score for the diagnosis of cardiac ...
https://doi.org/10.1016/j.ijcard.2021.07.035
International Journal of Cardiology; Monda E, Palmiero G et. al.

Jul 21st, 2021 - This study aimed to validate the increased wall thickness (IWT) score, a multiparametric echocardiographic score to facilitate diagnosis of cardiac amyloidosis (CA), in an independent population of patients with increased LV wall thickness suspici...

The value of nerve biopsy in transthyretin amyloidosis with competing comorbidities.
https://doi.org/10.1017/cjn.2021.175
The Canadian Journal of Neurological Sciences. Le Journal... Mak G, Chum M et. al.

Jul 19th, 2021 - The value of nerve biopsy in transthyretin amyloidosis with competing comorbidities.|2021|Mak G,Chum M,Lu JQ,|

Prognostic Role of Cardiopulmonary Exercise Testing in Wild Type Transthyretin Amyloid ...
https://doi.org/10.1016/j.cardfail.2021.06.022
Journal of Cardiac Failure; Dalia T, Acharya P et. al.

Jul 19th, 2021 - Prognostic value of cardiopulmonary exercise test (CPET) in wild type transthyretin cardiac amyloidosis (wtATTR) patients treated with Tafamidis is unknown. This is a retrospective study of wtATTR patients who underwent baseline CPET and were trea...

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Guidelines  7 results

Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement...
https://doi.org/10.1016/j.cjca.2019.12.034
The Canadian Journal of Cardiology; Fine NM, Davis MK et. al.

Mar 8th, 2020 - Cardiac amyloidosis is an under-recognized and potentially fatal cause of heart failure and other cardiovascular manifestations. It is caused by deposition of misfolded precursor proteins as fibrillary amyloid deposits in cardiac tissues. The two ...

Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement ...
https://doi.org/10.1016/j.cjca.2019.12.025
The Canadian Journal of Cardiology; Chih S, McDonald M et. al.

Mar 8th, 2020 - Significant practice-changing developments have occurred in the care of heart transplantation candidates and recipients over the past decade. This Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement provides evid...

CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgita...
https://doi.org/10.1016/j.cjca.2019.11.036
The Canadian Journal of Cardiology; O'Meara E, McDonald M et. al.

Feb 9th, 2020 - In this update, we focus on selected topics of high clinical relevance for health care providers who treat patients with heart failure (HF), on the basis of clinical trials published after 2017. Our objective was to review the evidence, and provid...

2019 HRS expert consensus statement on evaluation, risk stratification, and management ...
https://doi.org/10.1016/j.hrthm.2019.05.007
Heart Rhythm; Towbin JA, McKenna WJ et. al.

May 12th, 2019 - Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a broad spectrum of genetic, systemic, infectious, and inflammatory disorders....

Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2017.0023
Journal of the National Comprehensive Cancer Network : JN... Kumar SK, Callander NS et. al.

Feb 11th, 2017 - Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-r...

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Drugs  11 results see all →

Clinicaltrials.gov  106 results

The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)
https://clinicaltrials.gov/ct2/show/NCT02510261

May 4th, 2020 - The purpose of this study is to evaluate the safety and efficacy of long-term dosing with ALN-TTR02 (patisiran) in patients with transthyretin (TTR) mediated amyloidosis (ATTR).

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid L...
https://clinicaltrials.gov/ct2/show/NCT03201965

Apr 30th, 2020 - Participant involved in study for approx. 8 years duration includes Screening Phase (complete clinical evaluation will be done), Treatment Phase (monitoring of adverse events (AEs), laboratory abnormalities and clinical response), Post-Treatment O...

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics
https://clinicaltrials.gov/ct2/show/NCT00001373

Apr 29th, 2020 - The purpose of this protocol is to study the genetics and pathophysiology of familial Mediterranean fever (FMF) and other related diseases. FMF is a recessively inherited condition characterized by episodes of fever and serositis or synovitis; som...

Epidemiological Analysis for the Hereditary Transthytetin-related Amyloidosis (hATTR)
https://clinicaltrials.gov/ct2/show/NCT03237494

Apr 19th, 2020 - Hereditary TransThyRetin Amyloidosis (hATTR) is a slowly progressive condition, that is transmitted as an autosomal dominant trait and is characterized by abnormal extracellular deposits of fibrillar, misfolded proteins (amyloid fibrils) in the bo...

Cardiac Uptake of 18F Florbetapir in Patients Undergoing Chemotherapy
https://clinicaltrials.gov/ct2/show/NCT03333551

Apr 9th, 2020 - Current research involving [18F]-florbetapir in relationship to cardiac amyloid has taken advantage of the ability of the radiopharmaceutical to bind specifically to amyloid fibrils. It has previously been established that the degree of radiotrace...

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News  201 results

Add-On Daratumumab Triples Complete Response Rate in AL Amyloidosis
https://www.medscape.com/viewarticle/954043

Jul 1st, 2021 - NEW YORK (Reuters Health) - Adding daratumumab to conventional therapy with cyclophosphamide, bortezomib and dexamethasone (CyBorD) nearly triples the rate of complete hematologic response in people with newly diagnosed systemic immunoglobulin lig...

Fast Five Quiz: Treatment of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://reference.medscape.com/viewarticle/912776?src=sapfe

May 23rd, 2021 - Hereditary (familial) amyloid transthyretin-related (hATTR) amyloidosis is a rare, severely debilitating, and often fatal disorder caused by a mutation in the gene encoding transthyretin (TTR). It results in abnormal amyloid protein buildup in mul...

Fast Five Quiz: Presentation and Diagnosis of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://reference.medscape.com/viewarticle/912774

May 23rd, 2021 - Transthyretin (TTR) is a transport protein for thyroxine and retinol. It can also be associated with the formation and deposition of amyloid fibril proteins within organs and tissues, especially the nervous system and cardiac tissue, leading to or...

Fast Five Quiz: Treatment of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://reference.medscape.com/viewarticle/912776

May 23rd, 2021 - Hereditary (familial) amyloid transthyretin-related (hATTR) amyloidosis is a rare, severely debilitating, and often fatal disorder caused by a mutation in the gene encoding transthyretin (TTR). It results in abnormal amyloid protein buildup in mul...

Fast Five Quiz: Presentation and Diagnosis of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://www.medscape.com/viewarticle/912774

May 23rd, 2021 - Transthyretin (TTR) is a transport protein for thyroxine and retinol. It can also be associated with the formation and deposition of amyloid fibril proteins within organs and tissues, especially the nervous system and cardiac tissue, leading to or...

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Patient Education  12 results see all →