CORGARD (nadolol) is available for oral administration as 20 mg, 40 mg, and 80 mg tablets.
KAPSPARGO Sprinkle is a beta1-selective adrenoceptor blocking agent indicated for the treatment of: Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.
Official HCP website for Ranexa® (ranolazine). Learn about dosing, safety and side effects, benefits, and risks.
When discontinuing chronically administered TOPROL-XL, particularly in patients with ischemic heart disease, the dosage should be gradually reduced over a ...
Journal of the American College of Cardiology;
Dec 11th, 2006 - The importance of resting heart rate (HR) as a prognostic factor and potential therapeutic target is not yet generally accepted. Recent large epidemiologic studies have confirmed earlier studies that showed resting HR to be an independent predictor of cardiovascular and all-cause mortality in men and women with and without diagnosed cardiovascular disease. Clinical trial data suggest that HR re...
Aug 31st, 2019 - Oxygen supplementation has been a cornerstone in the initial treatment of individuals with acute coronary syndrome. While consensus for oxygen supplementation exists for patients with hypoxia, oxygen supplementation has also been routinely used in those presenting with acute myocardial infarction (MI) with normal oxygen saturations based on the rationale that oxygen therapy could improve oxygen...
Mar 1st, 2019 - Nitroglycerin is a vasodilatory drug that is used primarily to provide relief from anginal chest pain. Nitroglycerin has been FDA approved since 2000 and was first sold by Pfizer under the brand name Nitrostat. It is currently FDA approved for the acute relief of an attack or acute prophylaxis of angina pectoris secondary to coronary artery disease. Off-label, non-FDA approved uses include trea...
Kapspargo Sprinkle™ extended-release capsules are for the treatment of hypertension, angina pectoris, and heart failure. Learn more here.
Lancet (London, England); Tegn N, Abdelnoor M et. al.
Jan 22nd, 2016 - Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina pectoris are frequent causes of hospital admission in the elderly. However, clinical trials targeting this population are scarce, and these patients are less likely to receive treatment according to guidelines. We aimed to investigate whether this population would benefit from an early invasive strategy versus a conservative st...
Lancet (London, England); Mäkikallio T, Holm NR et. al.
Nov 4th, 2016 - Coronary artery bypass grafting (CABG) is the standard treatment for revascularisation in patients with left main coronary artery disease, but use of percutaneous coronary intervention (PCI) for this indication is increasing. We aimed to compare PCI and CABG for treatment of left main coronary artery disease. In this prospective, randomised, open-label, non-inferiority trial, patients with left...
Journal of the American Geriatrics Society; Rothschild DP, Novak E et. al.
Jun 13th, 2016 - To examine the effect of statins on long-term mortality in older adults hospitalized with coronary artery disease (CAD). Retrospective analysis. University teaching hospital. Individuals aged 80 and older (mean aged 85.2, 56% female) hospitalized from January 2006 to December 2010 with acute myocardial infarction (AMI), unstable angina pectoris, or chronic CAD and discharged alive (N = 1,262). ...
Heart (British Cardiac Society); Kessous R, Shoham-Vardi I et. al.
Jan 7th, 2015 - To investigate whether severe and recurrent pre-eclampsia increase the risk for long-term maternal atherosclerotic disease. A population-based study compared the incidence of long-term atherosclerotic morbidity in a cohort of women who delivered in the years 1988-2012. The exposure variable was pre-eclampsia. Mean follow-up duration was 11.2 years. Kaplan-Meier survival curves were used to esti...
Clinical Physiology and Functional Imaging; Björkander I, Forslund L et. al.
Mar 3rd, 2009 - Heart rate variability (HRV) reflects the balance between cardiac parasympathetic and sympathetic autonomic influences. Reduced HRV has adverse prognostic implications. The time course for changes in HRV over prolonged periods of time and the influence of an acute coronary event on HRV are not well established. Heart rate variability was assessed in patients with chronic stable angina pectoris,...
Journal of the American Geriatrics Society; Baldasseroni S, Pratesi A et. al.
Aug 17th, 2016 - To assess the effect of cardiac rehabilitation (CR) and identify predictors of changes in functional capacity with CR in a consecutive series of older adults with a recent cardiac event. Observational. In-hospital CR unit. Individuals aged 75 and older referred to an outpatient CR Unit after an acute coronary event (unstable angina pectoris, acute myocardial infarction) or cardiac surgery (coro...
European Heart Journal; Tardif JC, Ponikowski P et. al.
Jan 12th, 2009 - To evaluate the anti-anginal and anti-ischaemic efficacy of the selective I(f) current inhibitor ivabradine in patients with chronic stable angina pectoris receiving beta-blocker therapy. In this double-blinded trial, 889 patients with stable angina receiving atenolol 50 mg/day were randomized to receive ivabradine 5 mg b.i.d. for 2 months, increased to 7.5 mg b.i.d. for a further 2 months, or ...
Heart (British Cardiac Society); Andréll P, Yu W et. al.
May 20th, 2010 - To assess the long-term effect of spinal cord stimulation (SCS) on angina symptoms and quality of life in patients with refractory angina pectoris defined as severe angina due to coronary artery disease resistant to conventional pharmacological therapy and/or revascularisation. During 2003-2005, all patients with refractory angina referred for SCS treatment at 10 European centres were consecuti...
American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions; Eckert S, Horstkotte D
Jan 30th, 2009 - Progress in prevention as well as drug and interventional therapy has improved the prognosis of patients with cardiovascular disorders. Many patients at risk have advanced coronary artery disease (CAD), have had multiple coronary interventions, and present with significant co-morbidity. Despite adequate risk factor modulation and often several revascularization procedures, some of these patient...
The American Journal of Cardiology; Pedone C, Elhendy A et. al.
Oct 22nd, 2008 - The clinical utility of stress testing in patients without angina pectoris after revascularization has been questioned. Dobutamine stress echocardiography (DSE) is an established technique for detection of myocardial ischemia and cardiac risk stratification. We studied the prognostic value of DSE in 393 patients without typical angina pectoris after coronary revascularization. Ischemia was incr...
The British Journal of Radiology; Ko SM, Kim YJ et. al.
Jun 23rd, 2009 - The aim of this study was to compare the measurement of left ventricular ejection fraction (LVEF) and regional wall motion using 64-slice multidetector CT (MDCT) with that using two-dimensional transthoracic echocardiography (2D-TTE) in a heterogeneous patient population. In 126 patients with angina pectoris, acute myocardial infarction, chronic myocardial infarction, atypical chest pain withou...
Proceedings of the National Academy of Sciences of the United States of America; Gravel A, Dubuc I et. al.
Jun 16th, 2015 - Inherited chromosomally integrated human herpesvirus-6 (iciHHV-6) results in the germ-line transmission of the HHV-6 genome. Every somatic cell of iciHHV-6+ individuals contains the HHV-6 genome integrated in the telomere of chromosomes. Whether having iciHHV-6 predisposes humans to diseases remains undefined. DNA from 19,597 participants between 40 and 69 years of age were analyzed by quantita...