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About 447,144 results
Shaji Kumar, MD, on Multiple Myeloma: Phase III Results on Carfilzomib, Lenalidomide, Bortezomib, and Dexamethasone
https://ascopost.com/videos/asco20-virtual-scientific-program/shaji-kumar-on-carfilzomib-lenalidomide-bortezomib-and-dexamethasone-in-multiple-myeloma/

May 29th, 2020 - Shaji Kumar, MD, of the Mayo Clinic, discusses findings from the ENDURANCE trial, which showed bortezomib, lenalidomide, and dexamethasone should remain the standard of care in patients with newly diagnosed standard- or intermediate-risk multiple myeloma, for whom early autologous stem cell transplant is not intended (Abstract LBA3).

Nancy U. Lin, MD, on Metastatic Breast Cancer: Tucatinib, Trastuzumab, and Capecitabine
https://ascopost.com/videos/asco20-virtual-scientific-program/nancy-lin-on-tucatinib-trastuzumab-and-capecitabine-for-metastatic-breast-cancer/

May 29th, 2020 - Nancy U. Lin, MD, of Dana-Farber Cancer Institute, discusses the HER2CLIMB study of patients with previously treated HER2-positive metastatic breast cancer that had metastasized to the brain. Adding tucatinib to trastuzumab and capecitabine doubled the intracranial response rate and reduced the risk of death by nearly half, compared with trastuzumab plus capecitabine (Abstract 1005).

Study Finds Patients With Lung Cancer Infected With COVID-19 Are at High Risk for Hospitalization
https://ascopost.com/news/may-2020/study-finds-patients-with-lung-cancer-infected-with-covid-19-recently-treated-with-chemotherapy-at-higher-risk-of-death/

May 28th, 2020 - Data from the global TERAVOLT Consortium, which is investigating the impact of COVID-19 infection on patients with thoracic cancers, have found that these patients are at high risk for hospitalization and death. Prior use of chemotherapy was associated with an increased risk of mortality, as was the use of steroids or anticoagulants. Prior administration of immunotherapy and chemoimmunotherapy ...

Adjuvant Osimertinib ‘Exceeds Expectations’ in Early-Stage EGFR-Positive NSCLC
https://ascopost.com/news/may-2020/adjuvant-osimertinib-exceeds-expectations-in-egfr-positive-nsclc/

May 27th, 2020 - Adjuvant osimertinib significantly improved disease-free survival compared with placebo in patients with stage IB to IIIA ­EGFR-mutated non–small cell lung cancer (NSCLC) who underwent complete resection of primary tumor and received chemotherapy if indicated. These results from the first interim analysis of the phase III ADAURA trial were reported at the ASCO20 Virtual Scientific Program and f...

Roy S. Herbst, MD, PhD, on NSCLC: Osimertinib in Stage Ib–IIIa EGFR Mutation–Positive Disease
https://ascopost.com/videos/asco20-virtual-scientific-program/roy-herbst-on-osimertinib-in-stage-ib-iiia-egfr-mutation-positive-nsclc/

May 29th, 2020 - Roy S. Herbst, MD, PhD, of Yale Cancer Center, discusses data from the ADAURA study, which showed that compared with placebo, osimertinib as adjuvant therapy after complete tumor resection reduced the risk of disease recurrence or death by 79% in patients with non–small cell lung cancer (Abstract LBA5).

New Data Support Debulking to Prolong Survival in Women With Platinum-Sensitive Recurrent Ovarian Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200180/full/

May 28th, 2020 - DESKTOP III became the first phase III, prospective, randomized trial to show an association between improved overall survival (OS) and secondary cytoreductive surgery in women with platinum-sensitive recurrent ovarian cancer (PSROC), offering hope for people with a condition that results in nearly 14,000 deaths annually. Data were presented during the ASCO20 Virtual Scientific Program (Abstrac...

Palliative Care Improves Well-Being and QoL in Phase I Cancer Trial Participants
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200184/full/

May 28th, 2020 - Participants in phase I oncology trials represent a patient population new to palliative care. These patients typically have remarkable symptoms, with a symptom burden comparable to other patients with cancer.1 Thomas J. Smith, MD, FASCO, of Johns Hopkins University, presented the results of a randomized trial evaluating a palliative care intervention (PCI) compared with usual care (UC) for pat...

Effect of Veliparib With or Without Cisplatin in Breast Cancer: Results of SWOG S1416
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200176/full/

May 28th, 2020 - The Southwest Oncology Group (SWOG) 1416 phase II trial was designed to compare the efficacy of the PARP inhibitor veliparib plus cisplatin versus cisplatin alone in patients with metastatic and/or locally recurrent triple-negative breast cancer (TNBC) or BRCA1 or BRCA2 germline mutation–associated HER2-negative metastatic breast cancer. Priyanka Sharma, MD, of the University of Kansas Medical ...

Pembrolizumab Monotherapy Demonstrates PFS Benefit Over Brentuximab Vedotin in Relapsed or Refractory Classical Hodgkin Lymphoma
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200193/full/

May 28th, 2020 - Pembrolizumab monotherapy demonstrated a progression-free survival (PFS) benefit over brentuximab vedotin (BV) in patients with relapsed or refractory (R/R) classical Hodgkin lymphoma, according to the results from the phase III international KEYNOTE-204 trial (Abstract 8005). Clinically meaningful improvement in PFS was observed in all subgroups tested, including patients who did not receive a...

Sentinel Node Biopsy Strategy Equivalent to Neck Dissection in T1-T2NO Oropharyngeal and Oral Cancers
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200192/full/

May 28th, 2020 - In a randomized multicenter study, a strategy based on sentinel node biopsy (SNB) was equivalent to elective neck dissection (END) in the management of T1-T2N0 oral and oropharyngeal squamous cell carcinomas, with comparable 2-year neck recurrence-free survival (RFS) and lower morbidity in year 1 after surgery (Abstract 6501). Renaud Garrel, MD, of CHU Montpellier, France, presented the results...

Selinexor/Bortezomib/Dexamethasone Triplet Improves PFS, ORR in Multiple Myeloma
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200181/full/

May 28th, 2020 - Once-weekly selinexor, bortezomib, and dexamethasone (SVd) for relapsed/refractory multiple myeloma (MM) significantly improved progression-free survival (PFS) and overall response rate (ORR) when compared with twice-weekly bortezomib and dexamethasone (Vd), according to initial results from the phase III BOSTON trial (Abstract 8501).

KarMMa: BCMA-Targeting CAR T Excellent Option for Relapsed/Refractory Myeloma
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200194/full/

May 28th, 2020 - CAR T-cell therapy with BCMA-targeting idecabtagene-vicleucel (ide-cel) resulted in deep and durable responses in heavily pretreated patients with relapsed/refractory multiple myeloma, according to phase II data from the KarMMa trial (Abstract 8503).

Early Data Show Bispecific Antibody Teclistamab Safe, Active in Relapsed/Refractory Multiple Myeloma
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200175/full/

May 28th, 2020 - Teclistamab, a IgG-4 bispecific antibody targeting BCMA and CD3, appears to be safe in patients with relapsed or refractory multiple myeloma, according to phase I data presented during the ASCO20 Virtual Scientific Program (Abstract 100).

Donafenib Improves OS in Hepatocellular Carcinoma Compared With Sorafenib
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200179/full/

May 28th, 2020 - Donafenib significantly improved overall survival (OS) rates compared with sorafenib in patients with hepatocellular carcinoma (HCC) and did so with favorable safety and tolerability, according to a new study (Abstract 4506).

ADJUVANT-CTONG 1104 Results Underscore the Value of Using EGFR-Targeted Therapy in EGFR-Mutated NSCLC
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200182/full/

May 28th, 2020 - During the 2017 ASCO Annual Meeting, investigators of the ADJUVANT-CTONG 1104 trial first reported that postsurgical treatment with gefitinib conferred a significant 10.7-month improvement in disease-free survival (DFS) compared with standard doublet chemotherapy in patients with stage II-IIIA EGFR-positive non–small cell lung cancer (NSCLC), thus meeting the primary study endpoint (HR 0.60, 95...

Trastuzumab Fails to Improve DFS When Added to Trimodality Therapy for Operable Esophageal Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200178/full/

May 28th, 2020 - Although HER-targeted therapy represents a standard of care for many HER2-positive malignancies, data supporting its benefit for patients with early-stage HER2-overexpressing esophageal adenocarcinoma are lacking. Results of the RTOG 1010 trial demonstrated that adding trastuzumab both before and after chemoradiotherapy and surgery did not significantly improve disease-free survival (DFS) beyon...

Final IDEA Collaboration Results Support Just 3 Months of Adjuvant CAPOX for Most Patients With Stage III Colon Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200177/full/

May 28th, 2020 - Prospective evaluation of nearly 13,000 individuals with stage III colon cancer found minimal difference in 5-year overall survival (OS) with 3 versus 6 months of adjuvant CAPOX or FOLFOX for the majority of patients, according to the final results of the International Duration Evaluation of Adjuvant Chemotherapy (IDEA) collaboration (Abstract 4004). In contrast, the shorter treatment course pr...

Dr. Sondos Zayed Receives the Philip Francis Mulvey, III, Endowed Merit Award for Research on Opioid Addiction Risk in Patients With Head and Neck Cancer
https://dailynews.ascopubs.org/do/10.5555/ADN.20.200185/full/

May 28th, 2020 - A new merit award memorializing a remarkable man’s lifetime mission of mentorship is honoring a particularly appropriate inaugural recipient—Sondos Zayed, MD, an early-career resident clinical investigator at Western University, Canada.

Three Years of Imatinib Improves OS in High-Risk Operable GIST
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200183/full/

May 28th, 2020 - Approximately half of deaths can be avoided with the use of 3 years of adjuvant imatinib in the first decade after surgery for high-risk gastrointestinal stromal tumors (GIST), according to long-term data from the Scandinavian Sarcoma Group XVIII/German trial (Abstract 11503).

Triplet Combination Considered New Standard of Care for Patients With HER2-Positive Metastatic Breast Cancer, Brain Metastases
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200164/full/

May 28th, 2020 - Exploratory analyses conducted in a subset of heavily pretreated patients with brain metastases enrolled on the HER2CLIMB trial found that tucatinib in combination with trastuzumab and capecitabine reduces the risk of intracranial (IC) progression and death in patients with HER2-positive metastatic breast cancer (MBC; Abstract 1005). Nancy U. Lin, MD, of Dana-Farber Cancer Institute, presented ...

Upfront Radiation Added to TKI Therapy Improves Outcomes in Oligometastatic NSCLC
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200171/full/

May 28th, 2020 - The addition of stereotactic body radiation therapy (SBRT) to tyrosine kinase inhibitor (TKI) therapy yielded longer progression-free survival (PFS) and overall survival (OS) than TKI therapy alone in patients with EGFR-mutant oligometastatic non–small cell lung cancer (NSCLC), according to an interim analysis of an open-label phase III trial presented during the ASCO20 Virtual Scientific Progr...

Palliative Care Improves Quality of Life in Patients With AML
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200172/full/

May 28th, 2020 - When patients with acute myeloid leukemia (AML) undergo intensive chemotherapy treatment, their quality of life (QoL) and mood are negatively affected. Areej El-Jawahri, MD, of Massachusetts General Hospital, presented the results of a multicenter study conducted in patients with AML to determine if integrated palliative and oncology care could improve QoL and other important aspects of patient...

T-DM1 Does Not Improve Safety or Efficacy in HER2-Positive Early Breast Cancer; Favorable iDFS Reported
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200162/full/

May 28th, 2020 - Findings from the primary analysis of the KAITLIN trial suggest that replacement of adjuvant taxane with trastuzumab emtansine (T-DM1) does not improve survival or safety for patients with HER2-positive early-stage breast cancer (Abstract 500). However, both treatments demonstrated outstanding long-term invasive disease–free survival (iDFS) in a high-risk population. Study author Nadia Harbeck,...

18F-DCFPyL–PET/CT Imaging Improves Diagnostic Capability in Relapsed Prostate Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200168/full/

May 28th, 2020 - Imaging with 18F-DCFPyL–PET/CT was found to be diagnostically effective, often guiding a change in treatment plan, in men with biochemically relapsed prostate cancer, according to the results of the phase III CONDOR study presented during the ASCO20 Virtual Scientific Program (Abstract 5501).

Apalutamide, Darolutamide, Enzalutamide Yield OS Benefit in nmCRPC
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200161/full/

May 28th, 2020 - Final survival results from three randomized, placebo-controlled trials, along with a safety analysis across all three, are helping to clarify the treatment landscape for nonmetastatic castration-resistant prostate cancer (nmCRPC). The results will be presented during the ASCO20 Virtual Scientific Program.

Strategies Emerge for Chemotherapy De-escalation in HER2-Positive Breast Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200163/full/

May 28th, 2020 - Two studies presented during the ASCO20 Virtual Scientific Program show the potential to de-escalate chemotherapy in the setting of dual HER2 blockade for patients with HER2-positive breast cancer.

https://dailynews.ascopubs.org/do/10.1200/ADN.20.200143/full/
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200143/full/

May 19th, 2020 - In the phase III PROfound trial (NCT02987543), men with metastatic castration-resistant prostate cancer (mCRPC) who had disease progression while receiving enzalutamide or abiraterone and who had homologous recombination repair (HRR) gene alterations demonstrated longer progression-free survival and better measures of response when treated with olaparib than enzalutamide or abiraterone.1 Now, t...

Integrated Tumor and Immune Cell Multiomic Analyses Predict ICB Response in Advanced Melanoma
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200165/full/

May 28th, 2020 - Immunoglobulin (Ig) gene rearrangements, expressed tumor mutation burden (TMB), tumor aneuploidy, and pre-existing T- and B-cell immunity may predict response to immune checkpoint blockade (ICB) and subsequent prognosis in patients with advanced melanoma, according to a study (Abstract 10009) presented by Valsamo Anagnostou, MD, PhD, of the Bloomberg-Kimmel Institute for Cancer Immunotherapy at...

Dr. Alice Yu, Pioneer in Immunotherapy for Neuroblastoma, to Receive Pediatric Oncology Award
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200152/full/

May 19th, 2020 - Alice Yu, MD, PhD, of the University of California San Diego School of Medicine, will receive the 2020 Pediatric Oncology Award. The award, first presented in 2002, recognizes a pediatric oncologist who has demonstrated outstanding leadership or achievement in the field.

Interim Analysis of GAIN-2 Indicates Dose-Dense Chemotherapy Regimens Are Equivalent
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200142/full/

May 28th, 2020 - An interim analysis of the GAIN-2 study in patients with high-risk early-stage breast cancer indicated that the use of neoadjuvant/adjuvant intense, dose-dense epirubicin, nab-paclitaxel, and cyclophosphamide (iddEnPC) and dose-dense, dose-tailored epirubicin/cyclophosphamide followed by dose-dense, dose-tailored docetaxel (dtEC-dtD) were equivalent (Abstract 516).

Addition of Ublituximab to Ibrutinib Appears Safe and Effective for Patients With High-Risk Chronic Lymphocytic Leukemia
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200124/full/

May 12th, 2020 - Although chronic lymphocytic leukemia (CLL) has a relatively high 5-year survival rate (85% for people age 20 and older), effective treatments for advanced disease are still needed. Use of combination or monotherapy Bruton’s tyrosine kinase (BTK) inhibitors has shown promise for people with CLL, with the BTK inhibitor ibrutinib now considered a standard of care for patients of any age. However,...

Study Reveals Association Between Immune Cell Profiles and Functional Decline in Women With Breast Cancer Receiving Chemotherapy
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200120/full/

May 12th, 2020 - Higher prechemotherapy lymphocytes and lower neutrophil:lymphocyte ratio (NLR) were found to correlate with an increased risk of functional decline and reduced ability to regain baseline physical function in women with breast cancer in a recent study from the University of Rochester National Cancer Institute Community Oncology Research Program (Abstract 549). The study, which will be presented ...

Never Too Late: Smoking Cessation Just Before Lung Cancer Diagnosis Leads to Survival Benefit
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200126/full/

May 12th, 2020 - A retrospective study examining the time since a patient quit smoking before a lung cancer diagnosis and the subsequent survival outcomes after the lung cancer diagnosis indicated that it is never too late to stop smoking (Abstract 1512). Among patients diagnosed with lung cancer who had quit smoking within 2 years of lung cancer diagnosis, risk of death from any cause was reduced by 12% when c...

NK Cells Emerge As Potentially Useful Targets for Extending Survival in Triple-Negative Breast Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200119/full/

May 12th, 2020 - Triple-negative breast cancer (TNBC) is a highly aggressive disease that is resistant to endocrine therapy and anti-HER2 molecular targeted treatments. However, results from a new study suggest that natural killer (NK) cells may be an effective alternative focus for future immune-based treatments to improve survival in patients with TNBC (Abstract 510).

Dr. Betty Ferrell Honored With the Walther Cancer Foundation Palliative and Supportive Care in Oncology Endowed Award
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200140/full/

May 12th, 2020 - Betty Ferrell, PhD, MA, FAAN, FPCN, calls it her “lightning bolt moment” when a gravely ill patient with cancer beseeched her for relief from his terrible pain—and set her on a lifetime of groundbreaking work in palliative care.

Pharmacokinetically Guided Dose Optimization of Pazopanib Is Feasible in Daily Practice, Efficacy Not Determined
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200127/full/

May 12th, 2020 - Results from the Dutch Pharmacology Oncology Group (DPOG) therapeutic drug monitoring (TDM) study of pazopanib in patients with renal cell carcinoma (RCC) and soft tissue sarcoma (STS) demonstrated that pharmacokinetically guided dose optimization using cost-neutral interventions can be achieved in daily practice (Abstract 3598).

PROSPER RCC Explores Neoadjuvant and Adjuvant Immunotherapy in Kidney Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200128/full/

May 12th, 2020 - Despite robust efforts, no adjuvant systemic therapy has succeeded in prolonging overall survival beyond that achieved with surgery alone in patients with nonmetastatic renal cell carcinoma (RCC). The phase III PROSPER RCC trial, along with similar studies, may well break that trend, ousting postsurgical surveillance as the current standard of care (Abstract TPS5101)

Tisagenlecleucel Outcomes in Trial of Pediatric, Young Adult R/R ALL Are Consistent With Those Previously Reported
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200130/full/

May 12th, 2020 - In pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia (ALL) who received prior blinatumomab exposure or inotuzumab ozogamicin as bridging therapy, treatment with tisagenlecleucel is associated with consistent adverse event and efficacy outcomes previously reported in the ELIANA trial, according to the results of the B2001X study (Abstract 10518).

Considerable Variation Exists in Receipt of Complete Diagnostic Evaluations for Myelodysplastic Syndromes Among Medicare Patients
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200129/full/

May 12th, 2020 - A substantial proportion of Medicare patients with myelodysplastic syndromes (MDS) do not undergo a complete diagnostic evaluation (CDE), including a bone marrow biopsy, to confirm their disease (Abstract 7555).

Dr. Pasi A. Jänne Honored With the Science of Oncology Award
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200139/full/

May 12th, 2020 - Pasi A. Jänne, MD, PhD, professor of medicine at Harvard Medical School, director of the Chen-Huang Center for EGFR-Mutant Lung Cancers, and director of the Belfer Center for Applied Cancer Sciences at Dana-Farber Cancer Institute, has been named the 2020 Science of Oncology Award recipient for his career-long contributions to advancing therapies for lung cancer.

Combination Pembrolizumab Plus Intermittent Dabrafenib and Trametinib Found to Be Safe, Effective in Patients with Melanoma Harboring the BRAFV600 Mutation
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200132/full/

May 12th, 2020 - Combination pembrolizumab plus intermittent dabrafenib and trametinib was found to be more tolerable than continuous triple therapy in patients with melanoma harboring the BRAFV600 mutation, according to the latest results from the IMPemBra trial (Abstract 10021).

Adoption of Augmented Intelligence Could Increase Timely Referral to Palliative Care
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200131/full/

May 12th, 2020 - Augmented intelligence (AI) could help in the timely integration of palliative care into the treatment plan of patients with advanced cancer, according to a large community practice study (Abstract 12015).

Locoregional Treatment of Intact Primary Tumor Does Not Improve Survival, HRQoL in Metastatic Breast Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200210/full/

May 30th, 2020 - Early initiation of locoregional treatment (LRT) of an intact primary tumor (IPT) in women with de novo stage IV metastatic breast cancer does not appear to prolong survival or improve health-related quality of life (HRQoL) compared with systemic therapy alone, according to a new study (Abstract LBA2). Seema A. Khan, MD, of the Northwestern Memorial Hospital, presented these findings during the...

Off-the-shelf CAR-T regimen safe for advanced lymphoma
https://www.healio.com/hematology-oncology/lymphoma/news/online/{87e5706a-8ecb-4473-95b8-60f27a6e22cb}/off-the-shelf-car-t-regimen-safe-for-advanced-lymphoma

May 31st, 2020 - An allogeneic chimeric antigen T-cell therapy plus an anti-CD52 monoclonal antibody appeared safe for certain patients with large B-cell or follicular lymphoma, according to study data presented during the ASCO20 Virtual Scientific Program.

CAR-T continues to show durable responses in indolent non-Hodgkin lymphoma
https://www.healio.com/hematology-oncology/lymphoma/news/online/{b5b2d115-7000-4df9-8743-26711c3bbde1}/car-t-continues-to-show-durable-responses-in-indolent-non-hodgkin-lymphoma

May 30th, 2020 - Axicabtagene ciloleucel induced a 93% response rate among patients with relapsed or refractory indolent non-Hodgkin lymphoma, according to interim results of the phase 2 ZUMA-5 trial presented during the ASCO20 Virtual Scientific Program.

Axitinib prolongs PFS in metastatic adenoid cystic carcinoma
https://www.healio.com/hematology-oncology/head-neck-cancer/news/online/{40a4c150-78fc-4a61-ae96-5a8b84f9c6ee}/axitinib-prolongs-pfs-in-metastatic-adenoid-cystic-carcinoma

May 30th, 2020 - Axitinib significantly extended PFS among patients with recurred or metastatic adenoid cystic carcinoma, according to results of a randomized phase 2 study presented during the ASCO20 Virtual Scientific Program.

Early local therapy fails to extend survival in metastatic breast cancer subset
https://www.healio.com/hematology-oncology/breast-cancer/news/online/{fce1cd33-c5fd-4bf8-8336-97281967a80c}/early-local-therapy-fails-to-extend-survival-in-metastatic-breast-cancer-subset

May 31st, 2020 - Early local therapy did not prolong survival among women with de novo metastatic breast cancer and intact primary tumors, according to randomized phase 3 study results presented during the ASCO20 Virtual Scientific Program.

Children with Down syndrome, ALL at higher risk for poor outcomes
https://www.healio.com/hematology-oncology/leukemia/news/online/{4b3c1cc4-4e4a-462e-b738-7ee6b1d20fd3}/children-with-down-syndrome-all-at-higher-risk-for-poor-outcomes

May 30th, 2020 - Children with Down syndrome and acute lymphoblastic leukemia continue to experience poorer outcomes than children with ALL who do not have Down syndrome, according to study results presented during the ASCO20 Virtual Scientific Program.

Ramucirumab-gemcitabine combination confers OS benefit in malignant pleural mesothelioma
https://www.healio.com/hematology-oncology/lung-cancer/news/online/{2cadd0d4-adb1-4d44-8ef3-4f1f2b3fa922}/ramucirumab-gemcitabine-combination-confers-os-benefit-in-malignant-pleural-mesothelioma

May 29th, 2020 - The addition of ramucirumab to gemcitabine significantly improved survival among patients with malignant pleural mesothelioma, according to randomized phase 2 study results presented during the ASCO20 Virtual Scientific Program.

Metronomic capecitabine maintenance extends DFS in triple-negative breast cancer
https://www.healio.com/hematology-oncology/breast-cancer/news/online/{3c339a48-87d5-48c1-ad53-432291e3e553}/metronomic-capecitabine-maintenance-extends-dfs-in-triple-negative-breast-cancer

May 29th, 2020 - A year of maintenance therapy with metronomic capecitabine after standard treatment extended DFS among women with operable triple-negative breast cancer, according to study results presented at ASCO20 Virtual Scientific Program.