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Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020
https://www.cdc.gov/mmwr/volumes/69/wr/mm6914e4.htm
MMWR

Apr 5th, 2020 - In this preliminary description of pediatric U.S. COVID-19 cases, relatively few children with COVID-19 are hospitalized, and fewer children than adults experience fever, cough, or shortness of breath. Severe outcomes have been reported in children, including three deaths.

Practice recommendations for lung cancer radiotherapy during the COVID-19 pandemic: An ESTRO-ASTRO consensus statement
https://www.sciencedirect.com/science/article/pii/S0167814020301821
Radiotherapy and Oncology;

Apr 5th, 2020 - The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients and healthcare staff. An international group of experts in lung cancer radiotherapy established this practice recommendation pertaining to whether and how to adapt radiotherapy for lung cancer in the COVID-19 pandemic.

As ACA marks 10th anniversary, MH care even more critical during COVID‐19
https://onlinelibrary.wiley.com/doi/full/10.1002/mhw.32292
Mental Health Weekly;

Mar 26th, 2020 - March 23, 2020, marked the 10th anniversary of the Affordable Care Act (ACA), which, despite some ups and downs over the past decade, has expanded the scope of coverage for millions of people with mental illnesses and substance use disorders (SUDs).

Patients taking ACE-i and ARBs who contract COVID-19 should continue treatment, unless otherwise advised by their physician
https://newsroom.heart.org/news/patients-taking-ace-i-and-arbs-who-contract-covid-19-should-continue-treatment-unless-otherwise-advised-by-their-physician
American Heart Association;

Mar 16th, 2020 - As the global impact of COVID-19 rises, the scientific community continues to evaluate the clinical impact and health care needs of patients with cardiovascular disease, who are at increased risk for serious complications with COVID-19. Together, the American Heart Association (AHA), the Heart Failure Society of America (HFSA) and the American College of Cardiology (ACC) jointly published this ...

WHO Coronavirus Resources
https://www.who.int/health-topics/coronavirus
World Health Organization; WHO

Mar 10th, 2020 - Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). A novel coronavirus (nCoV) is a new strain that has not been previously identified in humans.

The role of environmental factors on transmission rates of the COVID-19 outbreak: An initial assessment in two spatial scales.
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3552677

Mar 8th, 2020 - A novel coronavirus (SARS-CoV-2) was identified in Wuhan, Hubei Province, China, in December 2019 and has caused over 240,000 cases of COVID-19 worldwide as of March 19, 2020. Previous studies have supported an epidemiological hypothesis that cold and dry environments facilitate the survival and spread of droplet-mediated viral diseases, and warm and humid environments see attenuated viral ...

Working to Improve Immunotherapy for Lung Cancer
https://directorsblog.nih.gov/tag/nsclc/
NIH.gov NIH Director

Feb 2nd, 2020 - For those who track cancer statistics, this year started off on a positive note with word that lung cancer deaths continue to decline in the United States [1]. While there’s plenty of credit to go around for that encouraging news—and continued reduction in smoking is a big factor—some of this progress likely can be ascribed to a type of immunotherapy, called PD-1 inhibitors. This revolutionary ...

Psoriasis & Genetics
https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3384
Advances in Dermatology and Venereology; Dand N, et al

Jan 29th, 2020 - Psoriasis is a common inflammatory skin disease caused by the interplay between multiple genetic and environmental risk factors. This review summarises recent progress in elucidating the genetic basis of psoriasis, particularly through large genome-wide association studies. We illustrate the power of genetic analyses for disease stratification. Psoriasis can be stratified by phenotype (common p...

Association Between Body Mass Index and Overall Survival With Immune Checkpoint Inhibitor Therapy for Advanced Non–Small Cell Lung Cancer
https://jamanetwork.com/journals/jamaoncology/article-abstract/2757521
JAMA Oncology; Kichenadasse, et al

Dec 25th, 2019 - Is high body mass index associated with survival outcomes with atezolizumab therapy, an immune checkpoint inhibitor, in patients with non–small cell lung cancer?

Hair dye and chemical straightener use and breast cancer risk in a large US population of black and white women
https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32738
International Journal of Cancer; Carolyn E. Eberle et al

Dec 4th, 2019 - Many hair products contain endocrine‐disrupting compounds and carcinogens potentially relevant to breast cancer. Products used predominately by black women may contain more hormonally‐active compounds. In a national prospective cohort study, we examined the association between hair dye and chemical relaxer/straightener use and breast cancer risk by ethnicity.

Immune Status and Associated Mortality After Cancer Treatment Among Individuals With HIV in the Antiretroviral Therapy Era
https://jamanetwork.com/journals/jamaoncology/article-abstract/2757078
JAMA Oncology; Calkins KL, et al

Dec 4th, 2019 - What is the association between cancer treatment and CD4 count and HIV RNA level, and how are these markers associated with all-cause mortality among people with HIV?

Hereditary Cancer Syndromes and Risk Assessment ACOG COMMITTEE OPINION, Number 793
https://journals.lww.com/greenjournal/Fulltext/2019/12000/Hereditary_Cancer_Syndromes_and_Risk_Assessment_.39.aspx
Obstetrics & Gynecology; ACOG

Nov 30th, 2019 - A hereditary cancer syndrome is a genetic predisposition to certain types of cancer, often with onset at an early age, caused by inherited pathogenic variants in one or more genes. Most hereditary cancer syndromes exhibit autosomal dominant inheritance. The most common hereditary cancer syndromes related to women’s cancer include hereditary breast and ovarian cancer syndrome, Lynch syndrome, Li...

Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines
https://annals.org/aim/fullarticle/2756145/breast-cancer-screening-diagnosis-synopsis-european-breast-guidelines
Annals of Internal Medicine; Holger J. Schünemann, et al

Nov 30th, 2019 - This synopsis of the European Breast Guidelines provides recommendations regarding organized screening programs for women aged 40 to 75 years who are at average risk. The recommendations address digital mammography screening and the addition of hand-held ultrasonography, automated breast ultrasonography, or magnetic resonance imaging compared with mammography alone. The recommendations also dis...

Anticoagulation-Related Major Bleeding in Patients With Atrial Fibrillation
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.043318
Circulation Adam J. Nelson et al

Nov 30th, 2019 - Antithrombotic therapy for cardiovascular disease revolves around balancing 2 key outcomes—reducing ischemic events without increasing bleeding. There has been a subtle but progressive shift away from a dominant focus on reducing ischemic events to a more balanced and explicit interest in avoiding bleeding. Bleeding is common and, in part, an expected result of the increased use of anticoagulan...

Association of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2754091
JAMA Internal Medicine; Rob F. Walker, et al

Nov 30th, 2019 - Testosterone therapy is increasingly prescribed in patients without a diagnosis of hypogonadism. This therapy may be associated with increased risk of venous thromboembolism (VTE) through several mechanisms, including elevated hematocrit levels, which increase blood viscosity.

Quantitative Blood Loss in Obstetric Hemorrhage - ACOG COMMITTEE OPINION, Number 794
https://journals.lww.com/greenjournal/Fulltext/2019/12000/Quantitative_Blood_Loss_in_Obstetric_Hemorrhage_.40.aspx
Obstetrics & Gynecology;

Nov 30th, 2019 - Postpartum hemorrhage causes approximately 11% of maternal deaths in the United States and is the leading cause of death that occurs on the day of birth. Importantly, 54–93% of maternal deaths due to obstetric hemorrhage may be preventable. Studies that have evaluated factors associated with identification and treatment of postpartum hemorrhage have found that imprecise health care provider est...

Some melanomas may start in hair follicles
https://www.nih.gov/news-events/nih-research-matters/some-melanomas-may-start-hair-follicles
NIH

Nov 30th, 2019 - A rare form of skin cancer may sometimes start with cancer-causing mutations in hair follicle stem cells. A better understanding of how melanoma arises may lead to ways to detect and treat the disease earlier.

NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 1.2020
https://jnccn.org/view/journals/jnccn/17/12/article-p1464.xml
JNCCN Ettinger DS, et al

Nov 30th, 2019 - The NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC) address all aspects of management for NSCLC. These NCCN Guidelines Insights focus on recent updates in immunotherapy. For the 2020 update, all of the systemic therapy regimens have been categorized using a new preference stratification system; certain regimens are now recommended as “preferred interventions,” whereas others are categori...

Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology
https://jnccn.org/view/journals/jnccn/17/12/article-p1529.xml
JNCCN Gilligan T, et al

Nov 30th, 2019 - Testicular cancer is relatively uncommon and accounts for <1% of all male tumors. However, it is the most common solid tumor in men between the ages of 20 and 34 years, and the global incidence has been steadily rising over the past several decades. Several risk factors for testicular cancer have been identified, including personal or family history of testicular cancer and cryptorchidism. Test...

Pelvic Organ Prolapse ACOG Practice Bulletin, Number 214
https://journals.lww.com/greenjournal/Abstract/2019/11000/Pelvic_Organ_Prolapse__ACOG_Practice_Bulletin,.44.aspx
Obstetrics & Gynecology;

Nov 29th, 2019 - Pelvic organ prolapse (POP) is a common, benign condition in women. For many women it can cause vaginal bulge and pressure, voiding dysfunction, defecatory dysfunction, and sexual dysfunction, which may adversely affect quality of life. Women in the United States have a 13% lifetime risk of undergoing surgery for POP (1). Although POP can occur in younger women, the peak incidence of POP sympto...