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About 3,085 results
Nitroglycerin - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK482382/
Kim, K. et. al.

Mar 1st, 2019 - Nitroglycerin is a vasodilatory drug that is used primarily to provide relief from anginal chest pain. Nitroglycerin has been FDA approved since 2000 and was first sold by Pfizer under the brand name Nitrostat. It is currently FDA approved for the acute relief of an attack or acute prophylaxis of angina pectoris secondary to coronary artery disease. Off-label, non-FDA approved uses include trea...

Invasive versus conservative strategy in patients aged 80 years or older with non-ST-el...
https://doi.org/10.1016/S0140-6736(15)01166-6
Lancet (London, England); Tegn N, Abdelnoor M et. al.

Jan 22nd, 2016 - Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina pectoris are frequent causes of hospital admission in the elderly. However, clinical trials targeting this population are scarce, and these patients are less likely to receive treatment according to guidelines. We aimed to investigate whether this population would benefit from an early invasive strategy versus a conservative st...

Resting Heart Rate in Cardiovascular Disease
https://www.sciencedirect.com/science/article/pii/S0735109707018232
Journal of the American College of Cardiology;

Dec 11th, 2006 - The importance of resting heart rate (HR) as a prognostic factor and potential therapeutic target is not yet generally accepted. Recent large epidemiologic studies have confirmed earlier studies that showed resting HR to be an independent predictor of cardiovascular and all-cause mortality in men and women with and without diagnosed cardiovascular disease. Clinical trial data suggest that HR re...

Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment o...
https://doi.org/10.1016/S0140-6736(16)32052-9
Lancet (London, England); Mäkikallio T, Holm NR et. al.

Nov 4th, 2016 - Coronary artery bypass grafting (CABG) is the standard treatment for revascularisation in patients with left main coronary artery disease, but use of percutaneous coronary intervention (PCI) for this indication is increasing. We aimed to compare PCI and CABG for treatment of left main coronary artery disease. In this prospective, randomised, open-label, non-inferiority trial, patients with left...

Effect of Statin Therapy on Mortality in Older Adults Hospitalized with Coronary Artery...
https://doi.org/10.1111/jgs.14207
Journal of the American Geriatrics Society; Rothschild DP, Novak E et. al.

Jun 13th, 2016 - To examine the effect of statins on long-term mortality in older adults hospitalized with coronary artery disease (CAD). Retrospective analysis. University teaching hospital. Individuals aged 80 and older (mean aged 85.2, 56% female) hospitalized from January 2006 to December 2010 with acute myocardial infarction (AMI), unstable angina pectoris, or chronic CAD and discharged alive (N = 1,262). ...

Cardiac Rehabilitation in Very Old Adults: Effect of Baseline Functional Capacity on Tr...
https://doi.org/10.1111/jgs.14239
Journal of the American Geriatrics Society; Baldasseroni S, Pratesi A et. al.

Aug 17th, 2016 - To assess the effect of cardiac rehabilitation (CR) and identify predictors of changes in functional capacity with CR in a consecutive series of older adults with a recent cardiac event. Observational. In-hospital CR unit. Individuals aged 75 and older referred to an outpatient CR Unit after an acute coronary event (unstable angina pectoris, acute myocardial infarction) or cardiac surgery (coro...

Urinary Potassium Excretion and Renal and Cardiovascular Complications in Patients with...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670758
Clinical Journal of the American Society of Nephrology : CJASN; Araki S, Haneda M et. al.

Nov 13th, 2015 - We investigated the association of urinary potassium and sodium excretion with the incidence of renal failure and cardiovascular disease in patients with type 2 diabetes. A total of 623 Japanese type 2 diabetic patients with eGFR≥60 ml/min per 1.73 m(2) were enrolled in this observational follow-up study between 1996 and 2003 and followed-up until 2013. At baseline, a 24-hour urine sample was c...

Inherited chromosomally integrated human herpesvirus 6 as a predisposing risk factor fo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491735
Proceedings of the National Academy of Sciences of the United States of America; Gravel A, Dubuc I et. al.

Jun 16th, 2015 - Inherited chromosomally integrated human herpesvirus-6 (iciHHV-6) results in the germ-line transmission of the HHV-6 genome. Every somatic cell of iciHHV-6+ individuals contains the HHV-6 genome integrated in the telomere of chromosomes. Whether having iciHHV-6 predisposes humans to diseases remains undefined. DNA from 19,597 participants between 40 and 69 years of age were analyzed by quantita...

Long-term maternal atherosclerotic morbidity in women with pre-eclampsia.
https://doi.org/10.1136/heartjnl-2014-306571
Heart (British Cardiac Society); Kessous R, Shoham-Vardi I et. al.

Jan 7th, 2015 - To investigate whether severe and recurrent pre-eclampsia increase the risk for long-term maternal atherosclerotic disease. A population-based study compared the incidence of long-term atherosclerotic morbidity in a cohort of women who delivered in the years 1988-2012. The exposure variable was pre-eclampsia. Mean follow-up duration was 11.2 years. Kaplan-Meier survival curves were used to esti...

Angina pectoris and myocardial ischemia in the absence of obstructive coronary artery d...
https://doi.org/10.1016/j.jcin.2014.01.157
JACC. Cardiovascular Interventions; Radico F, Cicchitti V et. al.

Apr 21st, 2014 - Angina and myocardial ischemia without obstructive coronary artery disease are common clinical findings, often neglected for the assumption of a good prognosis. Most often, such patients are neither further investigated nor offered specific treatment beyond reassurance. However, the absence of significant coronary stenoses on angiography does not necessarily imply a "healthy" coronary tree. In ...

The global burden of ischemic heart disease in 1990 and 2010: the Global Burden of Dise...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181601
Circulation Moran AE, Forouzanfar MH et. al.

Feb 27th, 2014 - Ischemic heart disease (IHD) burden consists of years of life lost from IHD deaths and years of disability lived with 3 nonfatal IHD sequelae: nonfatal acute myocardial infarction, angina pectoris, and ischemic heart failure. Our aim was to estimate the global and regional burden of IHD in 1990 and 2010. Global and regional estimates of acute myocardial infarction incidence and angina and heart...

Efficacy of the long-acting nitro vasodilator pentaerithrityl tetranitrate in patients ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977134
European Heart Journal; Münzel T, Meinertz T et. al.

Sep 27th, 2013 - The organic nitrate pentaerithrityl tetranitrate (PETN) has been shown to have ancillary properties that prevent the development of tolerance and endothelial dysfunction. This randomized, double-blind, placebo-controlled, multicentre study ('CLEOPATRA' study) was designed to investigate the anti-ischaemic efficacy of PETN 80 mg b.i.d. (morning and mid-day) over placebo in patients with chronic ...

Effects of ivabradine and ranolazine in patients with microvascular angina pectoris.
https://doi.org/10.1016/j.amjcard.2013.02.045
The American Journal of Cardiology; Villano A, Di Franco A et. al.

Apr 5th, 2013 - Patients with microvascular angina (MVA) often have persistence of symptoms despite full classical anti-ischemic therapy. In this study, we assessed the effect of ivabradine and ranolazine in MVA patients. We randomized 46 patients with stable MVA (effort angina, positive exercise stress test [EST], normal coronary angiography, coronary flow reserve <2.5), who had symptoms inadequately controll...

Gender differences in symptoms during 60-second balloon occlusion of the coronary artery.
https://doi.org/10.1016/j.amjcard.2013.02.026
The American Journal of Cardiology; Tamura A, Naono S et. al.

Mar 18th, 2013 - Previous investigations have demonstrated the presence of gender differences in the symptoms of angina pectoris and acute coronary syndrome. However, most of these investigations have had certain limitations, including being retrospective, an interview-related bias, a various duration of myocardial ischemia, and a lack of multivariate analysis, all of which would have affected the results. Acco...

Spinal cord infarction with cervical angina.
https://doi.org/10.1016/j.jns.2012.11.005
Journal of the Neurological Sciences; Nakae Y, Johkura K et. al.

Dec 3rd, 2012 - Cervical angina is defined as chest pain resembling true cardiac angina but originating from disorders of the cervical spine. Cervical angina is caused by cervical spondylosis in most cases. A 66-year-old man presented with bilateral arm palsy after chest pain resembling angina pectoris. Neurological examination revealed motor and sensory disturbances of the C7 to T1 level, and magnetic resonan...

What have we learned about patients with heart failure and preserved ejection fraction ...
https://doi.org/10.1016/j.jacc.2012.04.064
Journal of the American College of Cardiology; Campbell RT, Jhund PS et. al.

Nov 12th, 2012 - Examination of patients with reduced and preserved ejection fraction in the DIG (Digitalis Investigation Group) trials and the CHARM (Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity) trials provides comparisons of outcomes in each of these types of heart failure. Comparison of the patients in these trials, along with the I-PRESERVE (Irbesartan in Heart Failure w...

Drug, devices, technologies, and techniques for blood management in minimally invasive ...
https://doi.org/10.1097/IMI.0b013e3182747699
Innovations (Philadelphia, Pa.); Menkis AH, Martin J et. al.

Nov 5th, 2012 - The objectives of this consensus conference were to evaluate the evidence for the efficacy and safety of perioperative drugs, technologies, and techniques in reducing allogeneic blood transfusion for adults undergoing cardiac surgery and to develop evidence-based recommendations for comprehensive perioperative blood management in cardiac surgery, with emphasis on minimally invasive cardiac surg...

Cardiac shock wave therapy for chronic refractory angina pectoris. A prospective placeb...
https://doi.org/10.1111/j.1755-5922.2012.00313.x
Cardiovascular Therapeutics; Schmid JP, Capoferri M et. al.

Sep 7th, 2012 - Cardiac shock wave therapy (CSWT) delivered to the myocardium increases capillary density and regional myocardial blood flow in animal experiments. In addition, nonenzymatic nitric oxide production and the upregulation of vascular growth factor's mRNA by CSWT have been described. The aim of the study was therefore to test its potential to relieve symptoms in patients with chronic stable angina ...

Stable angina pectoris with no obstructive coronary artery disease is associated with i...
https://doi.org/10.1093/eurheartj/ehr331
European Heart Journal; Jespersen L, Hvelplund A et. al.

Sep 13th, 2011 - Patients with chest pain and no obstructive coronary artery disease (CAD) are considered at low risk for cardiovascular events but evidence supporting this is scarce. We investigated the prognostic implications of stable angina pectoris in relation to the presence and degree of CAD with no obstructive CAD in focus. We identified 11 223 patients referred for coronary angiography (CAG) in 1998-20...

Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris.
https://doi.org/10.1016/j.jacc.2010.12.052
Journal of the American College of Cardiology; Rajendra NS, Ireland S et. al.

Aug 12th, 2011 - The aim of this study was to evaluate the effect of high-dose allopurinol on vascular oxidative stress (OS) and endothelial function in subjects with stable coronary artery disease (CAD). Allopurinol, a xanthine oxidase inhibitor, prolongs the time to chest pain during exercise in angina. We sought to ascertain whether allopurinol also improves endothelial dysfunction in optimally treated CAD p...