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Sense and sensitivity: can an inaccurate test be better than no test at all?
https://doi.org/10.1136/medethics-2021-107234
Journal of Medical Ethics; Pugh J, Wilkinson D et. al.

Apr 6th, 2021 - The UK government has put lateral flow antigen tests (LFATs) at the forefront of its strategy to scale-up testing in the coronavirus pandemic. However, evidence from a pilot trial using an LFAT to identify asymptomatic infections in the community suggested that the test missed over half of the positive cases in the tested population. This raises the question of whether it can be ethical to use ...

First Detection of Severe Acute Respiratory Syndrome Coronavirus 2 on the Surfaces of T...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004146
International Journal of Environmental Research and Publi... Montagna MT, De Giglio O et. al.

Apr 3rd, 2021 - A Coronavirus disease (COVID-19), caused by a new virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spreads via direct contact through droplets produced by infected individuals. The transmission of this virus can also occur via indirect contact if objects and surfaces are contaminated by secretions from individuals with COVID-19 or asymptomatic carriers. Environmental c...

What was the Prevalence of COVID-19 in Asymptomatic Patients Undergoing Orthopaedic Sur...
https://doi.org/10.1097/CORR.0000000000001697
Clinical Orthopaedics and Related Research; Gutman MJ, Patel MS et. al.

Mar 15th, 2021 - Many patients with coronavirus disease 2019 (COVID-19) are asymptomatic. The prevalence of COVID-19 in orthopaedic populations will vary depending on the time and place where the sampling is performed. The idea that asymptomatic carriers play a role is generalizable but has not been studied in large populations of patients undergoing elective orthopaedic surgery. We therefore evaluated this top...

Systematic screening on admission for SARS-CoV-2 to detect asymptomatic infections.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912536
Antimicrobial Resistance and Infection Control; Stadler RN, Maurer L et. al.

Feb 28th, 2021 - The proportion of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains elusive and the potential benefit of systematic screening during the SARS-CoV-2-pandemic is controversial. We investigated the proportion of asymptomatic inpatients who were identified by systematic screening for SARS-CoV-2 upon hospital admission. Our analysis revealed that systemati...

Ultra-rapid detection of SARS-CoV-2 in public workspace environments.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904170
PloS One; Yaren O, McCarter J et. al.

Feb 24th, 2021 - Managing the pandemic caused by SARS-CoV-2 requires new capabilities in testing, including the possibility of identifying, in minutes, infected individuals as they enter spaces where they must congregate in a functioning society, including workspaces, schools, points of entry, and commercial business establishments. Here, the only useful tests (a) require no sample transport, (b) require minima...

SARS-CoV-2 viral shedding characteristics and potential evidence for the priority for f...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899334
PloS One; Yuan C, Wang H et. al.

Feb 22nd, 2021 - This study aimed to identify the specimen type that has high positivity and its proper sampling time for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing to promote diagnostic efficiency. All SARS-CoV-2-infected patients with a laboratory-confirmed diagnosis in Zhoushan City were followed up for viral shedding in respiratory tract specimens and faecal samples. Positivity was...

With COVID Vaccinations Comes a Potential Nightmare Scenario
https://www.medscape.com/viewarticle/945433

Feb 9th, 2021 - This transcript has been edited for clarity. Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. No one talked about it much, but public health professionals were all aware of a potential nightmare scenario when COVID vaccinations started up in bulk. No, not a slew of severe adverse events; the clinical trials m...

Feasibility and Predictive Performance of a Triage System for Patients with Cancer Duri...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014855
The Oncologist; Fasola G, Pelizzari G et. al.

Feb 4th, 2021 - Triage procedures have been implemented to limit hospital access and minimize infection risk among patients with cancer during the coronavirus disease (COVID-19) outbreak. In the absence of prospective evidence, we aimed to evaluate the predictive performance of a triage system in the oncological setting. This retrospective cohort study analyzes hospital admissions to the oncology and hematolog...

At the Urging of Nursing Homes, a Law Is Amended and COVID Court Claims Are Slowed
https://www.medscape.com/viewarticle/944954

Jan 31st, 2021 - (Reuters) - Garnice Robertson wants accountability for her mother's death from COVID-19 caught while she was living at a Kansas nursing home that allegedly failed to prevent an outbreak of the disease. An unexpected legal hurdle stands in her way. The nursing home argues it has complete legal immunity for lawsuits like Robertson's stemming from COVID-19. It cites recent changes to a 2005 law by...

SARS-CoV-2 infection in asymptomatic healthcare workers at a clinic in Chile.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842995
PloS One; Olmos C, Campaña G et. al.

Jan 28th, 2021 - Asymptomatic SARS-CoV-2 infection of healthcare workers (HCWs) has been reported as a key player in the nosocomial spreading of COVID-19. Early detection of infected HCWs can prevent spreading of the virus in hospitals among HCWs and patients. We conducted a cross-sectional study to determine the asymptomatic infection of HCWs in a private clinic in the city of Santiago, Chile. Our study was co...

Clinical course and challenging management of early COVID-19 infection after heart tran...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816134
BMC Infectious Diseases; Tchana-Sato V, Ancion A et. al.

Jan 21st, 2021 - There are limited data on Coronavirus disease 2019 (COVID-19) in solid organ transplant patients, especially in heart transplant recipients, with only a few case reports and case series described so far. Heart transplant recipients may be at particular high risk due to their comorbidities and immunosuppressed state. This report describes the clinical course and the challenging management of ear...

Madrid Begins Mass Testing Young People for COVID-19
https://www.medscape.com/viewarticle/944424

Jan 20th, 2021 - MADRID (Reuters) - Health authorities in Madrid began mass testing hundreds of young people for COVID-19 at universities on Wednesday to detect asymptomatic carriers in one of the groups with the highest rates of transmission. With the country in the grip of a third wave of infection, authorities called on young people to attend makeshift medical centres at nine university campuses to take a ra...

Detection-based prioritisation: Framework of multi-laboratory characteristics for asymp...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647899
Artificial Intelligence in Medicine; Albahri AS, Hamid RA et. al.

Jan 19th, 2021 - Corona virus (COVID) has rapidly gained a foothold and caused a global pandemic. Particularists try their best to tackle this global crisis. New challenges outlined from various medical perspectives may require a novel design solution. Asymptomatic COVID-19 carriers show different health conditions and no symptoms; hence, a differentiation process is required to avert the risk of chronic virus ...

Parasites and Parasitology in this SARS-CoV-2, COVID-19 World: An American Society of P...
https://doi.org/10.1645/20-158
The Journal of Parasitology; Hillyer JF

Jan 15th, 2021 - The novel coronavirus disease 2019 (COVID-19) is one of the worst global health crises of this generation. The core of this pandemic is the rapid transmissibility of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, its high morbidity and mortality, and the presence of infectious asymptomatic carriers. As a result, COVID-19 has dominated this year's headlines and commanded...

Challenge of post-COVID era: management of cardiovascular complications in asymptomatic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797272
Heart Failure Reviews; Gupta S, Mitra A

Jan 11th, 2021 - Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a highly pathogenic member of family coronaviridae, has caused an exponentially growing global pandemic termed as the coronavirus disease 2019 (COVID-19) with more than 12 million cases worldwide till date. This deadly disease has average fatality rate of 6.5% and even higher among elderly patients and patients with comorbidities. SA...

Seroprevalence and asymptomatic carrier status of SARS-CoV-2 in Wuhan City and other pl...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790301
PLoS Neglected Tropical Diseases; Duan S, Zhou M et. al.

Jan 7th, 2021 - Wuhan City (WH) in China was the first place to report COVID-19 in the world and the outbreak of COVID-19 was controlled in March of 2020 in WH. It is unclear what percentage of people were infected with SARS-CoV-2 and what percentage of population is carriers of SARS-CoV-2 in WH. We retrospectively analyzed the SARS-CoV-2 IgG and IgM antibody positive rates in 63,107 healthy individuals from W...

The role of serum specific- SARS-CoV-2 antibody in COVID-19 patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759121
International Immunopharmacology; Chen H, Zhang X et. al.

Jan 5th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for coronavirus disease 2019 (COVID-19), has rapidly spread, resulting in considerable casualties and serious economic loss worldwide. Disease severity and related symptoms markedly vary among individuals. A large number of patients present atypical symptoms, which represent a big challenge for early diagnosis and prompt ...

Informed sequential pooling approach to detect SARS-CoV-2 infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773195
PloS One; Millioni R, Mortarino C

Dec 30th, 2020 - The alarming spread of the pandemic coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus requires several measures to reduce the risk of contagion. Every successful strategy in controlling the SARS-CoV-2 infection depends on timely diagnosis, which should include testing of asymptomatic carriers. Consequently, increasing the throughput for clinical laboratories for the purposes of...

Interrelations between COVID-19 and other disorders.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833539
Clinical Immunology (Orlando, Fla.); Gasmi A, Peana M et. al.

Dec 17th, 2020 - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory tract virus that causes Coronavirus disease (COVID-19). The virus originated in Wuhan, China, in December 2019 and has spread across the globe to-date. The disease ranges from asymptomatic carriers to symptoms such as fever, sore throat, cough, lung infections, and in severe cases, acute respiratory distress syndr...

Asymptomatic patients as a source of transmission of COVID-19 in homeless shelters.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834802
International Journal of Infectious Diseases : IJID : Off... Ralli M, Morrone A et. al.

Dec 15th, 2020 - Asymptomatic carriers account for over a third of all Coronavirus Disease 19 (COVID-19) cases and are characterized by the absence of symptoms but the same infectivity as symptomatic infections. The high percentage of asymptomatic COVID-19 patients is significant in settings with specific vulnerabilities, such as homeless shelters, where the consequences of an outbreak may be dramatic. In this ...