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Quantifying Viral Particle Aerosolization Risk During Tracheostomy Surgery and Tracheos...
https://doi.org/10.1001/jamaoto.2021.1383
JAMA Otolaryngology-- Head & Neck Surgery; Berges AJ, Lina IA et. al.

Jul 23rd, 2021 - During respiratory disease outbreaks such as the COVID-19 pandemic, aerosol-generating procedures, including tracheostomy, are associated with the risk of viral transmission to health care workers. To quantify particle aerosolization during tracheostomy surgery and tracheostomy care and to evaluate interventions that minimize the risk of viral particle exposure. This comparative effectiveness s...

Efficacy of "Essential Iodine Drops" against Severe Acute Respiratory Syndrome-Coronavi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270147
PloS One; Köntös Z

Jul 10th, 2021 - Aerosolization of respiratory droplets is considered the main route of coronavirus disease 2019 (COVID-19). Therefore, reducing the viral load of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) shed via respiratory droplets is potentially an ideal strategy to prevent the spread of the pandemic. The in vitro virucidal activity of intranasal Povidone-Iodine (PVP-I) has been demonstra...

Design and proof of concept for targeted phage-based COVID-19 vaccination strategies wi...
https://doi.org/10.1073/pnas.2105739118
Proceedings of the National Academy of Sciences of the Un... Staquicini DI, Tang FHF et. al.

Jul 9th, 2021 - Development of effective vaccines against coronavirus disease 2019 (COVID-19) is a global imperative. Rapid immunization of the entire human population against a widespread, continually evolving, and highly pathogenic virus is an unprecedented challenge, and different vaccine approaches are being pursued. Engineered filamentous bacteriophage (phage) particles have unique potential in vaccine de...

Aerosol Generation During Laryngology Procedures in the Operating Room.
https://doi.org/10.1002/lary.29729
The Laryngoscope; Zheng M, Lui C et. al.

Jul 3rd, 2021 - Severe acute respiratory syndrome coronavirus-2 spreads through respiratory fluids. We aim to quantify aerosolized particles during laryngology procedures to understand their potential for transmission of infectious aerosol-based diseases. Prospective quantification of aerosol generation. Airborne particles (0.3-25 μm in diameter) were measured during live-patient laryngology surgeries using an...

Some Nasogastric Intubation Procedures Lead to Less Aerosolization Than Feared
https://www.medscape.com/viewarticle/952317

Jun 2nd, 2021 - Nasogastric intubation for esophageal manometry or impedance monitoring does not generate significant aerosol particles and is associated with minimal droplet spread, according to a Belgian study presented at the annual Digestive Disease Week® (DDW). These findings suggest that standard personal protective equipment and appropriate patient positioning are likely sufficient to protect health car...

SARS-CoV-2 aerosol generation during respiratory equipment reprocessing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156569
Antimicrobial Resistance and Infection Control; Moraes Bruna CQ, Ciofi-Silva CL et. al.

May 29th, 2021 - Aerosolization may occur during reprocessing of medical devices. With the current coronavirus disease 2019 pandemic, it is important to understand the necessity of using respirators in the cleaning area of the sterile processing department. To evaluate the presence of severe acute respiratory syndrome coronavirus (SARS-CoV-2) in the air of the sterile processing department during the reprocessi...

Predictors of failure of high flow nasal cannula failure in acute hypoxemic respiratory...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133822
Respiratory Medicine; Garner O, Dongarwar D et. al.

May 28th, 2021 - Hypoxemic respiratory failure is a common manifestation of COVID-19 pneumonia. Early in the COVID-19 pandemic, patients with hypoxemic respiratory failure were, at times, being intubated earlier than normal; in part because the options of heated humidified high flow nasal cannula (HFNC) and non-invasive ventilation (NIV) were considered potentially inadequate and to increase risk of virus aeros...

Histopathological findings and clinicopathologic correlation in COVID-19: a systematic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141548
Modern Pathology : an Official Journal of the United Stat... Caramaschi S, Kapp ME et. al.

May 26th, 2021 - The severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) pandemic has had devastating effects on global health and worldwide economy. Despite an initial reluctance to perform autopsies due to concerns for aerosolization of viral particles, a large number of autopsy studies published since May 2020 have shed light on the pathophysiology of Coronavirus disease 2019 (COVID-19). This review...

Airway Surgery for Laryngotracheal Stenosis During the COVID-19 Pandemic: Institutional...
https://doi.org/10.1053/j.jvca.2021.04.002
Journal of Cardiothoracic and Vascular Anesthesia; Elsayed HH, Moharram AA

May 18th, 2021 - The management of laryngotracheal stenosis is challenging, as patients usually require in-time interventions. The current coronavirus disease 2019 (COVID-19) pandemic has added unique challenges to this procedure. The presence of the virus in high concentrations in the aerodigestive tract and the need for an open airway during surgery can increase the risk of aerosolization of the virus and sub...

Learning to Interpret Pediatric Vocal Fold Mobility: A Laryngeal Ultrasound Training Mo...
https://doi.org/10.1002/lary.29582
The Laryngoscope; Alexander NL, Tran B et. al.

Apr 24th, 2021 - Vocal fold movement impairment (VFMI) in infants and children is most commonly evaluated by flexible nasolaryngoscopy (FNL). FNL in this population can be challenging due to movement, floppy supraglottic structures, or secretions. Laryngeal ultrasound (LUS) may be an alternative, less invasive means of evaluating VFMI that also decreases aerosolization during the COVID-19 pandemic. The primary ...

Suction mask device: a simple, inexpensive, and effective method of reducing spread of ...
https://doi.org/10.3171/2020.10.JNS203196
Journal of Neurosurgery; Hara T, Zachariah MA et. al.

Apr 24th, 2021 - Aerosol-generating procedures, including endoscopic endonasal surgery (EES), are a major risk for physicians during the COVID-19 pandemic. Techniques for reducing aerosolization and risk of transmission of COVID-19 during these procedures would be valuable to the neurosurgical community. The authors aimed to simulate the generation of small-particle aerosols during EES and craniectomy in order ...

A risk assessment tool for resumption of research activities during the COVID-19 pandem...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040756
BMC Medical Research Methodology; Simkovich SM, Thompson LM et. al.

Apr 14th, 2021 - The spread of severe acute respiratory syndrome coronavirus-2 has suspended many non-COVID-19 related research activities. Where restarting research activities is permitted, investigators need to evaluate the risks and benefits of resuming data collection and adapt procedures to minimize risk. In the context of the multicountry Household Air Pollution Intervention (HAPIN) trial conducted in rur...

Aerosols, airflow, and airspace contamination during laparoscopy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083507
The British Journal of Surgery; Hardy N, Dalli J et. al.

Apr 9th, 2021 - Laparoscopic surgery has been undermined throughout the COVID-19 pandemic by concerns that it may generate an infectious risk to the operating team through aerosolization of peritoneal particles. There is anyway a need for increased awareness and understanding of the occupational hazard for surgical teams regarding unfiltered escape of pollutants generated by surgical smoke and other microbials...

Clear plastic bags effectively limit aerosolization and droplet spray during extubation...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955927
Journal of Clinical Anesthesia; Ajimi J, Kosaka M et. al.

Apr 3rd, 2021 - Clear plastic bags effectively limit aerosolization and droplet spray during extubation in the era of COVID-19.|2021|Ajimi J,Kosaka M,Takahashi M,Furuya H,Nishiyama J,|

Difficult Airway Management in Adult COVID-19 Patients: Statement by the Society of Air...
https://doi.org/10.1213/ANE.0000000000005554
Anesthesia and Analgesia; Foley LJ, Urdaneta F et. al.

Mar 13th, 2021 - The COVID-19 disease, caused by Coronavirus SARS-CoV-2, often results in severe hypoxemia requiring airway management. Because SARS CoV-2 virus is spread via respiratory droplets, bag-mask ventilation, intubation, and extubation may place health care workers (HCW) at risk. While existing recommendations address airway management in patients with COVID-19, no guidance exists specifically for dif...

Closed Bronchoscopy System: An Innovative Approach to Minimize Aerosolization During Br...
https://doi.org/10.1213/XAA.0000000000001417
A&A Practice; Sharkey A, Zucco L et. al.

Mar 10th, 2021 - Health care workers performing aerosolizing procedures on patients with transmissible infections such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are at high-risk for disease acquisition. Current guidelines designed to protect health care workers during aerosolizing procedures prioritize personal protective equipment and enhanced infection control techniques, in particular d...

Phrenic nerve study as outcome in clinical trials for amyotrophic lateral sclerosis.
https://doi.org/10.1080/21678421.2021.1895842
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration; Pinto S, De Carvalho M

Mar 9th, 2021 - Introduction: Respiratory tests are fundamental for monitoring respiratory function in ALS, and essential in clinical trials. Slow vital capacity (SVC) was canceled in some countries to prevent COVID-19 transmission. We aimed to test phrenic nerve motor responses as an option to SVC in clinical trials. Methodology: Patients followed-up in our unit were selected respecting inclusion criteria use...

The Answer to the Silent "Super Spreader": An Innovative Way to Manage Chest Drains on ...
https://doi.org/10.1213/XAA.0000000000001419
A&A Practice; Angeles C, Magharious P et. al.

Mar 9th, 2021 - The risk of aerosol transmission has been a key factor for the rapid dissemination of the coronavirus pandemic. Transportation of coronavirus disease 2019 (COVID-19)-infected patients with active air leaks could expose unprotected health care personnel and other patients to aerosolized viral particles. We devised a way to avoid aerosolization while the chest tube drain is on water seal. It invo...

Recommended Approaches to Minimize Aerosol Dispersion of SARS-CoV-2 During Noninvasive ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921720
Chest Patout M, Fresnel E et. al.

Mar 6th, 2021 - SARS-CoV-2 aerosolization during noninvasive positive-pressure ventilation may endanger health care professionals. Various circuit setups have been described to reduce virus aerosolization. However, these setups may alter ventilator performance. What are the consequences of the various suggested circuit setups on ventilator efficacy during CPAP and noninvasive ventilation (NIV)? Eight circuit s...

Increasing Recruitment Trends To Psychiatry In Canada.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505736
Academic Psychiatry : the Journal of the American Associa... Morra A, Lee EK et. al.

Mar 5th, 2021 - We reviewed the clinical utility of perfusion (Q)-single-photon emission computed tomography (SPECT)/CT for diagnosing pulmonary embolus (PE) in patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Following the World Health Organization's declaration of a global pandemic, our department policy recommended Q-only SPECT/CT for all patients undergoing nuclear me...