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About 9,423 results

ALLMedicine™ Amyloidosis Center

Research & Reviews  3,552 results

Clinical and prognostic implications of capillary density in patients with cardiac ligh...
https://doi.org/10.1002/ehf2.13604
ESC Heart Failure; Kim D, Choi JO et. al.

Sep 17th, 2021 - Cardiac involvement is crucial factor determining outcomes of light chain (AL) amyloidosis. This study evaluated whether capillary density (CD) quantified from endomyocardial biopsy is associated with structural and functional parameters of amyloi...

Dexamethasone is associated with early deaths in light chain amyloidosis patients with ...
https://doi.org/10.1371/journal.pone.0257189
PloS One; Bézard M, Oghina S et. al.

Sep 16th, 2021 - Cardiac light chain amyloidosis (AL-CA) patients often die within three months of starting chemotherapy. Chemotherapy for non-immunoglobulin M gammopathy with AL-CA frequently includes bortezomib (Bor), cyclophosphamide (Cy), and dexamethasone (D)...

Primary Localized Cutaneous Amyloidosis: A Retrospective Study of an Uncommon Skin Dise...
https://doi.org/10.1159/000518948
Dermatology (Basel, Switzerland); Guillet C, Steinmann S et. al.

Sep 16th, 2021 - Primary localized cutaneous amyloidosis (PLCA) is defined by the deposition of amyloid protein in the skin without systemic involvement. There are four subtypes of PLCA: lichen amyloidosis (LA), macular amyloidosis (MA), biphasic amyloidosis (BA),...

The genetics of cardiac amyloidosis.
https://doi.org/10.1007/s10741-021-10164-z 10.1182/blood-2009-06-223792 10.3109/13506120309041738 10.1007/s10157-011-0483-4 10.1186/s13023-020-1300-5 10.1053/j.ajkd.2018.10.016 10.1056/NEJMc1917321 10.1093/ckj/sfv087 10.1093/nar/gkx1153 10.1038/s41467-019-08609-z 10.1161/CIRCULATIONAHA.111.078915 10.1016/j.jacc.2016.03.596 10.1001/archneur.58.11.1914 10.1161/CIRCHEARTFAILURE.115.002558 10.3109/13506129.2015.1019610 10.1056/NEJMoa1404852 10.1016/j.ahj.2010.02.006 10.1007/s004390050199 10.1001/jamacardio.2018.2093 10.1161/CIRCHEARTFAILURE.119.006075 10.1016/j.jacc.2016.09.987 10.1001/jama.2019.17935 10.1016/j.amjcard.2011.03.069 10.1002/ejhf.1742 10.1016/j.jacc.2019.04.054 10.1016/j.jacc.2018.07.092 10.1093/eurheartj/ehr383 10.1136/jnnp.59.1.45 10.1002/art.1780300210 10.1002/mus.880080902 10.3121/cmr.2008.794 10.3109/13506120209072442 10.1016/s0387-7604(84)80061-3 10.1073/pnas.1121005109 10.1186/s13023-017-0726-x 10.1136/jmg.31.4.293 10.1080/13506120802193720 10.1002/ajmg.1320600606 10.1212/WNL.0000000000006543 10.1080/13506120600876849 10.1097/WCO.0000000000000288 10.1136/jnnp-2013-305383 10.1212/wnl.55.3.451-a 10.1080/13506129.2020.1789580 10.1007/s004390050991 10.1136/jmg.35.1.23 10.1111/j.1399-0004.2008.01097.x 10.1186/1750-1172-10-S1-O4 10.1161/CIRCULATIONAHA.111.040071 10.1097/HCO.0000000000000276 10.1111/j.1365-2796.2004.01399.x 10.1186/s13148-020-00967-6 10.1161/CIRCGEN.120.003011 10.1038/s41374-018-0104-x 10.1038/s41467-017-02762-z 10.2147/CLEP.S253612 10.1371/journal.pone.0222886 10.1038/ncomms9570 10.1038/s41586-019-1411-0 10.1136/bmj.322.7300.1447 10.1126/science.1566067 10.3233/JAD-2010-1240 10.1136/jmg.2005.033720 10.1016/j.jmoldx.2013.08.001 10.1073/pnas.1802977115 10.1038/s41576-018-0057-3 10.2217/pme-2017-0001 10.1016/j.atg.2016.01.004 10.2147/TCRM.S219979 10.1016/j.ejim.2020.09.025
Heart Failure Reviews; Arno S, Cowger J

Sep 15th, 2021 - Heritable cardiac amyloidosis (CA) is an underrecognized cause of morbidity and mortality in the USA. It results from the accumulation of the misfolded protein transthyretin within the myocardium, resulting in amyloid transthyretin-associated card...

Fixed duration vs. prolonged duration treatment after first line therapy in patients wi...
https://doi.org/10.1080/13506129.2021.1978423
Amyloid : the International Journal of Experimental and C... Rivera Duarte A, Reece D et. al.

Sep 15th, 2021 - The main objective of treatment in systemic light chain amyloidosis (AL amyloidosis) is to achieve the best hematological response. Deeper responses are associated with better organ responses and survival. In this study, we analysed the efficacy o...

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Guidelines  7 results

Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement...
https://doi.org/10.1016/j.cjca.2019.12.034
The Canadian Journal of Cardiology; Fine NM, Davis MK et. al.

Mar 9th, 2020 - Cardiac amyloidosis is an under-recognized and potentially fatal cause of heart failure and other cardiovascular manifestations. It is caused by deposition of misfolded precursor proteins as fibrillary amyloid deposits in cardiac tissues. The two ...

Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement ...
https://doi.org/10.1016/j.cjca.2019.12.025
The Canadian Journal of Cardiology; Chih S, McDonald M et. al.

Mar 9th, 2020 - Significant practice-changing developments have occurred in the care of heart transplantation candidates and recipients over the past decade. This Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement provides evid...

CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgita...
https://doi.org/10.1016/j.cjca.2019.11.036
The Canadian Journal of Cardiology; O'Meara E, McDonald M et. al.

Feb 10th, 2020 - In this update, we focus on selected topics of high clinical relevance for health care providers who treat patients with heart failure (HF), on the basis of clinical trials published after 2017. Our objective was to review the evidence, and provid...

2019 HRS expert consensus statement on evaluation, risk stratification, and management ...
https://doi.org/10.1016/j.hrthm.2019.05.007
Heart Rhythm; Towbin JA, McKenna WJ et. al.

May 13th, 2019 - Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a broad spectrum of genetic, systemic, infectious, and inflammatory disorders....

Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2017.0023
Journal of the National Comprehensive Cancer Network : JN... Kumar SK, Callander NS et. al.

Feb 12th, 2017 - Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-r...

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Drugs  11 results see all →

News  193 results

Add-On Daratumumab Triples Complete Response Rate in AL Amyloidosis
https://www.medscape.com/viewarticle/954043

Jul 2nd, 2021 - NEW YORK (Reuters Health) - Adding daratumumab to conventional therapy with cyclophosphamide, bortezomib and dexamethasone (CyBorD) nearly triples the rate of complete hematologic response in people with newly diagnosed systemic immunoglobulin lig...

Fast Five Quiz: Treatment of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://reference.medscape.com/viewarticle/912776?src=sapfe

May 24th, 2021 - Hereditary (familial) amyloid transthyretin-related (hATTR) amyloidosis is a rare, severely debilitating, and often fatal disorder caused by a mutation in the gene encoding transthyretin (TTR). It results in abnormal amyloid protein buildup in mul...

Fast Five Quiz: Presentation and Diagnosis of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://reference.medscape.com/viewarticle/912774

May 24th, 2021 - Transthyretin (TTR) is a transport protein for thyroxine and retinol. It can also be associated with the formation and deposition of amyloid fibril proteins within organs and tissues, especially the nervous system and cardiac tissue, leading to or...

Fast Five Quiz: Treatment of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://reference.medscape.com/viewarticle/912776

May 24th, 2021 - Hereditary (familial) amyloid transthyretin-related (hATTR) amyloidosis is a rare, severely debilitating, and often fatal disorder caused by a mutation in the gene encoding transthyretin (TTR). It results in abnormal amyloid protein buildup in mul...

Fast Five Quiz: Presentation and Diagnosis of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis
https://www.medscape.com/viewarticle/912774

May 24th, 2021 - Transthyretin (TTR) is a transport protein for thyroxine and retinol. It can also be associated with the formation and deposition of amyloid fibril proteins within organs and tissues, especially the nervous system and cardiac tissue, leading to or...

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Patient Education  6 results see all →