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Molecular epidemiology of SARS-CoV-2 clusters caused by asymptomatic cases in Anhui Pro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719853
BMC Infectious Diseases; Yuan Y, He J et. al.

Dec 8th, 2020 - COVID-19 is a newly emerging disease caused by a novel coronavirus (SARS-CoV-2), which spread globally in early 2020. Asymptomatic carriers of the virus contribute to the propagation of this disease, and the existence of asymptomatic infection has caused widespread fear and concern in the control of this pandemic. In this study, we investigated the origin and transmission route of SARS-CoV-2 in...

Angiotensin-converting enzyme 2 and COVID-19: patients, comorbidities, and therapies.
https://doi.org/10.1152/ajplung.00259.2020
American Journal of Physiology. Lung Cellular and Molecul... Pathangey G, Fadadu PP et. al.

Nov 25th, 2020 - On March 11, 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19) a pandemic, and the reality of the situation has finally caught up to the widespread reach of the disease. The presentation of the disease is highly variable, ranging from asymptomatic carriers to critical COVID-19. The availability of angiotensin-converting enzyme 2 (ACE2) receptors may reportedly inc...

An overview on COVID-19 pandemic: from discovery to treatment.
https://doi.org/10.2174/1871526520666201109115820
Infectious Disorders Drug Targets; Panati K, Tatireddygari VRA et. al.

Nov 10th, 2020 - Recently, novel coronavirus infection (COVID-19) emerged in Wuhan, China has been declared as pandemic by WHO. Until now, no evidence is documented regarding its wild animal reservoir or intermediary host, but, human-to-human transmission, asymptomatic carriers were very much observed. The number of confirmed cases and death toll have been increased almost all over the world indicating its pote...

Type A Aortic Dissection During COVID-19 Pandemic: Report From Tertiary Aortic Centers ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648657
Seminars in Thoracic and Cardiovascular Surgery; Fukuhara S, Tang H et. al.

Nov 10th, 2020 - Coronavirus disease 2019 (COVID-19) has substantially disrupted many processes of care related to emergency cardiac conditions, while there has been no clinical guidance regarding the management of type A aortic dissection. A retrospective multicenter study involving 52 consecutive patients (mean age 52.3, 28.9% women) with type A aortic dissection during COVID-19 pandemic was conducted at tert...

SARS-CoV-2 seroprevalence and transmission risk factors among high-risk close contacts:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831879
The Lancet. Infectious Diseases; Ng OT, Marimuthu K et. al.

Nov 5th, 2020 - The proportion of asymptomatic carriers and transmission risk factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among household and non-household contacts remains unclear. In Singapore, extensive contact tracing by the Ministry of Health for every diagnosed COVID-19 case, and legally enforced quarantine and intensive health surveillance of close contacts provided a rare op...

Identification of a metabolic, transcriptomic and molecular signature of PNPLA3-mediate...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641518
Hepatology (Baltimore, Md.); Banini BA, P Kumar D et. al.

Nov 1st, 2020 - The global coronavirus disease 2019 (COVID-19) pandemic has posed great challenges in people's daily lives. Highly sensitive laboratory techniques played a critical role in clinical COVID-19 diagnosis and management. In this study the feasibility of using a new digital PCR-based detection assay for clinical COVID-19 diagnosis was investigated by comparing its performance with that of RT-PCR. Cl...

About 17% of COVID-19 Survivors Retest Positive in Follow-Up Study
https://www.medscape.com/viewarticle/940114

Oct 29th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. For reasons unknown, about 1-in-6 people who recovered from COVID-19 subsequently retested positive at least 2 weeks later, researchers reported in a study in Italy. People returned for follow-up visits a mean 17 days after the second negative swab test. Asymptomatic COVID-19 Carriers? "These findings indicate...

Clinical features and antibody response of patients from a COVID-19 treatment hospital ...
https://doi.org/10.1002/jmv.26617
Journal of Medical Virology; Chen Y, Ke Y et. al.

Oct 21st, 2020 - Coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic. A total of 1578 patients admitted into a newly built hospital specialized for COVID-19 treatment in Wuhan, China, were enrolled. Clinical features and the levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin (Ig)M and IgG were analyzed. In total, 1532 patients (97.2%) were identified...

Cytosorb filter: An adjunct for survival in the COVID-19 patient in cytokine storm? a c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500900
Heart & Lung : the Journal of Critical Care; Rizvi S, Danic M et. al.

Oct 12th, 2020 - COVID-19 is a pandemic that has affected not only the United States, but the entire world. The impact it has had has overwhelmed the entire healthcare system, from the unknown carrier status, poor testing capabilities to hospitals running out of ventilators for severely ill patients. There has been a variety of potential treatment modalities for the various forms of illness ranging from asympto...

Antibody dynamics to SARS-CoV-2 in asymptomatic COVID-19 infections.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675426
Allergy Lei Q, Li Y et. al.

Oct 11th, 2020 - The missing asymptomatic COVID-19 infections have been overlooked because of the imperfect sensitivity of the nucleic acid testing (NAT). Globally understanding the humoral immunity in asymptomatic carriers will provide scientific knowledge for developing serological tests, improving early identification, and implementing more rational control strategies against the pandemic. Utilizing both NAT...

Epidemiological analysis of 67 local COVID-19 clusters in Sichuan Province, China.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543676
BMC Public Health; Mao S, Huang T et. al.

Oct 9th, 2020 - This study was intended to investigate the epidemiological characteristics of COVID-19 clusters and the severity distribution of clinical symptoms of involved cases in Sichuan Province, so as to provide information support for the development and adjustment of strategies for the prevention and control of local clusters. The epidemiological characteristics of 67 local clusters of COVID-19 cases ...

Care homes and COVID-19 in Hong Kong: how the lessons from SARS were used to good effect.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665295
Age and Ageing; Chow L

Oct 9th, 2020 - In Hong Kong, about 15% of older people (aged 80 and above) live in care homes, one of the highest proportions in the world. During the spread of severe acute respiratory syndrome in 2003, the crude fatality rate for older people in care homes that were infected was 72%. After taking the advice of a team of international experts, the Hong Kong Government implemented comprehensive preventive mea...

Role of a Pediatric Cardiologist in the COVID-19 Pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533115
Pediatric Cardiology; Niaz T, Hope K et. al.

Oct 5th, 2020 - Coronavirus disease 2019 (COVID-19) has affected patients across all age groups, with a wide range of illness severity from asymptomatic carriers to severe multi-organ dysfunction and death. Although early reports have shown that younger age groups experience less severe disease than older adults, our understanding of this phenomenon is in continuous evolution. Recently, a severe multisystem in...

Carbapenemase-producing Enterobacterales outbreak: Another dark side of COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529666
American Journal of Infection Control; Farfour E, Lecuru M et. al.

Oct 4th, 2020 - In the hospital department dedicated to COVID-19-patient, infection prevention and control measures were upgraded. Therefore, the cross-transmission of other micro-organisms was thought unlikely to occur. However, we report an outbreak of NDM-5-producing Escherichia. coli in a 12-beds ICU dedicated to COVID-19 patients. This outbreak involved 6 patients of which 5 were asymptomatic carriers and...

Asymptomatic carriage rates and case fatality of SARS-CoV-2 infection in residents and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543256
Age and Ageing; Kennelly SP, Dyer AH et. al.

Sep 28th, 2020 - SARS-CoV-2 has disproportionately affected nursing homes (NH). In Ireland, the first NH case COVID-19 occurred on 16 March 2020. A national point-prevalence testing programme of all NH residents and staff took place (18 April 2020 to 5 May 2020). to examine characteristics of NHs across three Irish Community Health Organisations, proportions with COVID-19 outbreaks, staff and resident infection...

COVID-19: Current understanding of its pathophysiology, clinical presentation and treat...
https://doi.org/10.1136/postgradmedj-2020-138577
Postgraduate Medical Journal; Parasher A

Sep 26th, 2020 - The severe acute respiratory syndrome (SARS) coronavirus-2 is a novel coronavirus belonging to the family Coronaviridae and is now known to be responsible for the outbreak of a series of recent acute atypical respiratory infections originating in Wuhan, China. The disease caused by this virus, termed coronavirus disease 19 or simply COVID-19, has rapidly spread throughout the world at an alarmi...

Mass screening of asymptomatic persons for SARS-CoV-2 using saliva.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543374
Clinical Infectious Diseases : an Official Publication Of... Yokota I, Shane PY et. al.

Sep 25th, 2020 - COVID-19 has rapidly evolved to become a global pandemic due largely to the transmission of its causative virus through asymptomatic carriers. Detection of SARS-CoV-2 in asymptomatic people is an urgent priority for the prevention and containment of disease outbreaks in communities. However, few data are available in asymptomatic persons regarding the accuracy of PCR testing. Additionally, alth...

Identification, presence, and possible multifunctional regulatory role of invertebrate ...
https://doi.org/10.1016/j.ygcen.2020.113621
General and Comparative Endocrinology; Fodor I, Zrinyi Z et. al.

Sep 23rd, 2020 - A novel coronavirus (COVID-19) reached pandemic levels by March 11th, 2020, with a destructive impact across socioeconomic domains and all facets of global health, but little is known of its impact on sexual health. To review current knowledge on sexual health-related containment measures during pandemics, specifically COVID-19, and focus on 2 main areas: intimacy and relational dynamics and cl...

Determination of risk factors for predicting the onset of symptoms in asymptomatic COVI...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484673
International Journal of Medical Sciences; Tao PY, Leng L et. al.

Sep 14th, 2020 - Background: The number of asymptomatic infected patients with coronavirus disease 2019 (COVID-2019) is rampaging around the world but limited information aimed on risk factors of asymptomatic infections. The purpose of this study is to investigate the risk factors of symptoms onset and clinical features in asymptomatic COVID-19 infected patients. Methods: A retrospective study was performed in ...

Lessons for Patients With MS and COVID-19
https://www.medscape.com/viewarticle/937300

Sep 11th, 2020 - Two important lessons about managing patients with multiple sclerosis (MS) and COVID-19 have emerged from a hospital clinic in Madrid that managed COVID-infected patients with MS through the peak of the pandemic: Combined polymeric chain reaction and serology testing helped avoid disease reactivation in asymptomatic carriers during the pandemic peak, although after the peak PCR alone proved jus...