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About 13,380 results

ALLMedicine™ Amyloidosis Center

Research & Reviews  4,644 results

State of the Art: Quantitative Cardiac MRI in Cardiac Amyloidosis.
https://doi.org/10.1002/jmri.28314
Journal of Magnetic Resonance Imaging : JMRI; Guo Y, Li X et. al.

Jul 1st, 2022 - Cardiac amyloidosis (CA) is characterized by amyloid infiltration in the myocardial extracellular space, causing heart failure. Patients with CA are currently underdiagnosed. Cardiac involvement is significantly associated with the prognosis and t...

Transcatheter aortic valve replacement in aortic stenosis and cardiac amyloidosis: a sy...
https://doi.org/10.1002/ehf2.13876
ESC Heart Failure; Cannata F, Chiarito M et. al.

Jul 1st, 2022 - Aortic stenosis (AS) and cardiac amyloidosis (CA) are typical diseases of the elderly. Up to 16% of older adults with severe AS referred to transcatheter aortic valve replacement (TAVR) have a concomitant diagnosis of CA. CA-AS population suffers ...

IgM monoclonal gammopathies of clinical significance: diagnosis and management.
https://doi.org/10.3324/haematol.2022.280953
Haematologica Khwaja J, D'Sa S et. al.

Jul 1st, 2022 - IgM monoclonal gammopathy of undetermined significance is a pre-malignant condition for Waldenstrom Macroglobulinaemia (WM) and other B-cell malignancies, defined by asymptomatic circulating IgM monoclonal protein below 30 g/l with a lymphoplasmac...

Understanding Changes in Functional Capacity After TTR Stabilization in Patients With T...
https://doi.org/10.1161/CIRCHEARTFAILURE.122.009387
Circulation. Heart Failure; Cuddy SAM

Jun 30th, 2022 - Understanding Changes in Functional Capacity After TTR Stabilization in Patients With Transthyretin Cardiac Amyloidosis.|2022|Cuddy SAM,|

Factors Associated with Increased Health-Related Quality of Life Benefits in Patients w...
https://doi.org/10.1002/mus.27668
Muscle & Nerve; Karam C, Brown D et. al.

Jun 30th, 2022 - Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) is a genetic condition associated with significant morbidity and mortality. We aimed to identify patient subgroups exhibiting the greatest health-related quality of life [HRQL] be...

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Guidelines  10 results

ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodalit...
https://doi.org/10.1161/HCI.0000000000000029
Circulation. Cardiovascular Imaging; Dorbala S, Ando Y et. al.

Jul 2nd, 2021 - ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging.|2021|Dorbala S,Ando Y,Bokhari S,Dispenzieri A,Falk RH,|diagnost...

ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodalit...
https://doi.org/10.1161/HCI.0000000000000030
Circulation. Cardiovascular Imaging; Dorbala S, Ando Y et. al.

Jul 2nd, 2021 - ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization.|2021|Dorbala S,Ando Y,Bokhari S,Dispenzieri A,Falk RH,|diagnostic...

JCS 2020 Guideline on Diagnosis and Treatment of Cardiac Amyloidosis.
https://doi.org/10.1253/circj.CJ-20-0110
Circulation Journal : Official Journal of the Japanese Ci... Kitaoka H, Izumi C et. al.

Aug 25th, 2020 - JCS 2020 Guideline on Diagnosis and Treatment of Cardiac Amyloidosis.|2020|Kitaoka H,Izumi C,Izumiya Y,Inomata T,Ueda M,|classification,diagnosis,drug therapy,epidemiology,therapeutic use,classification,diagnosis,drug therapy,epidemiology,epidemio...

Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement ...
https://doi.org/10.1016/j.cjca.2019.12.025
The Canadian Journal of Cardiology; Chih S, McDonald M et. al.

Mar 9th, 2020 - Significant practice-changing developments have occurred in the care of heart transplantation candidates and recipients over the past decade. This Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement provides evid...

Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement...
https://doi.org/10.1016/j.cjca.2019.12.034
The Canadian Journal of Cardiology; Fine NM, Davis MK et. al.

Mar 9th, 2020 - Cardiac amyloidosis is an under-recognized and potentially fatal cause of heart failure and other cardiovascular manifestations. It is caused by deposition of misfolded precursor proteins as fibrillary amyloid deposits in cardiac tissues. The two ...

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Drugs  11 results see all →

Clinicaltrials.gov  337 results

Characterization of Diseases With Salivary Gland Involvement
https://clinicaltrials.gov/ct2/show/NCT02327884

Jun 24th, 2022 - This protocol is intended to allow disease-specific investigations in subjects with presentations of diseases with salivary gland involvement and will enable the collection of data, biological fluids and tissue samples from those subjects, their f...

Amyloidosis TTR Flow Reserve Evaluation
https://clinicaltrials.gov/ct2/show/NCT05103943

Jun 23rd, 2022 - Anginal symptoms and signs of ischemia have been reported in some patients with cardiac amyloidosis (TTR) without obstructive epicardial coronary artery disease (CAD). It was found that coronary microvascular dysfunction was highly prevalent in su...

Mixed Chimeric Transplantation for Primary Amyloidosis
https://clinicaltrials.gov/ct2/show/NCT00186095

Jun 23rd, 2022 - To evaluate the role of nonmyeloablative allogeneic transplantation in Amyloidosis.

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid L...
https://clinicaltrials.gov/ct2/show/NCT03201965

Jun 21st, 2022 - Participant involved in study for approx. 8 years duration includes Screening Phase (complete clinical evaluation will be done), Treatment Phase (monitoring of adverse events (AEs), laboratory abnormalities and clinical response), Post-Treatment O...

Intracardiac Flow Assessment in Cardiac Amyloidosis
https://clinicaltrials.gov/ct2/show/NCT05379101

Jun 21st, 2022 - The primary objective of this study is to define the intracardiac flow imaging biomarkers in cardiac amyloidosis.

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News  334 results

FDA OKs Vutrisiran for hATTR Amyloidosis With Polyneuropathy
https://www.medscape.com/viewarticle/975561

Jun 14th, 2022 - The US Food and Drug Administration (FDA) has approved vutrisiran (Amvuttra, Alnylam Pharmaceuticals) for the treatment of polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults, the company has announced. hATTR amyloido...

Rippled Macules and Papules on the Legs
https://www.mdedge.com/dermatology/article/255246/mixed-topics/rippled-macules-and-papules-legs
Kieu Oanh Nguyen, MD, Kristopher M. Peters, DO

Jun 7th, 2022 - The Diagnosis: Cutaneous Amyloidosis A punch biopsy confirmed the diagnosis of cutaneous amyloidosis, which is characterized by the deposition of amyloid proteins in the skin without systemic involvement. Subtypes of cutaneous amyloidosis include.

Tau Moderated by Menopause; CTE Risk Underestimated; When Is a Single Study Enough?
https://www.medpagetoday.com/neurology/generalneurology/98523

May 3rd, 2022 - Menopause status moderated sex differences in tau burden, with a divergence in tauopathy between the sexes apparent 20 years earlier than previously reported. (Annals of Neurology) Plasma p-tau was a less consistent marker of brain amyloidosis in ...

TTR Gene Variant Ups Risk of Heart Failure Among Black Individuals
https://www.medscape.com/viewarticle/971593

Apr 6th, 2022 - NEW YORK (Reuters Health) - The risk of heart failure is increased in Black carriers of the transthyretin (TTR) Val122Ile mutation, the genetic basis of hereditary transthyretin amyloidosis cardiomyopathy (hATTR-CM), a new study shows. "Although t...

New Tool Detects Difficult-to-Diagnose Cardiac Conditions
https://www.medscape.com/viewarticle/970458

Mar 17th, 2022 - Clinicians at the Smidt Heart Institute at Cedars-Sinai Medical Center in Los Angeles have developed a new algorithm that can effectively identify and distinguish between two cardiovascular conditions, hypertrophic cardiomyopathy and cardiac amylo...

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Patient Education  16 results see all →