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Objective evaluation of odor loss in COVID-19 and other suspected cases.
https://doi.org/10.1016/j.amjoto.2020.102761
American Journal of Otolaryngology; Seden N, Yiğit E et. al.

Oct 20th, 2020 - COVID-19 is a pandemic disease known with one of the symptoms is sudden onset anosmia. This symptom sometimes may be the only sign of the disease, therefore it must be research widely. We aim to evaluate odor dysfunction in COVID-19 patients objectively and safely without any risk of transmitting the disease. The odor threshold test was performed on 105 patients hospitalized at the XXXX Trainin...

Nitric oxide's physiologic effects and potential as a therapeutic agent against Covid-19.
https://doi.org/10.1088/1752-7163/abc302
Journal of Breath Research; Ricciardolo FLM, Bertolini F et. al.

Oct 20th, 2020 - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for COVID-19 pneumonia, a pandemic that precipitates huge pressures on the world's social and economic systems. Disease severity varies among individuals. SARS-CoV-2 infection can be associated with e.g. flu-like symptoms, dyspnoea, severe interstitial pneumonia, acute respiratory distress syndrome, multiorgan dysfu...

A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndro...
https://doi.org/10.1016/j.jadohealth.2020.09.001
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine; Tilley K, Ayvazyan V et. al.

Oct 19th, 2020 - The aim of the study was to determine the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in a university student population. This was a cross-sectional survey study based on the World Health Organization population-based seroepidemiological investigational protocol for SARS-CoV-2 conducted between April 29, 2020, and May 8, 2020, examining SARS-CoV-2 antib...

A Prospective Sero-epidemiological Evaluation of SARS-CoV-2 among Health Care Workers i...
https://doi.org/10.1016/j.ijid.2020.10.026
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases; Herzberg J, Vollmer T et. al.

Oct 19th, 2020 - New York City (NYC) has endured the greatest burden of COVID-19 infections in the US. Health inequities in South Bronx predisposed this community to a greater number of infections cases, hospitalisations and mortality. Health Care Workers (HCWs) are at high-risk of exposure to the infection. This study aims to assess seroprevalence and associated characteristics of consenting HCWs from a NYC pu...

Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377802
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia; Thu SS, Matin N et. al.

Oct 19th, 2020 - Since the outbreak with novel corona virus in December 2019, a myriad of different neurological manifestations in patients with COVID-19 infection have been reported. We present a case of non-traumatic intracranial hemorrhage in the olfactory gyrus in a patient who tested positive for SARS-COV-2. The area of hemorrhage is not a common location for spontaneous hemorrhage. Given that loss of smel...

A meta-analysis of 67 studies with presenting symptoms & laboratory tests of COVID-19 p...
https://doi.org/10.1002/lary.29207
The Laryngoscope; Mair M, Singhavi H et. al.

Oct 17th, 2020 - The objective of this meta-analysis was to look at the pooled prevalence of symptoms, Laboratory tests and imaging of all COVID-19 infected patients. This will allow better identification of potential COVID-19 patients and take appropriate precautions. We searched three databases, PubMed, EMBASE and Ovid to identify studies published between Dec-2019 and May-2020. All studies reporting upper-ae...

Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557299
The Journal of Infection; Wells PM, Doores KJ et. al.

Oct 17th, 2020 - Understanding of the true asymptomatic rate of infection of SARS-CoV-2 is currently limited, as is understanding of the population-based seroprevalence after the first wave of COVID-19 within the UK. The majority of data thus far come from hospitalised patients, with little focus on general population cases, or their symptoms. We undertook enzyme linked immunosorbent assay characterisation of I...

Post lockdown COVID-19 seroprevalence and circulation at the time of delivery, France.
https://doi.org/10.1371/journal.pone.0240782
PloS One; Mattern J, Vauloup-Fellous C et. al.

Oct 15th, 2020 - To fight the COVID-19 pandemic, lockdown has been decreed in many countries worldwide. The impact of pregnancy as a severity risk factor is still debated, but strict lockdown measures have been recommended for pregnant women. To evaluate the impact of the COVID-19 pandemic and lockdown on the seroprevalence and circulation of SARS-CoV-2 in a maternity ward in an area that has been significantly...

Headache characteristics in COVID-19 pandemic-a survey study.
https://doi.org/10.1186/s10194-020-01188-1
The Journal of Headache and Pain; Uygun Ö, Ertaş M et. al.

Oct 14th, 2020 - Headache is the most common COVID-19-related neurological symptom. We aimed to reveal diagnostic clues of headache for COVID-19 infection and to investigate the course of primary headaches during the pandemic. We developed a detailed web-based questionnaire screening the characteristics and course of headaches besides clinical COVID-19 features. The participants were grouped according to being ...

Olfactory Cleft Measurements and COVID-19-Related Anosmia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554408
Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery; Altundag A, Yıldırım D et. al.

Oct 13th, 2020 - This study aimed to investigate the differences in olfactory cleft (OC) morphology in coronavirus disease 2019 (COVID-19) anosmia compared to control subjects and postviral anosmia related to infection other than severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Prospective. This study comprises 91 cases, including 24 cases with anosmia due to SARS-CoV-2, 38 patients with olfactory ...

COVID-19 and first trimester spontaneous abortion: a case-control study of 225 pregnant...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543983
American Journal of Obstetrics and Gynecology; Cosma S, Carosso AR et. al.

Oct 11th, 2020 - The disease caused by the "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2) was named Coronavirus Disease 19 (COVID-19) and classified as a global public health emergency. The evidence related to the impact of COVID-19 on pregnancy are limited to the second and the third trimester of pregnancy, while data on the first trimester are scant. Many viral infections can be harmful to the...

SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544689
Nature Communications; Rudberg AS, Havervall S et. al.

Oct 9th, 2020 - SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies against SARS-CoV-2 was 19.1% among the 2149 healthcare workers recruited between April 14th and Ma...

Anosmia is associated with lower in-hospital mortality in COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527278
Journal of the Neurological Sciences; Talavera B, García-Azorín D et. al.

Oct 9th, 2020 - Anosmia is common in Coronavirus disease 2019, but its impact on prognosis is unknown. We analysed whether anosmia predicts in-hospital mortality; and if patients with anosmia have a different clinical presentation, inflammatory response, or disease severity. Retrospective cohort study including all consecutive hospitalized patients with confirmed Covid-19 from March 8th to April 11th, 2020. We...

Follow-up of adults with non-critical COVID-19 two months after symptoms' onset.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534895
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases; Carvalho-Schneider C, Laurent E et. al.

Oct 8th, 2020 - To describe the clinical evolution and predictors of symptom persistence during 2-month follow-up in adults with non-critical COVID-19. Descriptive clinical follow-up (days 7, 30 [D30] and 60 [D60]) of 150 patients with non-critical COVID-19 confirmed by RT-PCR at Tours University Hospital from March 17 to June 3, 2020, including demographic, clinical and laboratory data collected from the elec...

Olfactory and Gustatory Dysfunctions as a Clinical Manifestation of Coronavirus Disease...
https://doi.org/10.1177/0003489420963165
The Annals of Otology, Rhinology, and Laryngology; Ramasamy K, Saniasiaya J et. al.

Oct 7th, 2020 - To investigate the prevalence of olfactory and gustatory dysfunction among patients with COVID-19 infection and the recovery rate. Adult patients (≥18 years) tested positive for COVID-19 via reverse transcription-polymerase chain reaction (RT-PCR) and admitted in Hospital Tuanku Ja'afar Seremban, Malaysia, were recruited in this study. Patients completed a questionnaire via telephone interview ...

COVID-19 in children: current evidence and key questions.
https://doi.org/10.1097/QCO.0000000000000690
Current Opinion in Infectious Diseases; Munro APS, Faust SN

Oct 7th, 2020 - SARS-CoV-2 infection in children has been less well characterized than in adults, primarily due to a significantly milder clinical phenotype meaning many cases have gone undocumented by health professionals or researchers. This review outlines the current evidence of the epidemiology of infection in children, the clinical manifestations of disease, the role of children in transmission of the vi...

Impact of the COVID-19 pandemic on patients with systemic lupus erythematosus: Observat...
https://doi.org/10.1177/0961203320962855
Lupus Rathi M, Singh P et. al.

Oct 6th, 2020 - The ongoing pandemic of COVID-19 has led to severe disruption of healthcare services worldwide. We conducted this study to assess the impact of COVID-19 pandemic on the management of Systemic Lupus Erythematosus (SLE) patients who were enrolled in the nation-wide inception cohort. A questionnaire was administered to the SLE patients enrolled in the inception cohort. Questions related to the eff...

Clinical Characteristics of COVID-19 Patients With Gastrointestinal Symptoms in Norther...
https://doi.org/10.14309/ajg.0000000000000965
The American Journal of Gastroenterology; Schettino M, Pellegrini L et. al.

Oct 3rd, 2020 - The most typical presentation of COVID-19 is an acute respiratory syndrome whose most common symptoms include fever, cough, and dyspnea. However, gastrointestinal symptoms, such as diarrhea and nausea/vomiting, are increasingly reported in patients affected by COVID-19. This study aimed to describe the prevalence and time of onset of gastrointestinal symptoms in patients affected by COVID-19 an...

Neurological consequences of COVID-19: what have we learned and where do we go from here?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525232
Journal of Neuroinflammation; Jarrahi A, Ahluwalia M et. al.

Oct 1st, 2020 - The coronavirus disease-19 (COVID-19) pandemic is an unprecedented worldwide health crisis. COVID-19 is caused by SARS-CoV-2, a highly infectious pathogen that is genetically similar to SARS-CoV. Similar to other recent coronavirus outbreaks, including SARS and MERS, SARS-CoV-2 infected patients typically present with fever, dry cough, fatigue, and lower respiratory system dysfunction, includin...

Repurposing existing drugs for COVID-19: an endocrinology perspective.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523486
BMC Endocrine Disorders; Cadegiani FA

Sep 30th, 2020 - Coronavirus Disease 2019 (COVID-19) is a multi-systemic infection caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), that has become a pandemic. Although its prevailing symptoms include anosmia, ageusia, dry couch, fever, shortness of brief, arthralgia, myalgia, and fatigue, regional and methodological assessments vary, leading to heterogeneous clinical descriptio...