About 9,928 results
Ascertainment of Dementia Cases in the Spanish European Prospective Investigation into ... Preview
Neuroepidemiology Andreu-Reinón ME, Gavrila D et. al.

Nov 27th, 2018 - Cohort studies generally focus on a particular disease, although they offer the possibility of evaluating different outcomes with minimal additional investment. The objective of this study was to describe the methodology used to assess dementia in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Murcia study. The EPIC-Murcia cohort consists of 8,515 healthy participants (...

American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients

Nov 27th, 2018 - Background: Venous thromboembolism (VTE) is the third most common vascular disease. Medical inpatients, long-term care residents, persons with minor injuries, and long-distance travelers are at increased risk. Objective: These evidence-based guidelines from the American Society of Hematology (ASH) intend to support patients, clinicians, and others in decisions about preventing VTE in these grou...

American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism

Nov 27th, 2018 - Background: Modern diagnostic strategies for venous thromboembolism (VTE) incorporate pretest probability (PTP; prevalence) assessment. The ability of diagnostic tests to correctly identify or exclude VTE is influenced by VTE prevalence and test accuracy characteristics. Objective: These evidence-based guidelines are intended to support patients, clinicians, and health care professionals in VTE...

American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy

Nov 27th, 2018 - Background: Clinicians confront numerous practical issues in optimizing the use of anticoagulants to treat venous thromboembolism (VTE). Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians and other health care professionals in their decisions about the use of anticoagulants in the management of VTE. These guideline...

American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia

Nov 27th, 2018 - Background: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism. Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care prof...

American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy

Nov 27th, 2018 - Background: Venous thromboembolism (VTE) complicates ?1.2 of every 1000 deliveries. Despite these low absolute risks, pregnancy-associated VTE is a leading cause of maternal morbidity and mortality. Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians and others in decisions about the prevention and management of pre...

American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism

Nov 27th, 2018 - Background: Despite an increasing incidence of venous thromboembolism (VTE) in pediatric patients in tertiary care settings, relatively few pediatric physicians have experience with antithrombotic interventions. Objective: These guidelines of the American Society of Hematology (ASH), based on the best available evidence, are intended to support patients, clinicians, and other health care profes...

2018 ACC Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: A Report of the American...

Nov 26th, 2018 - Despite major therapeutic advances leading to improved outcomes over the past 2 decades, cardiovascular (CV) disease remains the leading cause of morbidity and mortality in patients with type 2 diabetes (T2D) (1). Over that time, the prevalence of T2D has increased, while the excess risk of adverse CV events in patients with T2D (compared with patients without diabetes) has remained largely unc...

Adjuvant Endocrine Therapy for Women With Hormone Receptor–Positive Breast Cancer: ASCO Clinical Practice Guideline Focused Update

Nov 19th, 2018 - Purpose: To update the ASCO clinical practice guideline on adjuvant endocrine therapy based on emerging data about the optimal duration of aromatase inhibitor (AI) treatment.MethodsASCO conducted a systematic review of randomized clinical trials from 2012 to 2018. Guideline recommendations were based on the Panel’s review of the evidence from six trials.ResultsThe six included studies of AI tre...

The Physical Activity Guidelines for Americans

Nov 12th, 2018 - Approximately 80% of US adults and adolescents are insufficiently active. Physical activity fosters normal growth and development and can make people feel, function, and sleep better and reduce risk of many chronic diseases. Keywords: exercise, obesity & weight management, lifestyle management

Redesigning Skin Cancer Early Detection and Care Using a New Mobile Health Application:... Preview
Dermatology (Basel, Switzerland); Janda M, Horsham C et. al.

Nov 8th, 2018 - Patients often detect melanoma themselves; therefore, regular skin self-examinations (SSEs) play an important role in the early detection and prompt treatment of melanoma. Mobile teledermoscopy is a technology that may facilitate consumer SSEs and rapid communication with a dermatologist. This paper describes the planned randomised controlled trial of an intervention to determine whether mobile...

2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task...

Nov 6th, 2018 - The purpose of this ACC/AHA/HRS guideline is to provide guidance to clinicians for the management of patients with bradycardia, or symptoms thought to be associated with bradycardia or cardiac conduction system disorders. Keywords: cardiology, bradycardia, cardiac arrhythmias, cardiovascular disorders, cardiology guidelines, arrhythmias

Standardized Photographic Documentation of Hidradenitis Suppurativa/Acne Inversa. Preview
Dermatology (Basel, Switzerland); Zouboulis CC, Nogueira da Costa A

Oct 29th, 2018 - Despite existing guidelines and methods for standardized clinical photography in dermatology and plastic surgery, human skin exhibits exquisite site-specific morphologies and functions, and each body region can exhibit an individual pathologic phenotype. The aim of this work was to develop a standardized, representative and reproducible documentation of the multilocular hidradenitis suppurativa...

Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: U... Preview
JAMA , Curry SJ et. al.

Oct 26th, 2018 - Intimate partner violence (IPV) and abuse of older or vulnerable adults are common in the United States but often remain undetected. In addition to the immediate effects of IPV, such as injury and death, there are other health consequences, many with long-term effects, including development of mental health conditions such as depression, posttraumatic stress disorder, anxiety disorders, substan...

2019 Canadian guideline for physical activity throughout pregnancy. Preview
British Journal of Sports Medicine; Mottola MF, Davenport MH et. al.

Oct 20th, 2018 - The objective is to provide guidance for pregnant women and obstetric care and exercise professionals on prenatal physical activity. The outcomes evaluated were maternal, fetal or neonatal morbidity, or fetal mortality during and following pregnancy. Literature was retrieved through searches of MEDLINE, EMBASE, PsycINFO, Cochrane Database of Systematic Reviews, Cochrane Central Register of Cont...

Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality... Preview
JAMA , Curry SJ et. al.

Oct 17th, 2018 - More than 35% of men and 40% of women in the United States are obese. Obesity is associated with health problems such as increased risk for coronary heart disease, type 2 diabetes, various types of cancer, gallstones, and disability. Obesity is also associated with an increased risk for death, particularly among adults younger than 65 years. To update the US Preventive Services Task Force (USPS...

ISUOG Practice Guidelines: role of ultrasound in screening for and follow-up of pre-eclampsia

Oct 15th, 2018 - Hypertensive disease of pregnancy affects up to 10% of pregnant women1 and the pooled global incidence of pre?eclampsia (PE) is approximately 3%2. Significant variations between developed and developing countries can be attributed to true differences or differences arising from data acquisition. PE and its complications are a major contributor to maternal and perinatal morbidity and mortality w...

Hypofractionated Radiation Therapy for Localized Prostate Cancer: Executive Summary of an ASTRO, ASCO, and AUA Evidence-Based Guideline

Oct 11th, 2018 - External beam radiation therapy (EBRT) is a standard definitive treatment for men with localized prostate cancer.1 The probability of cell survival after a dose of ionizing radiation is governed by the linear-quadratic model, in which curves of cell survival as a function of dose have an initial linear component followed by a steeper quadratic component. The relative weighting of each component...

European Society of Endocrinology Clinical Practice Guidelines on the management of adr... Preview
European Journal of Endocrinology; Fassnacht M, Dekkers OM et. al.

Oct 10th, 2018 - Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone-producing tumor with variable prognosis. The purpose of these guidelines is to provide clinicians with best possible evidence-based recommendations for clinical management of patients with ACC based on the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system. We predefined four main clinical q...

European headache federation guideline on idiopathic intracranial hypertension. Preview
The Journal of Headache and Pain; Hoffmann J, Mollan SP et. al.

Oct 10th, 2018 - Idiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of recent clinical studies are increasing the understanding of the disease and now provide the basis for evidence-based treatment strategies. The Embase, CDSR, CENTRAL, DARE and MEDLINE datab...